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Encyclopedia > Pyrovalerone

Pyrovalerone (Centroton, Thymergix) is a stimulant drug developed in the late 1960s and used in France and some other European countries. This drug is now rarely prescribed due to problems with abuse and dependence [1] , but is still rarely prescribed either as an appetite suppresant or for treating chronic fatigue and lethargy. [2] Side effects of pyrovalerone include loss of appetite, anxiety, insomnia and tremor. Withdrawal sydrome following abuse causes depression. [3] Pyrovalerone is a Schedule 5 drug in the USA. Stimulants are drugs that increase alertness and wakefulness. ... Fatigue is a feeling of excessive tiredness or lethargy, with a desire to rest, perhaps to sleep. ... Anorexia (deriving from the Greek όρεξη (orexe) = appetite) is the decreased sensation of appetite. ... Anxiety is an unpleasant complex combination of emotions that includes fear, apprehension and worry, and is often accompanied by physical sensations such as palpitations, nausea, chest pain and/or shortness of breath. ... For other uses, see Insomnia (disambiguation). ... For the film see Tremors (film). ... Depression, or a depressed mood, may in everyday English refer to a state of melancholia, unhappiness or sadness, or to a relatively minor downturn in mood that may last only a few hours or days. ...


Image:pyrovalerone.png


1-(4-methylphenyl)-2-(1-pyrrolidinyl)pentan-1-one


CAS# 1147-62-2 (pyrovalerone hydrochloride); 3563-49-3 (pyrovalerone freebase)


References

  1. ^ Deniker P, Loo H, Cuche H, Roux JM. Abuse of pyrovalerone by drug addicts. Annales Medico-Psychologiques (Paris) 1975 Nov;2(4):745-8.
  2. ^ Gardos G, Cole JO. Evaluation of pyrovalerone in chronically fatigued volunteers. Current Therapeutic Research, Clinical and Experimental. 1971 Oct;13(10):631-5.
  3. ^ http://www.biam2.org/www/Etr8623.html



[edit]Stimulants -

Adrafinil, Amphetamine (speed), Armodafinil, Caffeine, Cocaine, Ephedrine, Epinephrine (adrenaline), Modafinil, Nicotine, Stimulants are drugs that increase alertness and wakefulness. ... Adrafinil chemical structure Adrafinil is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention in elderly patients. ... Amphetamine (alpha-methyl-phenethylamine), also known as speed whiffles, is a stimulant, and club drug, used to diminish the appetite, control weight, and treat disorders including narcolepsy and attention-deficit hyperactivity disorder. ... Armodafinil (Nuvigil®) is a drug produced by the pharmaceutical company Cephalon, currently in the process of receiving FDA approval. ... Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. ... Cocaine (or crack in its impure freebase form) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. ... Ephedrine (EPH) is a sympathomimetic amine similar in structure to the synthetic derivatives amphetamine and methamphetamine. ... Adrenaline redirects here. ... Modafinil (commercial trade names Provigil (US, UK, Italy), Vigil (Germany), Modalert (India), Modiodal (France, Mexico, Turkey), Modavigil (Australia), Alertec (Canada), and possibly Vigicer) is a eugeroic drug generally prescribed to treat narcolepsy, made by the pharmaceutical company Cephalon Inc. ... Not to be confused with Niacin, which is the oxide of Nicotine, and has a very different biological effect. ...




[edit]Sympathomimetic amines (R01, A08, and others)

Alpha-pyrrolidinopropiophenone, Aminorex, Amphetamine, Benzylpiperazine, Cathinone, CFT, Chlorphentermine, Clobenzorex, Cocaine, Cyclopentamine, Diethylpropion, Ephedrine, 4-FMP, 4-MTA, Fencamfamine, Fenfluramine, Mazindol, MDPV, 4-Methyl-aminorex, Methylone, Methylphenidate, Pemoline, Phendimetrazine, Phenmetrazine, Phentermine, Phenylephrine, Propylhexedrine, Pseudoephedrine, Pyrovalerone, Sibutramine, Synephrine Sympathomimetic drugs are substances that mimic the effects of the hormone adrenaline. ... A section of the Anatomical Therapeutic Chemical Classification System. ... A division of the Anatomical Therapeutic Chemical Classification System A Alimentary tract and metabolism A08A Antiobesity preparations, excluding diet products A08AA Centrally acting antiobesity products A08AA01 Phentermine A08AA02 Fenfluramine A08AA03 Amfepramone A08AA04 Dexfenfluramine A08AA05 Mazindol A08AA06 Etilamfetamine A08AA07 Cathine A08AA08 Clobenzorex A08AA09 Mefenorex A08AA10 Sibutramine A08AA56 Ephedrine, combinations A08AB Peripherally... Alpha-pyrrolidinopropiophenone (α-PPP) is a stimulant drug. ... Wikipedia does not yet have an article with this exact name. ... Amphetamine (alpha-methyl-phenethylamine), also known as speed whiffles, is a stimulant, and club drug, used to diminish the appetite, control weight, and treat disorders including narcolepsy and attention-deficit hyperactivity disorder. ... Benzylpiperazine (BZP) is a recreational drug with euphoric, stimulant effects. ... Cathinone (β-ketoamphetamine) is a monoamine alkaloid found in the shrub Catha edulis (Khat). ... (-)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane naphthalenedisulfonate (CFT) is a dopamine reuptake inhibitor structurally similar to cocaine. ... Chlorphentermine (Apsedon, Desopimon, Lucofen) is a stimulant drug which was used as an appetite suppressant. ... Clobenzorex (also known under the brand names Asenlix, Finedal, or Rexigen; or the US slang greenies) is a stimulant drug used as an anorectic (that is, a medication that suppresses appetite). ... Cocaine (or crack in its impure freebase form) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. ... Cyclopentamine is a stimulant drug structurally related to methamphetamine, wherein the aromatic phenyl ring is replaced with a cyclopentane ring. ... Diethylpropion (Tenuate®) is a sympathomimetic stimulant drug marketed as an appetite suppressant. ... Ephedrine (EPH) is a sympathomimetic amine similar in structure to the synthetic derivatives amphetamine and methamphetamine. ... 4-FMP molecular structure 4-FMP 4-FMP, also known by its full chemical name 4-fluoroamphetamine, or 4-Fluoro-alpha-Methyl-Phenethylamine, is a central nervous system stimulant. ... 4MT structure 4-methylthioamphetamine is a drug known as 4MT, 4-MTA, Flatliners, 1-(4-methylthiophenyl)-2-aminopropane. ... Fencamfamine (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite supressant, but was later withdrawn for this application due to problems with dependence and abuse. ... Fenfluramine is a drug that was part of the Fen-Phen anti-obesity (the other drug being phentermine). ... This page may meet Wikipedia’s criteria for speedy deletion. ... 4-Methylaminorex is a stimulant drug of the 2-Amino-5-Aryloxazoline class. ... Methylone is a designer drug that is an analog of MDMA (Ecstasy). ... Methylphenidate (MPH) is an amphetamine-like prescription stimulant commonly used to treat Attention Deficit Hyperactivity Disorder (ADHD) in children and adults. ... Pemoline is a medication for Attention-deficit hyperactivity disorder (ADHD). ... Phendimetrazine (Bontril®) is a weight loss medication. ... Phenmetrazine is an amphetamine-like drug. ... Phentermine is a drug primarily used as an appetite suppressant. ... Phenylephrine or neosynephrine is an α-adrenergic receptor agonist used primarily as a decongestant, as an agent to dilate the pupil and, rarely, to increase blood pressure. ... Basics: Propylhexedrine is an over-the-counter nasal decongestant found in Benzedrex nasal inhalers. ... Pseudoephedrine (commonly abbreviated as PSE) is a sympathomimetic amine commonly used as a decongestant. ... Sibutramine (Meridia® in the USA, Reductil® in Europe), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. ... Synephrine Synephrine is a dietary supplement aimed at encouraging fat loss. ...


See also amphetamines Amphetamine (alpha-methyl-phenethylamine), also known as speed whiffles, is a stimulant, and club drug, used to diminish the appetite, control weight, and treat disorders including narcolepsy and attention-deficit hyperactivity disorder. ...


 
 

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