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Encyclopedia > Presynaptic

In a synapse between two neurons, the cell that releases the neurotransmitter is referred to as the presynaptic cell. Illustration of the major elements in a prototypical synapse. ... Neurons (also spelled neurones or called nerve cells) are the primary cells of the nervous system. ... Neurotransmitters are chemicals that are used to relay, amplify and modulate electrical signals between a neuron and another cell. ...

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Lambert-Eaton-Syndrome (1239 words)
The primary physiological disorder in the Lambert-Eaton myasthenic syndrome (LEMS) is a reduced release of the neurotransmitter acetylcholine from the nerve terminals into the synaptic gap.
This presynaptic disorder is caused by autoantibodies against a membrane protein of the nerve cell, the voltage-gated calcium channel (VGCC).
A transient depolarization of the presynaptic membrane causes the opening of the voltage-gated calcium channels, which allows the local influx of calcium ions into the nerve terminal.
Endogenous regulators of G protein signaling proteins regulate presynaptic inhibition at rat hippocampal synapses -- ... (4026 words)
Percent presynaptic inhibition was calculated as the difference between peak EPSC amplitudes under control conditions and in the presence of the drug divided by the control EPSC amplitude, multiplied by 100.
neurons, adenosine-induced presynaptic inhibition was 59 ± 6%,
that the onset of adenosine-induced presynaptic inhibition was
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