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Encyclopedia > Nimesulide
Nimesulide structure formula
Nimesulide structure formula

Nimesulide is a prescription non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Image File history File links Nimesulide2. ... A medical prescription (â„ž) is an order (often in written form) by a qualified health care professional to a pharmacist or other therapist for a treatment to be provided to their patient. ... Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain and to achieve analgesia. ... Antipyretics are drugs that prevent or reduce fever by lowering the body temperature from a raised state. ...


It is available in a variety of forms: tablets, suppositories, water-soluble powders, and topical gels. Common disk-shaped tablets A pharmacological tablet is a medicinal or other active substance mixed with binder powders and pressed into a tablet form. ... Four 500mg acetaminophen/paracetamol suppositories A suppository is a medicine that is inserted either into the rectum (rectal suppository) or into the vagina (vaginal suppository) where it melts. ... In medicine, a topical medication is applied to body surfaces such as the skin or mucous membranes such as the vagina, nasopharynx, or the eye. ... A gel (from the lat. ...


Like most drugs in NSAID category Nimesulide is known to be Hepatotoxic (damaging to liver) in rare but unpredictable cases and should be taken with care. It did not get FDA approval in USA and is banned in a lot of countries due to cases of Jaundice and Hepatitis induced by its use. Italy was the first country to allow the drug (1985). European Medicine Evaluation Agency has banned the use of Nimesulide for children under the age of 12. Hepatotoxicity (from hepatic toxicity) is chemical-driven liver damage. ... The United States Food and Drug Administration is the government agency responsible for regulating food, dietary supplements, drugs, cosmetics, medical devices, biologics and blood products in the United States. ... Jaundice, also known as icterus (adjective:Icteric), is yellowing of the skin, sclera (the white of the eyes) and mucous membranes caused by increased levels of bilirubin in the human body. ... Hepatitis is a gastroenterological disease, featuring inflammation of the liver. ... This article is about the year. ...


Trade names

  • Ainex
  • Aulin
  • Donulide
  • Edrigyl
  • Eskaflam
  • Guaxan
  • Heugan
  • Lusemin
  • Medicox (Ecuador)
  • Mesulid
  • Nexen
  • Nimed
  • Nidol
  • Nimalox
  • Nimedex
  • Nimesil
  • Nimotas-cd
  • NIMULID
  • Plarium
  • Scaflam
  • Scaflan
  • Sulidene

External links

  • Official page
  • History and Marketing of the drug
  • A case Report on Nimesulide and its Relation with Angina

  Results from FactBites:
 
Acute generalized exanthematous pustulosis induced by nimesulide (2191 words)
Nimesulide is a new nonsteroidal anti-inflammatory (NSAID) drug with antipyretic and analgesic properties.
We report a case of acute generalized exanthematous pustulosis (AGEP) in a 50-year-old woman that was attributed to the ingestion of nimesulide.
Nimesulide should be added to the list of agents associated with this serious adverse drug reaction.
Indian Pediatrics - Editorial (1910 words)
In the nimesulide group, 30 children (63.8%) needed admission based on their clinical conditions (others were admitted only for the study) compared to 26 (52%) children in the paracetamol group.
This was a double blind randomized controlled trial to assess the efficacy of nimesulide and paracetamol in the treatment of fever in children seen at a secondary level hospital in Faridabad District of Haryana.
In conclu-sion, nimesulide has better antipyretic effect than paracetamol in children in the doses used in the study and appears to be safe for use in them.
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