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Encyclopedia > Pancytopenia
Pancytopenia
Classification & external resources
ICD-10 D61.0, R79.1
ICD-9 284.0, 284.8

Pancytopenia is a medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... medicines, see Medication. ... Human red blood cells Red blood cells are the most common type of blood cell and the vertebrate bodys principal means of delivering oxygen from the lungs or gills to body tissues via the blood. ... A scanning electron microscope image of normal circulating human blood. ... A 250 ml bag of newly collected platelets. ...


Pancytopenia is generally due to diseases affecting the bone marrow, although peripheral destruction of all lines of blood cells in hypersplenism (overactive spleen) is a recognised cause. Bone marrow problems causing pancytopenia include myelofibrosis, leukemia, aplastic anemia, and the malignant form of osteopetrosis. Grays Anatomy illustration of cells in bone marrow. ... Splenomegaly is an enlargement of the spleen, which usually lies in the left upper quadrant (LUQ) of the human abdomen. ... Myelofibrosis with myeloid metaplasia, also known as agnogenic myeloid metaplasia, chronic idiopathic myelofibrosis, and primary myelofibrosis,[1] was first described in 1879 and is currently classified as a myeloproliferative disease caused by the growth and proliferation of an abnormal bone marrow stem cell, resulting in the replacement of the bone... Leukemia or leukaemia (see spelling differences) is a cancer of the blood or bone marrow and is characterized by an abnormal proliferation (production by multiplication) of blood cells, usually white blood cells (leukocytes). ... Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. ...


Increasingly, HIV (Human Immunodeficiency Virus) is itself a cause for pancytopenia. Rarely, drugs (antibiotics, blood pressure medication, heart medication) can cause pancytopenia.


Pancytopenia usually requires a bone marrow biopsy in order to distinguish among different causes.


Causes of pancytopenia

1. Aplastic anemia 2. Myelodysplastic syndrome 3. Leukemia 4. Severe Folate or Vitamin B12 deficiency 5. Paroxysmal nocturnal hemoglobinuria (Urine test) 6. Finally overwhelming viral infections (HIV most common). Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. ... Leukemia or leukaemia (see spelling differences) is a cancer of the blood or bone marrow and is characterized by an abnormal proliferation (production by multiplication) of blood cells, usually white blood cells (leukocytes). ...


See also


 
 

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