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Encyclopedia > Simmonds' disease
Simmonds' disease
Classifications and external resources
ICD-10 E23.0
DiseasesDB 11998
MeSH D007018

Simmonds' disease (also Simmonds' syndrome) refers to panhypopituitarism caused by the destruction of the pituitary gland due to infiltrative processes (e.g. lymphocytic), tumours (pituitary adenomas or craniopharyngiomas) or trauma (cranial injury or following surgery). The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other... The Diseases Database is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... Hypopituitarism is a medical term describing deficiency (hypo) of one or more hormones of the pituitary gland. ... The pituitary gland, or hypophysis, is an endocrine gland about the size of a pea that sits in a small, bony cavity (sella turcica) at the base of the brain. ... Pituitary adenomas are tumors that occur in the pituitary gland, and account for about 10% of intracranial neoplasms. ...


Sheehan's syndrome is a sub-classification of Simmond's disease occurring specifically in the peripartum period. Sheehan syndrome, also known as postpartum hypopituitarism or postpartum pituitary necrosis, is hypopituitarism (decreased functioning of the pituitary gland), caused by necrosis due to blood loss and hypovolemic shock during and after childbirth. ...


Eponym

It was first described by Morris Simmonds when a patient presented with 'fatal cachexia', although his patient went on to live for 11 more years. [1][2]


Symptoms

Although cachexia may be present, the disease is characterised by symptoms due to decreased gonadal, thyroidal and adrenal function. These include: ... In mammals, the adrenal glands are the triangle-shaped endocrine glands that sit atop the kidneys. ...

See Hypopituitarism Amenorrhoea (BE) or amenorrhea (AmE) is the absence of a menstrual period in a woman of reproductive age. ... Impotence or, more clinically, erectile dysfunction is the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. ... Libido in its common usage means sexual desire; however, more technical definitions, such as those found in the work of Carl Jung, are more general, referring to libido as the free creative--or psychic--energy an individual has to put toward personal development, or individuation. ... Fatigue is a feeling of excessive tiredness or lethargy, with a desire to rest, perhaps to sleep. ... In physiology and medicine, hypotension refers to an abnormally low blood pressure. ... Hypopituitarism is a medical term describing deficiency (hypo) of one or more hormones of the pituitary gland. ...


References

  1. ^ Simmonds M, (1914) Dtsch. med. Wschr. 40, 322
  2. ^ synd/2008 at Who Named It
  • Fraser R, Smith PH (1941) QJM. 10:297-330

 
 

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