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Encyclopedia > Tromantadine
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Tromantadine is an antiviral medicine used to treat herpes simplex virus. Chemically it is N-1-adamantyl-N-[2-(dimethyl amino)ethoxy] acetamide. It is available in a topical gel under trade name Viru-Merz. Its performance is similar to aciclovir. Antiviral drugs are a class of medication used specifically for treating viral infections. ... Medicine on the Web NLM (National Library of Medicine, contains resources for patients and healthcare professionals) Virtual Hospital (digital health sciences library by the University of Iowa) Online Medical Dictionary Collection of links to free medical resources Categories: Medicine | Health ... Jump to: navigation, search The Herpes simplex virus infection (common names: herpes, cold sores) is a common, contagious, incurable, and in some cases sexually transmitted disease caused by a double-stranded DNA virus. ... A gel (from the lat. ... Aciclovir (INN) or acyclovir (USAN), marketed as Zovirax®, is one of the main antiviral drugs. ...

Tromantadine inhibits the early and late events in the virus replication cycle. It changes the glycoproteins of the host cells, therefore impedes the absorption of the virus. It inhibits penetration of the virus. It also prevents uncoating of the virions. Jump to: navigation, search A virus is a nonliving small particle that infects cells in biological organisms. ... A glycoprotein is a macromolecule composed of a protein and a carbohydrate (a sugar). ... A common alternate meaning of virus is computer virus. ...

Like rimantadine and amantadine, tromantadine is a derivate of adamantane. Rimantadine is an orally administered medicine used to treat, and in rare cases prevent, type A influenza. ... Jump to: navigation, search Amantadine, 1-aminoadamantane, is an antiviral drug that was approved by the FDA in 1976 for the treatment of influenza type A in adults. ... Adamantane (Tricyclo[3. ...

See also [1]

  Results from FactBites:
Welcome to | Brookes Pharmaceutical Laboratories (Pakistan) Limited | (492 words)
Tromantadine the first anti-viral ever developed which specifically inhibits the activity of herpes viruses Type-I Oral Type and Type-II Genital Type.
Tromantadine (Viru-Merz) is one of the several substances that were independently developed through the successful research efforts of Merz+ Co Germany.
Tromantadine, the active ingredient of Viru-Merz exerts its anti-viral effect on several steps of the viral activity cycle-without interfering with the genetic information of the host cell.
Patent 4174407: Antiviral agent (1105 words)
It is well known that the so-called "caged compounds" such as amantadine often show the anti RNA viral activites but rarely exhibit the anti DNA viral activities.
Among the caged compounds, only tromantadine is known to show an anti DNA viral activities.
The antiviral effects of the compound A on herpes virus and so on are much superior to those of tromantadine.
  More results at FactBites »



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