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Encyclopedia > Tissue factor
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Thromboplastin is a substance present in tissues, platelets, and leukocytes necessary for the coagulation of blood; in the presence of calcium ions thromboplastin is necessary for the conversion of prothrombin to thrombin, an important step in coagulation of blood. It is now generally believed that thromboplastin activity may be developed through blood (intrinsic) or tissue (extrinsic) systems. Tissue thromboplastin (factor III) interacts with factor VII and calcium to activate factor X; active factor X combines with factor V in the presence of calcium and phospholipid to produce thromboplastin activity (also commonly called thromboplastin). A 250 ml bag of newly collected platelets. ... White Blood Cells is also the name of a White Stripes album. ... The coagulation of blood is a complex process during which blood forms solid clots. ... Red blood cells (erythrocytes) are present in the blood and help carry oxygen to the rest of the cells in the body Blood is a circulating tissue composed of fluid plasma and cells (red blood cells, white blood cells, platelets). ... Jump to: navigation, search General Name, Symbol, Number calcium, Ca, 20 Chemical series alkaline earth metals Group, Period, Block 2, 4, s Appearance silvery white Atomic mass 40. ... Jump to: navigation, search An ion is an atom or group of atoms with a net electric charge. ... Thrombin (activated Factor II) is a coagulation protein that has many effects in the coagulation cascade. ... Thrombin (activated Factor II) is a coagulation protein that has many effects in the coagulation cascade. ...


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factor VII: Definition and Much More from Answers.com (576 words)
A factor in the clotting of blood that forms a complex with tissue thromboplastin and calcium to activate the prothrombinase, thus acting to accelerate the conversion of prothrombin to thrombin.
Tissue factor is found on the outside of blood vessels - normally not exposed to the bloodstream.
Factor VII is vitamin K dependent; it is produced in the liver.
Tissue factor - Wikipedia, the free encyclopedia (537 words)
Tissue factor, also called thromboplastin, factor III or CD142 is a protein present in subendothelial tissue, platelets, and leukocytes necessary for the initiation of thrombin formation from the zymogen prothrombin.
TF is the cell surface receptor for the serine protease factor VIIa.
Both pathways lead to the activation of factor X (the common pathway) which combines with activated factor V in the presence of calcium and phospholipid to produce thrombin (thromboplastin activity).
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