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Encyclopedia > Rapid Plasma Reagin

Rapid Plasma Reagin, a modern screening test for antibodies in the serum of patients with syphilis. Syphilis (historically called lues) is a sexually transmitted disease (STD) that is caused by a spirochaete bacterium, Treponema pallidum. ...

  Results from FactBites:
- Northwestern Memorial Hospital - Chicago (733 words)
The RPR screening test is similar to the older VDRL test as both measure reaginic antibodies.
These antibodies are usually produced during infection with syphilis as a result of the body's interaction with the bacteria which causes syphilis (Treponema pallidum).
The RPR test may be used not only for screening, but for monitoring the effect of antibiotic therapy for syphilis.
Summary West et al Performance of the rapid plasma...Articles for review.Literature review.Sexually Transmitted ... (620 words)
Rapid plasma reagin and rapid syphilis screening tests do not perform well for the diagnosis of syphilis in field conditions.
The performance of the field RPR and RST tests against serologically active syphilis (defined by laboratory RPR positive and TPHA positive) is shown in the table.
In a direct comparison of RPR results on 1295 samples tested both in the field and in the laboratory, there was agreement on 1207 negative and 35 positive samples, while 41 samples were positive in the field but negative in the laboratory and 12 were negative in the field and positive in the laboratory.
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