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Encyclopedia > Reflux nephropathy
Reflux nephropathy
Classification & external resources
ICD-9 593.73
DiseasesDB 11209
MedlinePlus 000459
eMedicine radio/597 

Reflux nephropathy, RN is a term applied when small and scarred kidneys (chronic pyelonephritis, CPN) are associated with vesico-ureteric reflux (VUR). CPN being the commonest cause, there are other causes including analgesic nephropathy and obstructive injury. Scarring is essential in developing RN and occurs almost during the first five years of life. The end results of RN are hypertension, proteinuria, CRF and eventually ESRD, end stage renal disease. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... MedlinePlus (medlineplus. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Pyelonephritis is an ascending urinary tract infection that has reached the pyelum (pelvis) of the kidney (nephros in Greek). ... This article or section does not cite any references or sources. ... Proteinuria (from protein and urine) means the presence of an excess of serum proteins in the urine. ... Chronic renal failure - Wikipedia /**/ @import /skins/monobook/IE50Fixes. ...


Diagnosis

It is diagnosed by micturating cystography, scarring can of course be demonstrated by ultrasound or DMSA. Ultrasound is a form of cyclic sound pressure with a frequency greater than the upper limit of human hearing, this limit being approximately 20 kilohertz (20,000 hertz). ... DMSA or dimercaptosuccinic acid is a chelating agent. ...


Incidence/prevalence

There is a genetic predisposition, first-degree relatives have a great increase in the chance of VUR.


The gene frequency is estimated to be 1:600. All children with UTI should be investigated for VUR.


Treatment

The aim of treatment is to reduce renal scarring. Those children with grade II or worse should receive low dose prophylactic antibiotics (Nitrofurantoin, trimethoprim, cotrimoxazole, cefalexin in those with CRF). Hypertension should be managed with ACE or ARB's. Other treatment modalities also include surgery ( endoscopic injection of collagen behind the intra-vesical ureter, ureteric re-implantation or lengthening of the submucosal ureteric tunnel) which has its protagonists. This page is a candidate to be moved to Wiktionary. ... Staphylococcus aureus - Antibiotics test plate. ... Nitrofurantoin is an antibiotic. ... Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections (cystitis). ... Co-trimoxazole (abbreviated SXT, TMP-SMX, or TMP-sulfa) is an antibiotic combination of trimethoprim and sulfamethoxazole, in the ratio of 1 to 5, used in the treatment of a variety of bacterial infections. ... Cefalexin (INN) (IPA: ) or cephalexin (USAN) is a first-generation cephalosporin antibiotic. ... Ace cards of all four suits The word ace comes from the Old French word as (from Latin as) meaning a unit, from the name of a small Roman coin. ... ARB is a three-letter acronym that may stand for: Accident Report Book (UK) Adaptive rate-based (congestion control) Africa Research Bulletin Air Reserve base Air Resources Board (California) American Research Bureau The IATA airport code for the Ann Arbor, Michigan airport Amtraks 3-letter code for the rail...


 
 

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