For other uses of painkiller, see painkiller (disambiguation)
An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain. Analgesic drugs include the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, narcotic drugs such as morphine, and synthetic drugs with narcotic properties such as tramadol. Other classes of drugs not normally considered analgesics are used to treat neuropathic pain syndromes; these include tricyclic antidepressants and anticonvulsants.
NSAIDs such as aspirin, naproxen, and ibuprofen not only relieve pain but also reduce fever and inflammation. Narcotic analgesics such as opiates and opioids largely work through specific opioid receptors in the central nervous system and alter the perception of pain (nociception). They are used to alleviate pain not relieved by the NSAIDs.
Analgesics are frequently used in combination, such as the paracetamol (acetaminophen) and codeine preparations found in many non-prescription pain relievers. They can also be found in combination with vasoconstrictor drugs such as pseudoephedrine for sinus-related preparations, or with antihistamine drugs for allergy sufferers.
Painkiller is a pure first person action shooter supported by an adventure-based plot and is currently being developed for the PC.
Players take on the role of Painkiller, an unusual mercenary who makes a living by exorcising vampires and other dreadful beasts from their lairs- abandoned prisons, private castles, deep caves in the mountains, extravagant haciendas hidden in the jungle.
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Painkiller was something of a surprise hit in 2004, drawing raves for its elegant, beautiful engine and brusque simplicity of gameplay.
Painkiller's Hell is a diorama of our species' capacity for self-destruction, an open-air museum in which every wicked deed, every cruelty, every occasion on which humans have displayed their ugliness is frozen in a drop of crystallized time.
Painkiller makes it clear that he's a doting husband, but despite this I always got a very sinister vibe from Danielas though he were a reformed hit man who quit the life after marriage but retains the capacity for unimaginable cruelty.
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