Nuclear weapons did not exist at this time, but biological weapons were being researched by Japan ( ), (see Unit 731), and chemical weapons had seen wide use.
Weapons of mass destruction, especially nuclear weapons, are rarely used because their use is essentially an "invitation" for a WMD retaliation, which in turn could escalate into a war so destructive it could easily destroy huge segments of the world's population.
Chemical and Biological Weapons: Use in Warfare, Impact on Society and Environment, by Gert G. Harigel, 2001.
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