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Encyclopedia > Venezuelan hemorrhagic fever
Guanarito virus
Virus classification
Group: Group V ((-)ssRNA)
Family: Arenaviridae
Genus: Arenavirus

Guanarito virus
Viruses can be classified in several ways, such as by their geometry, by whether they have envelopes, by the identity of the host organism they can infect, by mode of transmission, or by the type of disease they cause. ... An RNA virus is a virus that either uses RNA as its genetic material, or whose genetic material passes through an RNA intermediate during replication. ... Arenavirus is a genus of virus. ... Arenavirus is a genus of virus. ...

Venezualan hemorrhagic fever (VHF) is a zoonotic human illness, first identified in 1989, causing fever and malaise followed by hemorrhagic manifestations and convulsions. It is fatal in 30% of cases. The disease is endemic to Portuguesa state and Barinas state in Venezuala . The causal agent, Guanarito virus, is spread to humans through contact with the excreta of two rodent species: the short-tailed cane mouse (Zygodontomys brevicauda), and the cotton rat (Sigmodon alstoni). Human-to-human transmission of the virus has not been observed. Zoonosis is any infectious disease that can be transmitted from animals, both wild and domestic, to humans. ... Portuguesa may refer to: Portuguese, relating to Portugal Portuguesa State, a state of Venezuela. ... Barinas is a city in west central Venezuela. ... The Bolivarian Republic of Venezuela (Spanish: República Bolivariana de Venezuela)1 is a country in northern South America. ...

Guanarito virus is a member of the Arenavirus genus of negative single-stranded RNA viruses, and is closely related to a number of other rodent-borne emerging viruses that cause hemorrhagic fever in South America. Arenavirus is a genus of virus. ... Ribonucleic acid (RNA) is a nucleic acid consisting of a string of covalently-bound nucleotides. ... Three types of viruses: a bacterial virus, otherwise called a bacteriophage (left center); an animal virus (top right); and a retrovirus (bottom right). ... Viral hemorrhagic fevers are a group of illnesses that are caused by several distinct families of viruses: Arenavirus, Filoviridae, Bunyaviridae and Flavivirus. ...

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Hemorrhaging, neurologic signs and symptoms, and leukopenia and thrombocytopenia are much more common in the three Latin American hemorrhagic fevers than in Lassa fever.
Differential clinical diagnosis of the arenavirus hemorrhagic fevers is complex.
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