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Encyclopedia > Tabes dorsalis

Contents

Tabes dorsalis
Classifications and external resources
ICD-10 A52.1
ICD-9 094.0
DiseasesDB 29061
eMedicine neuro/684 
MeSH D013606

Tabes dorsalis is a slow degeneration of the nerve cells and nerve fibers that carry sensory information to the brain. The degenerating nerves are in the dorsal columns of the spinal cord (the portion closest to the back of the body) and carry information that help maintain a person's sense of position. The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) is a detailed description of known diseases and injuries. ... The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // A00-A79 - Bacterial infections, and other intestinal infectious diseases, and STDs (A00-A09) Intestinal infectious diseases (A00) Cholera (A01) Typhoid and paratyphoid fevers (A010) Typhoid fever (A02) Other Salmonella infections (A03) Shigellosis (A04) Other bacterial intestinal infections (A040) Enteropathogenic Escherichia coli infection (A045) Campylobacter enteritis (A046) Enteritis due to Yersinia... The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) is a detailed description of known diseases and injuries. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Diseases Database is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... Neurons (also called nerve cells) are the primary cells of the nervous system. ... In animals, the brain, or encephalon (Greek for in the head), is the control center of the central nervous system. ... The posterior horn (posterior column, posterior cornu, dorsal horn) of the spinal cord is dorsal (more towards the back) to the anterior horn. ... The Spinal cord nested in the vertebral column. ...


Cause

Tabes dorsalis is the result of an untreated syphilis infection. Syphilis is a sexually transmitted infection (STI) caused by a spirochaete bacterium, Treponema pallidum. ...


Symptoms

Symptoms may not appear for some decades after the initial infection and include weakness, diminished reflexes, unsteady gait (locomotor ataxia), progressive degeneration of the joints, loss of coordination, episodes of intense pain and disturbed sensation inclusive glossodynia, personality changes, dementia, deafness, visual impairment, and impaired response to light. Weakness can mean: The opposite of strength Weakness (medical) This is a disambiguation page — a navigational aid which lists pages that might otherwise share the same title. ... Tabes dorsalis (also called locomotor ataxia) is a late form of syphilis resulting in a degeneration of the dorsal columns of the spinal cord and marked by shooting pains, emaciation, loss of muscular coordination (resulting in the wide-based unsteady gait characteristic of the disease), and disturbances of sensation and... Glossodynia or burning mouth syndrome (BMS) is a condition characterized by a burning or tingling sensation on the lips, tongue, or entire mouth. ... There are other articles with similar names; see Dementia (disambiguation). ... An editor has expressed a concern that the topic of this article may be unencyclopedic. ... Visual impairment is the functional loss of vision. ...


Tabes dorsalgia is a related back pain.


Prognosis

If left untreated, tabes dorsalis can lead to paralysis, dementia, and blindness. Existing nerve damage cannot be reversed. Paralysis is the complete loss of muscle function for one or more muscle groups. ... There are other articles with similar names; see Dementia (disambiguation). ... Blindness is the condition of lacking visual perception due to physiological or psychological factors. ...


Incidence/Prevalence

The disease is more frequent in males than in females. Onset is commonly during mid-life. The incidence of tabes dorsalis is rising, in part due to co-associated HIV infection. Human immunodeficiency virus or HIV is a retrovirus that causes Acquired Immunodeficiency Syndrome (AIDS), a condition in which the immune system begins to fail, leading to life-threatening opportunistic infections. ...


Treatment

Penicillin, administered intravenously, is the treatment of choice. Associated pain can be treated with opiates, valproate, or carbamazepine. Patients may also require physical or rehabilitative therapy to deal with muscle wasting and weakness. Preventive treatment for those who come into sexual contact with an individual with tabes dorsalis is important. Penicillin nucleus Penicillin (sometimes abbreviated PCN) refers to a group of β-lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. ... An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ... The term opiate refers to the alkaloids found in opium, an extract from the seed pods of the opium poppy (). It has also traditionally referred to natural and semi-synthetic derivatives of morphine. ... Valproic acid or 2-Propylpentanoic acid is CH3CH2CH2CH(CH2CH2CH3)COOH . ... Carbamazepine (sold under the brand-names Biston, Calepsin, Carbatrol, Epitol, Equetro, Finlepsin, Sirtal, Stazepine, Tegretol, Telesmin, Timonil) is an anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy and bipolar disorder. ...


See also

General paresis, also known as general paralysis of the insane or paralytic dementia, is a now-rare neuropsychiatric disorder affecting the brain and central nervous system. ...

References


  Results from FactBites:
 
Tabes Dorsalis: Encyclopedia of Neurological Disorders (1851 words)
Tabes dorsalis is a late manifestation of untreated syphilis and is characterized by a triad of clinical symptoms namely gait unsteadiness, lightning pains and urinary incontinence.
Tabes dorsalis is more common in middle-aged males, homosexuals and inner city population in New York, San Francisco and the southern part of the United States.
There is no trial open for tabes dorsalis, but there is an ongoing phase III multicenter randomized trial as of early 2004 funded by the National Institute of Allergy and Infectious Diseases (NIAID) for assessing the antibiotic Azithromycin given orally in treatment of primary, secondary or early latent syphilis.
Tabes dorsalis - Wikipedia, the free encyclopedia (241 words)
Tabes dorsalis is a slow degeneration of the nerve cells and nerve fibers that carry sensory information to the brain.
Tabes dorsalis is the result of an untreated syphilis infection.
The incidence of tabes dorsalis is rising, in part due to co-associated HIV infection.
  More results at FactBites »

 
 

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