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Encyclopedia > Rifaximin
Rifaximin Xifaxan
Rifaximin Xifaxan

Rifaximin is a nonabsorbable antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It is primarily used to treat diarrhea caused by E. coli, but recent studies published in the American Journal of Gastroenterology suggest its efficacy in relieving chronic functional symptoms of bloating and flatulence that are common in gastrointestinal disorders, such as Irritable Bowel Syndrome. Image File history File links Rifaximin_Xifaxan. ... An antibiotic is a drug that kills or slows the growth of bacteria. ... Binomial name Escherichia coli T. Escherich, 1885 E. coli at 10,000x magnification Escherichia coli, usually abbreviated to E. coli, discovered by Theodor Escherich, a pediatrician and bacteriologist, is one of the main species of bacteria that live in the lower intestines of warm-blooded animals, including birds and mammals. ...

It is currently sold under the brand name Xifaxan® by Salix Pharmaceuticals.


  • Sharara A, Aoun E, Abdul-Baki H, Mounzer R, Sidani S, ElHajj I. A Randomized Double-Blind Placebo-Controlled Trial of Rifaximin in Patients with Abdominal Bloating and Flatulence. The American Journal of Gastroenterology, 101(2):326 — February 2006.
  • Micromedex information on rifaximin
  • FDA label approved for Xifaxan (PDF warning)

February 2006 : ← - January - February - March - April - May - June - July - August - September - October - November - December- → 28 February 2006 (Tuesday) Al Askari Mosque bombing: Sixty-eight people have been killed so far today in Baghdad, Iraq. ...

External links

  • Xifaxan® (manufacturer's website)
  • Rifaximin (patient information)

  Results from FactBites:
RIFAXIMIN (4727 words)
Approximately 97% of an oral dose of rifaximin is recovered, primarily unchanged, in the feces and 0.32% is recovered in the urine.
Rifaximin 400 milligrams suspended in 200 to 400 milliliters (mL) sterile water administered via a nasogastric tube for 2 hours is recommended for patients with enterocolitis and bacterial superinfections causing intestinal inflammatory diseases and portosystemic encephalopathy (Alvisi et al, 1987).
Rifaximin 400 milligrams twice daily for 1 week every month was beneficial and well-tolerated in the treatment of diverticular disease and the prevention of its complications in 79 patients.
  More results at FactBites »



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