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Encyclopedia > Osteocyte

An osteocyte, a star-shaped cell, is the most abundant cell found in bone. Once osteoblasts become trapped in the matrix they secrete, they become osteocytes. Osteocytes are networked to each other via long processes that occupy tiny canals called canaliculi, which are used for exchange of nutrients and waste. The space that an osteocyte occupies is called a lacuna (Latin for a pit). Although osteocytes have reduced synthetic activity and, like osteoblasts are not capable of mitotic division, they are actively involved in the maintenance of bony matrix, through various mechanosensory mechanisms. Drawing of the structure of cork as it appeared under the microscope to Robert Hooke from Micrographia which is the origin of the word cell. Cells in culture, stained for keratin (red) and DNA (green). ... Grays Anatomy illustration of a human femur. ... An osteoblast (from the Greek words for bone and to build) is a mononucleate cell which produces a protein that produces osteoid. ... Canaliculi are small, microscopic canals between the various lacunae of ossified bone. ... Look up lacuna in Wiktionary, the free dictionary. ... Latin is an ancient Indo-European language originally spoken in Latium, the region immediately surrounding Rome. ...


Hydroxyapatite, calcium carbonate and calcium phosphate is deposited around the cell. Hydroxylapatite is a naturally occurring form of calcium apatite with the formula Ca5(PO4)3(OH), but is usually written Ca10(PO4)6(OH)2 to denote that the crystal unit cell comprises two molecules. ...


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Osteocyte - Wikipedia, the free encyclopedia (130 words)
An osteocyte, a star-shaped cell, is the most abundant cell found in bone.
Osteocytes are networked to each other via long processes that occupy tiny canals called canaliculi, which are used for exchange of nutrients and waste.
The space that an osteocyte occupies is called a lacuna (Latin for a pit).
Below is the complete text without illustrations (5191 words)
Osteocytes, differentiated osteoblasts regularly spaced throughout the mineralized matrix, are believed to detect bone microdamage and to transmit signals leading to its repair (17,18).
Osteocyte experiments could have been performed in cortical bone, but osteocyte apoptosis is restricted to a narrow zone of the murine femoral metaphyseal cortex (21).
Osteocytes evidently sense changes in interstitial fluid flow through canaliculi produced by mechanical forces (65), and detect changes in the levels of hormones such as estrogen and glucocorticoids that influence their survival and which circulate in the same fluid (21,66).
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