FACTOID # 21: 15% of Army recruits from South Dakota are Native American, which is roughly the same percentage for female Army recruits in the state.
 
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Encyclopedia > Transposase

Transposase is an enzyme that binds to single-stranded DNA and can incorporate it into genomic DNA. Class I transposons encode a transposase which allows them to enable transposons to be cut from genomic DNA and be inserted at another location. Ribbon diagram of the catalytically perfect enzyme TIM. Factor D enzyme crystal prevents the immune system from inappropriately running out of control. ... Transposons are sequences of DNA that can move around to different positions within the genome of a single cell, a process called Transposition. ...


  Results from FactBites:
 
Tania A. Baker (1255 words)
This domain is highly conserved among many transposases and the retroviral integrases.
These experiments led to two important conclusions: (1) the same catalytic domain donates the active site for both DNA cleavage and the subsequent DNA joining on one end of the genome, and (2) the subunit donating this catalytic domain to one end of the genome is bound to the other DNA end.
We are focusing on defining interactions between Mu transposase and its regulatory proteins, and probing how these interactions provide precision and flexibility to the recombination mechanism.
Tn5 Transposase (573 words)
Transposition is the movement of specific genetic elements from one locus to another (3), and requires three macromolecule elements: the transposon, the transposase, and the target DNA (4).
Mutations and modifications of the target affect binding of the transposase and IS50 DNA strand bending (5, 10).
Some modifications of the amino acid sequence affect the binding of transposase, the catalytic activity, or the stability of the transposase in a cell (1, 4, 8).
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