It has been suggested that this article or section be merged with Interferon. (Discuss)
Pegylated Interferon Alpha Wikipedia does not have an article with this exact name. ... Jump to: navigation, search Interferons (IFNs) are natural proteins produced by the cells of the immune systems of most animals in response to challenges by foreign agents such as viruses, bacteria, parasites and tumor cells. ...
There are currently 2 Pegylated Interferon alpha medicines available in the market: Pegasys - pegylated interferon alpha-2a marketed by Roche and PegIntron - pegylated interferon alpha-2b marketed by Schering-Plough. They are both licenced to treat Chronic Hepatitis C alone or in combination therapy with ribavirin. Jump to: navigation, search Hepatitis C is a form of hepatitis liver inflammation caused by a virus, the Hepatitis C virus (HCV). ... Ribavirin (CopegusÂ®; RebetolÂ®) is an anti-viral drug active against a number of DNA and RNA viruses. ...
Interferons (IFNs) are natural proteins produced by the cells of the immune systems of most animals in response to challenges by foreign agents such as viruses, bacteria, parasites and tumor cells.
Interferon was scarce and expensive until 1980 when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing mass cultivation and purification from bacterial cultures.
Used in combination with the antiviral drug ribavirin, pegylatedinterferon produces sustained cure rates of 75% or better in people with genotype 2 or 3 hepatitis C (which is easier to treat) and about 50% in people with genotype 1 (which is most common in the U.S. and Western Europe).
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