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Encyclopedia > Nicomorphine

Nicomorphine (Vilan) is the 3,6-dinicotinate ester of morphine. It was developed in the early 1900s as a cough suppressant and analgesic. It is still used in some european countries for the relief of strong pain such as that caused by terminal cancer, as an alternative to diamorphine. Nicomorphine is fast acting, but relatively short lasting, with a duration of action of around 3-5 hours. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression. [1] General formula of a carboxylate ester. ... Morphine (INN) (IPA: ) is a potent opiate analgesic drug and is the principal active agent in opium. ... Heroin or diamorphine (INN) (colloquially referred to as junk, babania, horse, golden brown, smack, black tar, big H, lady H, dope, skag, juice, diesel, etc. ... An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... An itch (Latin: pruritus) is a sensation felt on an area of skin that makes a person or animal want to scratch it. ... For other uses, see Nausea (disambiguation). ... In medicine, hypoventilation exists when ventilation is inadequate to perform gas exchange. ...



CAS# 639-48-5 (Nicomorphine freebase); 35055-78-8 (Nicomorphine hydrochloride)


  1. ^ Vadon P, Rehak P. Comparison of the analgesic effect of nicomorphine in two different solutions (German). Wiener Medizinische Wochenschrift. 1979 Apr 30;129(8):217-20.


Acetorphine, Acetyldihydrocodeine, Acetylmorphone, Alfentanil, Anileridine, Bemidone, Benzylmorphine, Buprenorphine, Butorphanol, Carfentanil, Clonitazene, Codeine, Codeinone, Codeine-N-Oxide, Cyclazocine, Cyclorphan, Desomorphine, Dextropropoxyphene, Dezocine, Diacetyldihydromorphine, Diamorphine (Heroin), Diethylthiambutene, Difenoxin, Dihydrocodeine, Dihydromorphine, Dihydrocodeinone enol acetate, Dihydroetorphine, Dihydroisocodeine, Dimethylthiambutene, Diphenoxylate, Dipropanoylmorphine, Ethylketocyclazocine, Ethylmorphine, Etonitazene, Etorphine, Fentanyl, Hydrocodone, Hydromorphone, Isomethadone, Ketobemidone, Laudanum, Lefetamine, Levallorphan, Levomethorphan, Levo-alphacetylmethadol, Loperamide, Meptazinol, Metazocine, Methadone, Monoacetylmorphine, Morphine, Morphinone, Morphine-N-Oxide, Morphine-6-glucuronide, MPPP, Myorphine, Nalbuphine, Nicocodeine, Nicodicodeine, Nicomorphine, Norcodeine, Ohmefentanyl, Oxycodone, Oxymorphone, Pentazocine, PEPAP, Pethidine (Meperidine), Phenadoxone, Phenazocine, Phenoperidine, Pholcodeine, Piminodine, Racemethorphan, Remifentanil, Sufentanil, Thebaine, Thiofentanil, Tramadol An opioid is a chemical substance that has a morphine like action in the body. ... Acetyldihydrocodeine is an opiate derivative developed as a cough suppressant and analgesic. ... Acetylmorphone (Dihydromorphinone acetate) is an opiate analogue that is an acetylated derivative of hydromorphone which was developed in the early 1900s as a potential cough suppressant and analgesic. ... Alfentanil (Alfenta) is a parenteral short-acting opioid painkiller, used for anaesthesia in surgery. ... Anileridine (Leritine®) is a synthetic opioid and strong analgesic medication. ... Buprenorphine, also colloquially referred to as bupe, is an opioid drug with partial agonist and antagonist actions. ... Butorphanol (INN) is a morphinan-type synthetic opioid analgesic marketed in the US under the trade name Stadol. ... Carfentanil, also Carfentanyl, is an analogue of the popular opioid Fentanyl, and is currently the most potent opioid known [Actually Ohmefentanil is 13,000X morphine]. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl (activity in humans starting at about 1... Codeine (INN) or methylmorphine is an opiate used for its analgesic, antitussive and antidiarrheal properties. ... Codeinone is a strong Opiod. ... Dextropropoxyphene is an analgesic in the opioid category. ... Diacetyldihydromorphine (Paralaudin, Dihydroheroin) is a potent opiate derivative which is rarely used in some countries for the treatment of strong pain such as that caused by terminal cancer, as a more potent form of diamorphine. ... Heroin, also known as diamorphine (BAN) or diacetylmorphine (INN), is a semi-synthetic opioid. ... Dihydrocodeine, also called DHC and Paracodeine and by the brand names of SS Bron, Drocode, Paracodin, Codidol, Didor Continus, Dicogesic, and DF-118 amongst others, is a semi-synthetic opioid analgesic prescribed for postoperative pain, severe dyspnea, or as an antitussive. ... Dihydromorphine is a semi-synthetic opioid invented in Germany in the first years of the twentieth century. ... The chemical structure of dihydrocodeinone enol acetate Dihydrocodeinone Enol Acetate, or Thebacon, formerly marketed as its hydrochloride salt under the trade name Acedicon, is a semisynthetic opioid once used as an antitussive, primarily in Europe. ... On opiod agonist used for the treatment of diarrhea. ... Dipropanoylmorphine is the 3,6-dipropanoyl ester of morphine. ... Ethylmorphine is a drug in the class of both opiates (representing a minor synthetic change from morphine) and opioids (being effective in the CNSs opioid reception system) . Its effects in humans mainly stem from its metabolic conversion to morphine. ... Etonitazene, (2-(p-Ethoxybenzyl)-1-diethylaminoethyl-5-nitrobenzimidazole), is a schedule I opiate. ... Etorphine (Immobilon® or M99) is a synthetic cousin of morphine and 1000 - 80,000 times more powerful. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... It has been suggested that Vicodin be merged into this article or section. ... Hydromorphone is a drug used to relieve moderate to severe pain. ... Ketobemidone structure Ketobemidone is a powerful opioid analgesic. ... Laudanum is an opium tincture, sometimes sweetened with sugar and also called wine of opium. ... Lefetamine is a psychoactive drug which has effects similar to both morphine and methylphenidate. ... Levomethorphan is an optical isomer of dextromethorphan. ... Levo-alpha-acetyl-methadol (LAAM for short) is a synthetic opioid similar in structure to methadone. ... Loperamide, usually as hydrochloride, is a drug effective against diarrhea resulting from gastroenteritis or inflammatory bowel disease. ... Methadone is a synthetic opioid, used medically as an analgesic and in the treatment of narcotic addiction. ... 6-monoacetylmorphine (6-MAM) is one of 2 active metabolites of heroin (diacetylmorphine), the other being the much less active 3-monoacetylmorphine (3-MAM). ... Morphine (INN) (IPA: ) is a potent opiate analgesic drug and is the principal active agent in opium. ... Morphinone is a very strong Opiod. ... Morphine-6-glucuronide (M6G) is of more than simply academic interest, since it is the major active metabolite of morphine, and as such is the molecule responsible for much of the pain-relieving effects of morphine (and heroin and codeine). ... MPPP (1-methyl 4-phenyl 4-propionoxypiperidine) is an opioid analgesic drug. ... Nalbuphine (nalbuphine hydrochloride) is a synthetic opioid used commercially as an analgesic under a variety of trade names, including Nubain. ... Nicocodeine (Lyopect) is an opiate derivative developed as a cough suppressant and analgesic. ... Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. ... // Ohmefentanyl (OMF) is related to a fentanyl analogue called 3-methyl-fentanyl (3-MF)[1],[2]. OMF is more sophisticated than 3-MF though since it also has a β-hydroxy group situated on the phenethyl tail. ... Not to be confused with oxytocin. ... Oxymorphone (Numorphan) is a powerful semi-synthetic narcotic analgesic that is derived from morphine, and is approximately 6-8 times more potent. ... Pentazocine is a synthetically-prepared narcotic drug used to treat mild to moderate pain. ... Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; operidine; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ... Phenoperidine is an opiod general anesthetic. ... Racemethorphan is a racemic mixture of the stereoisomers of methorphan , namely dextromethorphan , which is the active ingredient in DM cough syrups , and the lesser known levomethorphan which is described as a controlled substance in The Merck Index - likely because it has more potential for abuse than its dextro enantiomer . ... Remifentanil is a potent ultra short-acting synthetic opioid analgesic drug. ... Sufentanil is a drug that belongs to the class of drugs known as the opioid analgesic drugs. ... A minor constituent of opium, thebaine or paramorphine (C19H21NO3) is chemically similar to both morphine and codeine, but produces stimulatory rather than depressant effects. ... Tramadol (INN) (IPA: ) is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. ...

  Results from FactBites:
Dihydromorphine at AllExperts (368 words)
It is most often seen these days as an intermediate in the manufacture of dihydrocodeine as well as in some methods of manufacture of hydrocodone, hydromorphone, and related drugs.
Known as Paramorfan, it was never introduced in the United States as was the case of many similar drugs invented in Europe in the two decades prior to the First World War such as thebacon, nicomorphine (Vilan), benzylmorphine (Peronine) and others.
For this reason, it shares a Schedule I designation under the Controlled Substances Act of 1970 with these other opioids in the United States.
Method and a pharmaceutical preparation for treating pain - Patent 5187177 (1438 words)
Furthermore, the use of glucagon for the preparation of a pharmaceutical preparation for treating pain is disclosed.
A method as claimed in claim 1 wherein the spasmogenic analgesic is a narcotic opiate-like substance selected from the group consisting of morphine, nicomorphine, fentanyl, mepiridine, alfentanile, pethidine, ketobemidon, dextromoramide, and methadone.
In practice of the method of the invention, glucagon and the analgesic may be administered in manners conventional for giving the analgesic treatment, e.g., in the form of subcutaneous injection separate preparations.
  More results at FactBites »



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