StateMaster - Encyclopedia: Piroxicam

Piroxicam (marketed in the U.S. under the trade name Feldene) is a non-steroidal anti-inflammatory drug used to relieve the symptoms of Rheumatoid and Osteoarthritis, primary dysmenorrhoea, Post Operative Pain; and act as an analgesic, especially where there is an inflammatory component. It is also used in veterinary medicine to treat certain neoplasias expressing cyclooxygenase (COX) receptors, such as bladder, colon, and prostate cancers. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Arthritis (from Greek arthro-, joint + -itis, inflammation; plural: arthritides) is a group of conditions where there is damage caused to the joints of the body. ... Dysmenorrhea (or dysmenorrhoea), cramps or painful menstruation, involves menstrual periods that are accompanied by either sharp, intermittent pain or dull, aching pain, usually in the pelvis or lower abdomen. ... An analgesic (colloquially known as a painkiller) is any member of the diverse group of drugs used to relieve pain (achieve analgesia). ... An abscess on the skin, showing the redness and swelling characteristic of inflammation. ... Veterinary medicine is the application of medical, diagnostic, and therapeutic principles to companion, domestic, exotic, wildlife, and production animals. ... Neoplasia (new growth in Greek) is abnormal proliferation of cells in a tissue or organ. ... Cyclooxygenase (COX) is an enzyme (EC 1. ... In anatomy, the urinary bladder is a hollow, muscular, and distensible (or elastic) organ that sits on the pelvic floor in mammals. ... For the article about the punctuation symbol, see Colon (punctuation). ... The prostate is a compound tubuloalveolar exocrine gland of the male mammalian reproductive system. ... Cancer is a class of diseases or disorders characterized by uncontrolled division of cells and the ability of these to spread, either by direct growth into adjacent tissue through invasion, or by implantation into distant sites by metastasis (where cancer cells are transported through the bloodstream or lymphatic system). ...

Mechanism of action

Piroxicam is an NSAID and, as such, is a non-selective COX inhibitor possessing both analgesic and antipyretic properties. It undergoes entero-hepatic circulation. Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Cyclooxygenase (COX) is an enzyme (EC 1. ...

Adverse effects

Piroxicam use can result in gastrointestinal toxicity, tinnitus, dizziness, headache, rash, and pruritus. The most severe adverse reactions are peptic ulceration and gastrointestinal bleeding. Approximately 30% of all patients receiving daily doses of 20 mg of piroxicam experience side effects.^[1]
Doctors in the USA do not like Piroxicam due to possible law suits but if this is the only drug that works for you (i.e. for gout) press for it and sign a disclaimer if needed.
Piroxicam may cause your skin to become more sensitive to sunlight. Try to avoid sunlight (UV) and use a sun protection cream until you know how your skin reacts.
The pack will come with a long list of possible unwanted side effects. Daily doses range from 10mg to 40mg in most cases. Due to the above adverse effects, start will a lower dose (use a pill spliter if required) and work up to daily doseage. Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... For the Physics term GUT, please refer to Grand unification theory The gastrointestinal or digestive tract, also referred to as the GI tract or the alimentary canal or the gut, is the system of organs within multicellular animals which takes in food, digests it to extract energy and nutrients, and... Tinnitus (IPA pronunciation: or ,[1] from the Latin word for ringing[2]) is the perception of sound in the human ear in the absence of corresponding external sound(s). ... // Pre-syncope is a sensation of feeling faint. ... A headache (cephalalgia in medical terminology) is a condition of pain in the head; sometimes neck or upper back pain may also be interpreted as a headache. ... A rash is a change in skin which affects its color, appearance or texture. ... An itch (Latin: pruritus) is a sensation felt on an area of skin that makes a person or animal want to scratch it. ... A benign gastric ulcer (from the antrum) of a gastrectomy specimen. ...

Footnotes

v • d • e

Non-steroidal anti-inflammatory drugs (primarily M01A and M02A, also N02BA)

Salicylates: Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide, Salicin For the Manfred Mann album, see 2006 (album). ... September 10 is the 253rd day of the Gregorian calendar (254th in leap years). ... Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... A section of the Anatomical Therapeutic Chemical Classification System. ... A section of the Anatomical Therapeutic Chemical Classification System. ... A section of the Anatomical Therapeutic Chemical Classification System. ... Aspirin, or acetylsalicylic acid (IPA: ), (acetosal) is a drug in the family of salicylates, often used as an analgesic (to relieve minor aches and pains), antipyretic (to reduce fever), and as an anti-inflammatory. ... Diflunisal is a generic NSAID (Non Steroidal Anti Inflammatory Drug). ... Ethenzamide is a common analgesic and antiinflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Salicylic acid is a colorless, crystalline organic carboxylic acid. ...

Arylalkanoic acids: Diclofenac, Etodolac, Indometacin, Nabumetone, Sulindac Diclofenac (marketed as VoltarenÂ®, VoltarolÂ®, DiclonÂ®, DicloflexÂ® Difen and CataflamÂ®) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and an analgesic reducing pain in conditions such as in arthritis or acute injury. ... Etodolac is the International Nonproprietary Name (INN) of 1,8-diethyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acid (empirical formula C17H21NO3), also sold under the trade name Lodine. ... Indomethacin is an indole derived non-steroidal anti-inflammatory drug. ... Nabumetone is a non-steroidal anti-inflammatory drug of the arylalkanoic acid family (which includes diclofenac. ... Sulindac is a non-steroidal anti-inflammatory drug of the arylalkanoic acid class that is marketed in the U.S. as Clinoril. ...

2-Arylpropionic acids (profens): Carprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Ketorolac, Loxoprofen, Naproxen, Suprofen, Tiaprofenic acid Carprofen is a non-steroidal anti-inflammatory drug that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. ... Flurbiprofen is an NSAID (non-steroidal anti-inflammatory drug) used to treat the inflammation and pain of arthritis. ... Ibuprofen (INN) (IPA: ) is a non-steroidal anti-inflammatory drug (NSAIDs) originally marketed as Nurofen and since under various trademarks including Act-3, Advil, Brufen, Dorival, Herron Blue, Panafen, Motrin, Nuprin and Ipren or Ibumetin (Sweden), Ibuprom (Poland), IbuHEXAL, Moment (Italy), Ibux (Norway). ... Ketoprofen, (RS)2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. ... Ketorolac or ketorolac tromethamine (marketed as ToradolÂ® - generics have been approved) is a non-steroidal anti-inflammatory drug (NSAID) in the family of propionic acids, often used as an analgesic, antipyretic (fever reducer), and anti-inflammatory. ... Loxoprofen (INN) is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group. ... Naproxen (trade names: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the... Suprofen is an NSAID marketed in a 1% solution under the trade name Profenal. ... Tiaprofenic acid is pharmaceutical, belonging to the class called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to treat pain, especially arthritic pain. ...

N-Arylanthranilic acids (fenamic acids): Mefenamic acid This article needs to be cleaned up to conform to a higher standard of quality. ...

Pyrazolidine derivatives: Phenylbutazone Phenylbutazone, often known as bute, is a crystalline substance having the structure shown at right. ...

Oxicams: Meloxicam, Piroxicam Meloxicam is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ...

Coxibs: Celecoxib, Etoricoxib, Parecoxib, Rofecoxib, Valdecoxib Celecoxib (INN) (IPA: ) is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. ... Etoricoxib (brand name Arcoxia®) is a new COX-2 selective inhibitor from Merck & Co. ... Injectible prodrug of valdecoxib. ... Rofecoxib (IPA: ) is a nonsteroidal anti-inflammatory drug (NSAID) developed by Merck & Co. ... Valdecoxib is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. ...

Sulphonanilides: Nimesulide Nimesulide structure formula Nimesulide is a prescription non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. ...

Topically used products: Diclofenac, Flurbiprofen, Ibuprofen, Indometacin, Ketoprofen, Naproxen, Piroxicam, Suprofen Diclofenac (marketed as VoltarenÂ®, VoltarolÂ®, DiclonÂ®, DicloflexÂ® Difen and CataflamÂ®) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and an analgesic reducing pain in conditions such as in arthritis or acute injury. ... Flurbiprofen is an NSAID (non-steroidal anti-inflammatory drug) used to treat the inflammation and pain of arthritis. ... Ibuprofen (INN) (IPA: ) is a non-steroidal anti-inflammatory drug (NSAIDs) originally marketed as Nurofen and since under various trademarks including Act-3, Advil, Brufen, Dorival, Herron Blue, Panafen, Motrin, Nuprin and Ipren or Ibumetin (Sweden), Ibuprom (Poland), IbuHEXAL, Moment (Italy), Ibux (Norway). ... Indomethacin is an indole derived non-steroidal anti-inflammatory drug. ... Ketoprofen, (RS)2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. ... Naproxen (trade names: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the... Suprofen is an NSAID marketed in a 1% solution under the trade name Profenal. ...