Transposase is an enzyme that binds to single-stranded DNA and can incorporate it into genomic DNA. Class I transposons encode a transposase which allows them to enable transposons to be cut from genomic DNA and be inserted at another location. Ribbon diagram of the catalytically perfect enzyme TIM. Factor D enzyme crystal prevents the immune system from inappropriately running out of control. ... Transposons are sequences of DNA that can move around to different positions within the genome of a single cell, a process called Transposition. ...
This domain is highly conserved among many transposases and the retroviral integrases.
These experiments led to two important conclusions: (1) the same catalytic domain donates the active site for both DNA cleavage and the subsequent DNA joining on one end of the genome, and (2) the subunit donating this catalytic domain to one end of the genome is bound to the other DNA end.
We are focusing on defining interactions between Mu transposase and its regulatory proteins, and probing how these interactions provide precision and flexibility to the recombination mechanism.
Share your thoughts, questions and commentary here
Want to know more? Search encyclopedia, statistics and forums:
Press Releases |
The Wikipedia article included on this page is licensed under the
Images may be subject to relevant owners' copyright.
All other elements are (c) copyright NationMaster.com 2003-5. All Rights Reserved.
Usage implies agreement with terms, 1022, m