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Encyclopedia > Neurospora crassa
How to read a taxoboxNeurospora crassa

Scientific classification
Kingdom: Fungi
Phylum: Ascomycota
Class: Ascomycetes
Order: Sordariales
Family: Sordariaceae
Genus: Neurospora
Species: N. crassa
Binomial name
Neurospora crassa
Shear & B.O. Dodge

Neurospora crassa is a type of red bread mold of the phylum Ascomycota. The genus name, meaning "nerve spore" refers to the characteristic striations on the spores that resemble axons. This article explains how to read a taxobox. ... Image File history File links Neurospora_big. ... For other uses, see Scientific classification (disambiguation). ... Divisions Chytridiomycota Zygomycota Glomeromycota Ascomycota Basidiomycota Deuteromycota For the fictional character, see Fungus the Bogeyman. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... Classes Archaeascomycetes Hemiascomycetes Euascomycetes Neolectomycetes Pezizomycotina Pneumocystidomycetes Saccharomycotina Schizosaccharomycetes Taphrinomycetes mitosporic Ascomycota Members of the Division Ascomycota are known as the Sac Fungi and are fungi that produce spores in a distinctive type of microscopic sporangium called an ascus (Greek for a bag or wineskin). This monophyletic grouping was formerly... Sordariales are an order of fungi within the class Sordariomycetes (also known as Pyrenomycetes), subphylum Pezizomycotina, phylum Ascomycota. ... Genus Sordaria Neurospora Gelasinospora Monilla Sordariaceae is a family of fungi within the order sordariales. ... Species N. crassa N. intermedia N. sitophila N. tetrasperma Neurospora is a genus of fungi. ... In biology, binomial nomenclature is the formal method of naming species. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... This article is about a biological reproductive structure; for the video game, see Spore (video game). ... An axon or nerve fiber, is a long, slender projection of a nerve cell, or neuron, that conducts electrical impulses away from the neurons cell body or soma. ...

N. crassa is notable for its use as a model organism in science because it is easy to grow and has a haploid life cycle that makes genetic analysis simple since recessive traits will show up in the offspring. Its entire genome of seven chromosomes has been sequenced [1]. Neurospora was used by Edward Tatum and George Wells Beadle in their experiments for which they won the Nobel Prize in Physiology or Medicine. Beadle and Tatum exposed N. crassa to x-rays, causing mutations. They then observed failures in metabolic pathways caused by errors in specific enzymes. This led to the "one gene, one enzyme" hypothesis that states that specific genes code for specific proteins. A model organism is a species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into the workings of other organisms. ... Part of a scientific laboratory at the University of Cologne. ... Haploid (meaning simple in Greek) cells have only one copy of each chromosome. ... For a non-technical introduction to the topic, please see Introduction to genetics. ... In biology the genome of an organism is the whole hereditary information of an organism that is encoded in the DNA (or, for some viruses, RNA). ... Tatum won the Nobel Prize for his work in genetics Edward Lawrie Tatum (December 14, 1909 - November 5, 1975) was an American geneticist. ... Beadle won a Nobel Prize in 1958 George Wells Beadle (October 22, 1903 – June 9, 1989) was an American scientist in the field of genetics. ... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ... This article is about mutation in biology, for other meanings see: mutation (disambiguation). ... In biochemistry, a metabolic pathway is a series of chemical reactions occurring within a cell, catalyzed by enzymes, resulting in either the formation of a metabolic product to be used or stored by the cell, or the initiation of another metabolic pathway (then called a flux generating step). ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... This stylistic schematic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). ... A representation of the 3D structure of myoglobin, showing coloured alpha helices. ...

In the 24 April 2003 issue of Nature, the genome of N. crassa was reported as completely sequenced. The genome is about 43 megabases long and includes approximately 10,000 genes. Currently there is a project underway to produce mutant knockouts for every gene in the genome of N. crassa. These mutants are provided at an extremely low price in return for any research information gathered on them. First title page, November 4, 1869 Nature is one of the oldest and most reputable scientific journals, first published on 4 November 1869. ... In biology the genome of an organism is the whole hereditary information of an organism that is encoded in the DNA (or, for some viruses, RNA). ... DNA sequencing is the process of determining the nucleotide order of a given DNA fragment, called the DNA sequence. ...

In its natural environment, N. crassa lives mainly in tropical and sub-tropical regions. It can be found growing on dead plant matter after fires.


  • Perkins, D & Davis, R (Dec, 2000), "Evidence for Safety of Neurospora Species for Academic and Commercial Uses", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 66 (12):5107-5109. PMID 11097875
  • Osherov, N & May, GS (May 30, 2001), "The molecular mechanisms of conidial germination", FEMS Microbiol Lett, vol. 199(2):153-60. PMID 11377860
  • Froehlich, AC, Noh, B & Vierstra, RD, Loros J & Dunlap JC (December 2005), "Genetic and molecular analysis of Phytochromes from the filamentous fungus Neurospora crassa", Eukaryot Cell, vol. 4(12):2140-52. PMID 16339731
  • Horowitz, NH (April 1991), "Fifty years ago: the Neurospora revolution", Genetics. PMID 1827628
  • Horowitz, NH, Berg, P & Singer, M, Lederberg J, Susman M, Doebley J & Crow JF. (January 2004), "A centennial: George W. Beadle, 1903-1989", Genetics, vol. 166(1):1-10. PMID 15020400
  • Kaldi, K, Gonzalez, BH & Brunner, M (December 23, 2005), "Transcriptional regulation of the Neurospora circadian clock gene wc-1 affects the phase of circadian output", EMBO Rep. PMID 16374510
  • Pittalwala, Iqbal (April 29, 2003), "UC Riverside scientists contribute to study that unveils genome sequence of bread mold", Newsroom (University of California, Riverside).
  • Ruoff, P, Loros, JJ & Dunlap, JC (December 6, 2005), "The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock", Proc Natl Acad Sci USA. PMID 16314576
  1. ^ Trans-NIH Neurospora Initiative

DEC, dec or Dec may refer to: December - a month of the year in the Gregorian Calendar Department of Environment and Conservation Digital Equipment Corporation - a computer and technology company, now part of HP Declination - a term from astronomy Diethylcarbamazine - a drug commonly used to treat infections by filarial parasites... This article is about the year 2000. ... May 30 is the 150th day of the year in the Gregorian calendar (151st in leap years). ... 2001 (MMI) was a common year starting on Monday of the Gregorian calendar. ... December 23 is the 357th day of the year in the Gregorian Calendar (358th in leap years). ... 2005 (MMV) was a common year starting on Saturday of the Gregorian calendar. ... April 29 is the 119th day of the year in the Gregorian calendar (120th in leap years). ... 2003 (MMIII) was a common year starting on Wednesday of the Gregorian calendar. ... December 6 is the 340th day (341st on leap years) of the year in the Gregorian calendar. ... 2005 (MMV) was a common year starting on Saturday of the Gregorian calendar. ...

External links

Major Model Organisms in Genetic Studies
Lambda phage | E. coli | Chlamydomonas | Tetrahymena | Budding yeast | Fission yeast | Neurospora | Maize | Arabidopsis | C. elegans | Drosophila | Zebrafish | Rat | Mouse

  Results from FactBites:
Metal transportome of Neurospora crassa (3893 words)
Neurospora crassa has been the model filamentous fungus for the study of many fundamental cellular mechanisms of transport and metabolism.
Neurospora crassa is a multicellular filamentous fungus playing central role as model organism in the history of twentieth century genetics, biochemistry and molecular biology.
Knockout mutants of Neurospora crassa would be useful in characterization of metal ion transporters and the recent Neurospora genome project initiative directed towards the above is in active progress (http://www.dartmouth.edu/~neurosporagenome/1_s1.html).
  More results at FactBites »



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