Transfusion reactions occur after blood product transfusions when there is an interaction between the recipient and the donor blood. In addition to infections such as HIV and hepatitis, transfusions may result in fever, destruction of red blood cells (hemolysis) and allergic reactions. Less common but more serious reactions include transfusion related acute lung injury, transfusion-associated graft versus host disease, alloimmunization, and transfusion-related immunomodulation. Blood transfusion is the taking of blood or blood-based products from one individual and inserting them into the circulatory system of another. ... Human immunodeficiency virus (commonly known as HIV, and formerly known as HTLV-III and lymphadenopathy-associated virus) is a retrovirus that is the cause of the disease known as AIDS, or Acquired Immunodeficiency Syndrome, a syndrome where the immune system begins to fail, leading to many life-threatening opportunistic infections. ... Hepatitis is a gastroenterological disease, featuring inflammation of the liver. ... Hemolysis (alternative spelling haemolysis) literally means the excessive breakdown of red blood cells. ... An allergy can refer to several kinds of immune reactions including Type I hypersensitivity in which a persons body is hypersensitised and develops IgE type antibodies to typical proteins. ... Transfusion-associated graft versus host disease (TA-GvHD) is a rare complication of blood transfusion, in which the donor T lymphocytes mount an immune response against the recipients lymphoid tissue. ... Alloimmunity is a condition in which the body gains immunity against cells from another individual of the same species. ...
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ICD-10 Chapter T: World health Organisation classification - Complications following infusion, transfusion and therapeutic injection // S00-T98 - Injury, poisoning and certain other consequences of external causes (S00-S09) Injuries to the head (S00) Superficial injury of head (S01) Open wound of head (S02) Fracture of skull and facial bones (S03) Dislocation, sprain and strain of joints and ligaments of head (S04) Injury of cranial nerves...
^ Goodnough LT, Brecher ME, Kanter MH, AuBuchon JP. Transfusion medicine. First of two parts--blood transfusion. N Engl J Med. 1999 Feb 11;340(6):438-47. Review. PMID 9971869
Categories: Articles to be expanded | Transfusion medicine Transfusion medicine (or transfusiology) is the branch of medicine that is concerned with the transfusion of blood and blood components. ... Blood transfusion is the taking of blood or blood-based products from one individual and inserting them into the circulatory system of another. ... In medicine, Cross-matching refers to the process of performing blood tests to determine the similarity between two different blood types. ... Schematic showing the direct Coombs test and the indirect Coombs test. ... This article is being considered for deletion in accordance with Wikipedias deletion policy. ... The International Society of Blood Transfusion (ISBT) is a scientific society, founded in 1935, which aims to promote the study of blood transfusion, and to spread the know-how about the manner in which blood transfusion medicine and science best can serve the patients interests. ... ISBT 128 is system for identification, labeling and processing of human blood, tissue and organ products using an internationally standardised barcode system. ... Plateletpheresis (also called thrombapheresis or thrombocytapheresis) is a special type of blood donation that only extracts platelets, the cells that cause blood clotting, from the blood. ... The International Society of Blood Transfusion (ISBT) currently recognises 29 major blood group systems (including the ABO and Rh systems). ... A total of 29 human blood group systems are recognized by the International Society of Blood Transfusion (ISBT). ... The ABO system is the most important blood type system in human blood transfusion. ... The term Rhesus system refers to all of the antigens of the Rhesus blood group system - the five main rhesus antigens (C,c,D,E and e) as well as many other less frequent antigens. ... Discovery In 1950 the Duffy antigen was discovered in a multiply transfused hemophiliac in whose serum contained the first example of anti-Fya. ... Individuals with the rare Bombay phenotype (hh) do not express substance H (the antigen that defines blood group O) on their red blood cells, and therefore do not agglutinate (bind with) A or B antigens of the ABO blood group system. ... The Kell antigen system (also known as Kell-Cellano system) is a group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which destroy red blood cells. ... The Kidd antigen system (also known as Jk antigen) is present on the membranes of red blood cells and the kidney and helps determine a persons blood type. ... The Colton antigen system (Co) is present on the membranes of red blood cells and in the tubules of the kidney and helps determine a persons blood type. ... Blood donation is a process by which a blood donor voluntarily has blood drawn for storage in a blood bank or for subsequent use in a blood transfusion. ... Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ... Blood plasma is the liquid component of blood, in which the blood cells are suspended. ... A 250 ml bag of newly collected platelets. ... Cryoprecipitate is a blood product manufactured by warming frozen plasma. ... Plasmapheresis is the removal of (components of) blood plasma from the circulation. ... Human red blood cells Red blood cells are the most common type of blood cell and are the vertebrate bodys principal means of delivering oxygen from the lungs or gills to body tissues via the blood. ...
The evaluation of all adverse reactions to transfusion is the responsibility of the medical staff of the Blood Bank and the notification of such a reaction by the patient unit serves as a request for Blood Bank physician consultation.
Reactions may be separated into reactions that present in proximity to the transfusion and those that present at some time subsequent to the transfusion.
Supplemental transfusion of blood lacking the antigen corresponding to the offending antibody may be necessary to compensate for the transfused cells that have been removed from the circulation.
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