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Encyclopedia > Ultrafiltration (renal)

In biological terms, Ultrafiltration occurs at the barrier between the blood and the filtrate in the renal corpuscle or Bowman's capsule in the kidneys. The Bowman's capsule contains a dense capillary network called the glomerulus. Blood flows into these capillaries through a wide afferent arteriole and leaves through a narrower efferent arteriole. The blood pressure inside these capillaries is high because: A renal corpuscle is the initial filtering component of a nephron in the kidney. ... Bowmans Capsule is a blind sac at the beginning of a the tubular component of a nephron in the mammalian kidney. ... Human kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ... The glomerulus is a capillary bed found surrounded by the Bowmans capsule of the nephron in the vertebrate kidney. ... The word capillary is used to describe any very narrow tube or channel through which a fluid can pass. ... An arteriole is a blood vessel that extends and branches out from an artery and leads to capillaries. ...

  1. The renal artery contains blood at very high pressure which enters the glomerulus via the short afferent arteriole.
  2. The efferent arteriole has a smaller diameter than the afferent arteriole.

The high pressure forces small molecules such as water, glucose, amino acids, sodium chloride and urea through the filter, from the blood in the glomerular capsule across the basement membrane of the Bowman's capsule and into the nephron. This type of high pressure filtration is ultrafiltration. The fluid formed in this way is called glomerular filtrate. Large molecules such as plasma proteins and blood cells do not pass through the filter because they are too big. Human kidneys viewed from behind with spine removed The renal arteries normally arise off the abdominal aorta and supply the kidneys with blood. ... Water is a tasteless, odourless substance that is essential to all known forms of life and is known as the universal solvent. ... Glucose (Glc), a monosaccharide (or simple sugar), is the most important carbohydrate in biology. ... In chemistry, an amino acid is any molecule that contains both amino and carboxylic acid functional groups. ... Sodium chloride, also known as common salt, table salt, or halite, is a chemical compound with the formula NaCl. ... Urea is an organic compound of carbon, nitrogen, oxygen and hydrogen, with the formula CON2H4 or (NH2)2CO. Urea is also known as carbamide, especially in the recommended International Non-proprietary Names (rINN) in use in Europe. ...


Glomerular pressure is about 75 millimeters of mercury (10 kPa). It is opposed by osmotic pressure(30 mmHg, 4.0 kPa) and hydrostatic pressure (20 mmHg, 2.7 kPa) of solutes present in capsular space. This difference in pressure is called effective pressure(25 mmHg)(3.3 kPa). The torr (symbol: Torr) or millimetre of mercury (mmHg) is a non-SI unit of pressure. ... The pascal (symbol Pa) is the SI unit of pressure. ...


It is also used in hemodialysis to clean whole blood while keeping its composition intact. A hemodialysis machine In medicine, hemodialysis, also haemodialysis, is a method for removing waste products such as potassium and urea, as well as free water from the blood when the kidneys are incapable of this (i. ... Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ...

Urinary system - Kidney - edit
Renal capsule | Renal cortex  (Renal column) | Renal medulla (Renal sinusRenal pyramids) | Renal lobe | Cortical lobule | Medullary ray | Nephron 
afferent circulation: Renal artery → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Renal corpuscle (GlomerulusBowman's capsule)

kidney tubule: Proximal tubule → Loop of Henle (Descending, Thin ascending, Thick ascending)  → Distal convoluted tubule → Connecting tubule → Collecting ducts → Duct of Bellini → Renal papilla → Minor calyx → Major calyx → Renal pelvis → Ureter The urinary system is the organ system that produces, stores, and carries urine. ... Human kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ... The renal capsule is a tough fibrous layer surrounding the kidney and covered in a thick layer of perinephric adipose tissue. ... The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. ... The renal column is tissue between the renal pyramids that allows for support of the renal cortex. ... The renal medulla is the innermost part of the kidney. ... The renal sinus is a cavity within the kidney which is occupied by the renal pelvis, renal calices, blood vessels, nerves and fat. ... Renal pyramids are cone-shaped tissues of the kidney. ... Nephron of the kidney A nephron is the basic structural and functional unit of the kidney. ... Grays Fig. ... Human kidneys viewed from behind with spine removed The renal arteries normally arise off the abdominal aorta and supply the kidneys with blood. ... The afferent arterioles are a group of blood vessels that supply the nephrons in many excretory systems. ... A renal corpuscle is the initial filtering component of a nephron in the kidney. ... Glomerulus refers to two unrelated structures in the body, both named for their globular form. ... Bowmans Capsule is a blind sac at the beginning of a the tubular component of a nephron in the mammalian kidney. ... In the biology of the kidney, the proximal convoluted tubule is the segment of the renal tubule that drains Bowmans capsule. ... In the kidney, the loop of Henle is the portion of the nephron that leads from the proximal convoluted tubule to the distal convoluted tubule. ... Kidney nephron The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting duct system. ... The collecting duct system of the kidney consists of: The connecting tubule The cortical collecting duct The medullary collecting duct Categories: | ... Position of the duct of Bellini in the kidney The duct of Bellini is an anatomical structure of the kidneys, also known as papillary duct. ... The renal pelvis represents the dilated proximal part of the ureter. ... Transverse section of ureter. ...


efferent circulation: Glomerulus → Efferent arterioles → Peritubular capillaries/Vasa recta → Arcuate veinInterlobar veinsRenal vein Grays Fig. ... The glomerulus is a capillary bed found surrounded by the Bowmans capsule of the nephron in the vertebrate kidney. ... The Efferent arterioles are a group of blood vessels that are part of the urinary system of many animals. ... A nephron, the vasa recta is labelled arteria recta In the blood supply of the kidney, the vasa recta form a series of straight capillaries (recta is from the Latin for straight) that descend from the cortex into the medulla. ... Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ...


juxtaglomerular apparatus: Macula densaJuxtaglomerular cells, Extraglomerular mesangial cells The juxtaglomerular apparatus is a renal structure consisting of the macula densa, mesangial cells, and juxtaglomerular cells. ... In the kidney, the macula densa is an area of closely packed specialized cells lining the distal convoluted tubule where it lies next to the glomerular vascular pole. ... The juxtaglomerular cells are specialized cells that stimulate the secretion of the adrenal hormone aldosterone and play a major role in renal autoregulation, the kidneys self-governance. ...

Renal physiology
Filtration - Ultrafiltration | Countercurrent exchange | Glomerular basement membrane | Podocyte | Filtration slits | Intraglomerular mesangial cells

Hormones affecting filtration - Antidiuretic hormone (ADH) | Aldosterone | Atrial natriuretic peptide Renal physiology is the study of the physiology of the kidneys. ... In chemistry, alchemy and water treatment, filtration is the process of using a filter to mechanically separate a mixture. ... Ultrafiltration (UF) is a variety of membrane filtration in which hydrostatic pressure forces a liquid against a semipermeable membrane. ... Countercurrent exchange is a mechanism used to transfer some component of a fluid from one flowing current of fluid to another across a permeable barrier between them. ... The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration though the filtration slits between the podocytes , separating the blood on the inside from the urine on the outside. ... Podocytes are cells of the visceral epithelium in the kidneys and form a crucial component of the glomerular filtration barrier by covering the exterior basement surface of the glomerular capillary and maintaining a massive filtration surface. ... Antidiuretic hormone (ADH), or arginine vasopressin (AVP), is a peptide hormone produced by the hypothalamus, and stored in the posterior part of the pituitary gland. ... Aldosterone is a steroid hormone synthesized from cholesterol by the enzyme aldosterone synthase. ... Atrial natriuretic factor (ANF), atrial natriuretic peptide (ANP) or atriopeptin, is a polypeptide hormone involved in the homeostatic control of body water and sodium. ...


Endocrine - Renin | Erythropoietin (EPO) | Calcitriol (Active vitamin D) | Prostaglandins The endocrine system is a control system of ductless endocrine glands that secrete chemical messengers called hormones that circulate within the body via the bloodstream to affect distant organs. ... Renin, also known as angiotensinogenase, is a circulating enzyme (EC 3. ... Erythropoietin Erythropoietin (or EPO) is a glycoprotein hormone that is a growth factor for erythrocyte (red blood cell) precursors in the bone marrow. ... Vitamin D is a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. ... Chemical structure of prostaglandin E1 (PGE1). ...

Assessing Renal function / Measures of dialysis
Glomerular filtration rate | Creatinine clearance | Renal clearance ratio | Urea reduction ratio | Kt/V | Standardized Kt/V | Hemodialysis product

 
 

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