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Encyclopedia > Whipple's disease
Whipple's disease
ICD-10 code: K90.8
ICD-9 code: 040.2

Whipple's disease is a rare disease caused by the bacteria Thropheryma whipplei. It is characterised by arthritis, malabsorption, and a number of other symptoms, most notably intestinal lipodystrophy (accumulation of fatty deposits in lymph nodes of the intestine). The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... A rare disease has such a low prevalence in a population that a doctor in a busy general practice would not expect to see more than one case a year. ... Phyla/Divisions Actinobacteria Aquificae Bacteroidetes/Chlorobi Chlamydiae/Verrucomicrobia Chloroflexi Chrysiogenetes Cyanobacteria Deferribacteres Deinococcus-Thermus Dictyoglomi Fibrobacteres/Acidobacteria Firmicutes Fusobacteria Gemmatimonadetes Nitrospirae Omnibacteria Planctomycetes Proteobacteria Spirochaetes Thermodesulfobacteria Thermomicrobia Thermotogae Bacteria (singular, bacterium) are a major group of living organisms. ... Arthritis (from Greek arthro-, joint + -itis, inflammation) is a group of conditions that affect the health of the bone joints in the body. ... Malabsorption is the state of impaired absorption of nutrients in the small intestine. ...

It was first described by George Hoyt Whipple in 1907: Whipple GH. A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acid in the intestinal and mesenteric lymphatic tissues. Bull Johns Hopkins Hosp 1907;18:382-93. George Hoyt Whipple (August 28, 1878 - February 1, 1976) was one of three recipients in 1934 of the Nobel Prize in physiology or medicine for their work on liver therapy in cases of anemia. ... 1907 was a common year starting on Tuesday (see link for calendar). ...

Health science - Medicine - Gastroenterology
Diseases of the esophagus - stomach
Halitosis - Nausea - Vomiting - GERD - Achalasia - Esophageal cancer - Esophageal varices - Peptic ulcer - Abdominal pain - Stomach cancer - Functional dyspepsia
Diseases of the liver - pancreas - gallbladder - biliary tree
Hepatitis - Cirrhosis - NASH - PBC - PSC - Budd-Chiari syndrome - Hepatocellular carcinoma - Pancreatitis - Pancreatic cancer - Gallstones - Cholecystitis
Diseases of the small intestine
Peptic ulcer - Intussusception - Malabsorption (e.g. celiac disease, lactose intolerance, fructose malabsorption, Whipple's disease) - Lymphoma
Diseases of the colon
Diarrhea - Appendicitis - Diverticulitis - Diverticulosis - IBD (Crohn's disease and Ulcerative colitis) - Irritable bowel syndrome - Constipation - Colorectal cancer - Hirschsprung's disease - Pseudomembranous colitis

  Results from FactBites:
Whipple's Disease Information on Healthline (838 words)
Whipple's disease is a rare infectious disorder that can affect many areas of the body, including the gastrointestinal and central nervous systems.
Whipple's disease, also known as intestinal lipodystrophy, was first reported in 1907 by George Hoyt Whipple (1878–1976).
Whipple's disease has traditionally been regarded as a malabsorption disease of the small intestine, but in most cases the first symptoms are arthritic joints, which can precede the malabsorption symptoms of Whipple's disease by many years.
CIGNA - Whipple Disease (2142 words)
Other symptoms of Whipple disease may include: abnormally enlarged lymph nodes that are firm but usually not tender, an abnormally enlarged spleen (splenomegaly), increased color (pigmentation) of the skin, a decrease in blood pressure (hypotension), and abnormally high fevers that come and go.
Ulcerative colitis is an acute inflammatory bowel disease characterized by diarrhea and blood in the stools because of multiple, irregular ulcerations of the bowel.
Immunosuppressive therapy in Whipple’s disease patients is the association with the appearance of gastrointestinal manifestations.
  More results at FactBites »



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