FACTOID # 5: Minnesota and Connecticut are both in the top 5 in saving money and total tax burden per capita.
 
 Home   Encyclopedia   Statistics   States A-Z   Flags   Maps   FAQ   About 
 
WHAT'S NEW
RELATED ARTICLES
People who viewed "Remifentanil" also viewed:
 

SEARCH ALL

FACTS & STATISTICS    Advanced view

Search encyclopedia, statistics and forums:

 

 

(* = Graphable)

 

 


Encyclopedia > Remifentanil
The structure of Remifentanil
The structure of Remifentanil

Remifentanil is a potent ultra short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anaesthetic. Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. Image File history File links Remifentanil. ... An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain and to achieve analgesia. ... Oral medication A medication is a licenced drug taken to cure or reduce symptoms of an illness or medical condition. ... Anesthesia (AE), also anaesthesia (BE), is the process of blocking the perception of pain and other sensations. ...

Contents


Dosing

It is administered in the form remifentanil hydrochloride and in adults is given as an intravenous infusion in doses ranging from 0.1 µg/kg/min to 0.5 µg/kg/min. Children may require higher infusion rates (up to 1.0 µg/kg/min) [Weale et al, 2004]. Doses listed in the package insert from its manufacturer are much higher than those used in actual clinical practice. The clinically useful infusion rates are 0.025-0.1 microgram/kg/min for sedation (rates adjusted to age of patient, severity of their illness and invasiveness of surgical procedure). Small amounts of other sedative medication are given along with the remifentanil to produce sedation. Clinically useful infusion rates in general anesthesia are similiar to those used for seadtion, except other potent medications are utlized aling with the Remifentanil in the case of general anesthesia.


Metabolism

Unlike other synthetic opioids, its clearance is dependent on non-specific plasma esterases. This means that accumulation does not occur with remifentanil and its context-sensitive half-life remains at 4 minutes after a 4 hour infusion. Acetylcholinesterase In biochemistry, cholinesterase is a term which refers to one of the two enzymes: Acetylcholinesterase (EC 3. ...


Remifentanil is metabolised to a compound (remifentanil acid) which has 1/1600 the potency of the parent compound.


Side-effects

Remifentanil is a specific μ-receptor agonist. Hence, it causes a reduction in sympathetic nervous system tone, respiratory depression and analgesia. The drug's effects include a dose-dependent decrease in heart rate and arterial pressure and respiratory rate and tidal volume. Muscle rigidity is sometimes noted. Heart rate is a term used to describe the frequency of the cardiac cycle. ... Blood pressure is the pressure exerted by the blood on the walls of the blood vessels. ... Wikipedia does not have an article with this exact name. ... The average pair of human lungs can hold about 6 litres of air, but only a small amount is used during normal breathing. ...


References

  • Abbott Laboratories, Chicago, IL "'Ultiva"' package insert
  • Weale NK, Rogers CA, Cooper R, Nolan J, Wolf AR. Effect of remifentanil infusion rate on stress response to the pre-bypass phase of paediatric cardiac surgery.Br J Anaesth. 2004 Feb;92(2):187-94.


Analgesics edit

{Paracetamol (acetaminophen)} {NSAIDs} {Opiates} {Tetrahydrocannabinol} An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain and to achieve analgesia. ... Paracetamol (INN) (IPA: ) or acetaminophen (USAN) is a common analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Wikipedia does not yet have an article with this exact name. ... An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... Tetrahydrocannabinol, also known as THC, Δ9-THC, Δ9-tetrahydrocannabinol (delta-9-tetrahydrocannabinol), Δ¹-tetrahydrocannabinol (using an older numbering scheme), or dronabinol, is the main psychoactive substance found in the Cannabis plant. ...

NSAIDs edit

{Aspirin} {Celecoxib} {Diclofenac} {Diflunisal} {flurbiprofen} {Ibuprofen} {Indomethacin} {Ketoprofen} {Ketorolac} {Meloxicam} {Naproxen} {Piroxicam} {Rofecoxib} {Valdecoxib} Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Aspirin or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum growths polyps in patients with familial adenomatous polyposis. ... Diclofenac (marketed as Voltaren®, Voltarol®, Diclon® and Cataflam®) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation, such as in arthritis or acute injury. ... Diflunisal is a generic NSAID (Non Steroidal Anti Inflammatory Drug). ... Flurbiprofen is an NSAID (non-steroidal anti-inflammatory drug) used to treat the inflammation and pain of arthritis. ... Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely marketed under various trademarks including Act-3, Advil, Brufen, Motrin, Nuprin, and Nurofen. ... Indomethacin (USAN) or indometacin (INN) is a non-steroidal anti-inflammatory drug commonly used to reduce fever, pain, stiffness, and swelling. ... Ketoprofen, 2-(3-benzoylphenyl)-propionic acid (chemical formula C12H12O2) is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with additional analgesic and anti-pyretic effects. ... Ketorolac or ketorolac tromethamine (marketed as Toradol® - generics have been approved) is a non-steroidal anti-inflammatory drug (NSAID) in the family of propionic acids, often used as an analgesic, antipyretic (fever reducer), and anti-inflammatory. ... Meloxicam is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ... Naproxen (trade names: Aleve, Anaprox, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the treatment... Piroxicam (US trade name Feldene) is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ... Rofecoxib (IPA: ) is a nonsteroidal anti-inflammatory drug (NSAID) that was used in the treatment of osteoarthritis, acute pain conditions, and dysmenorrhoea. ... Valdecoxib is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. ...

Opioids edit

{Alfentanil} {Buprenorphine} {Carfentanil} {Codeine} {Codeinone} {Dextropropoxyphene} {Diamorphine (Heroin)} {Dihydrocodeine} {Fentanyl} {Hydrocodone} {Hydromorphone} {Methadone} {Morphine} {Morphinone} {Nalbuphine} {Oxycodone} {Oxymorphone} {Pentazocine} {Pethidine (Meperidine)} {Propoxyphene} {Remifentanil} {Sufentanil} {Tramadol} An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... Alfentanil (Alfenta) is a parenteral short-acting opioid painkiller, used for anaesthesia in surgery. ... Buprenorphine, also colloquially referred to as bupe, is an opioid drug with partial agonist and antagonist actions. ... Carfentanil, also Carfentanyl, is an analogue of the popular opioid Fentanyl, and is currently the most potent opioid known [Actually Ohmefentanil is 13,000X morphine]. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl (activity in humans starting at about 1... Codeine (INN) or methylmorphine is an opioid used for its analgesic, antitussive and antidiarrheal properties. ... Codeinone is a strong Opiod. ... Dextropropoxyphene is an analgesic in the opioid category. ... Heroin or diacetylmorphine (INN) is a semi-synthetic opioid. ... Dihydrocodeine, also called DHC or DF-118, is a synthetic opioid analgesic prescribed for postoperative pain, severe dyspnea, or as an antitussive. ... Fentanyl is an opioid analgesic, first synthesized in Belgium in the late 1950s, with an analgesic potency of about 80 times that of morphine. ... Hydrocodone or dihydrocodeinone (marketed as Vicodin, Anexsia, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Tussionex, Vicoprofen) is an opioid derived from either of the naturally occurring opiates codeine or thebaine. ... // Overview Hydromorphone is a drug used to relieve moderate to severe pain. ... Methadone is a synthetic opioid analgesic synthesized in 1937 by German scientists Max Bockmühl and Gustav Ehrhart at IG Farben (Hoechst-Am-Main) who were searching for an analgesic that would be easier to use during surgery and also have low addiction potential. ... See Morphia for the Dutch metal band. ... Morphinone is a very strong Opiod. ... Nalbuphine (nalbuphine hydrochloride) is a synthetic opioid used commercially as an analgesic under a variety of trade names, including Nubain. ... Oxycodone is a very powerful and potentially addictive opioid analgesic medication synthesized from thebaine. ... Oxymorphone is a powerful synthetic narcotic analgesic drug that is similar to morphine. ... Pentazocine is a synthetically-prepared narcotic drug used to treat mild to moderate pain. ... Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; operidine; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ... Dextropropoxyphene is an analgesic in the opioid category that is used to treat severe pain and severe coughs. ... Sufentanil is a drug that belongs to the class of drugs known as the opioid analgesic drugs. ... Tramadol is an opioid used as an analgesic for treating moderate to severe pain. ...


 
 

COMMENTARY     


Share your thoughts, questions and commentary here
Your name
Your comments

Want to know more?
Search encyclopedia, statistics and forums:

 


Press Releases |  Feeds | Contact
The Wikipedia article included on this page is licensed under the GFDL.
Images may be subject to relevant owners' copyright.
All other elements are (c) copyright NationMaster.com 2003-5. All Rights Reserved.
Usage implies agreement with terms, 1022, m