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Encyclopedia > NeuGene

NeuGene is a trademark describing Morpholino antisense oligos in development as pharmaceuticals by AVI BioPharma, Inc. www.avibio.com. The "Neu" in the name refers to the uncharged (neutral) nature of the Morpholino oligo. Publications by AVI scientists and collaborators often refer to Morpholino oligos as PMO, an acronym for phosphorodiamidate morpholino oligo. Morpholino oligos are an antisense nucleic acid technology used to block access of other molecules to specific sequences within mRNA molecules. ... See British Prime Ministers Office Canadian Prime Ministers Office Icelandic Prime Ministers Office Serbian Prime Ministers Office This is a disambiguation page — a navigational aid which lists other pages that might otherwise share the same title. ...


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AVI BioPharma - NeuGene Antisense (559 words)
NeuGene antisense technology is based on synthetic subunits, as opposed to modified natural materials.
In addition, in NeuGene technology, the linkages used to string the subunits together are uncharged molecules.
Because the NeuGene backbone is a unique synthetic structure, there are no enzymes found in humans to degrade it.
Pharmacy Choice - Pharmaceutical News - U.S. IND submitted for Neugene antisense drug targeting hepatitis C virus - ... (623 words)
Another Neugene drug, AVI-4020, is currently being studied in a clinical trial of patients exhibiting presumptive neuroinvasive disease caused by West Nile virus.
In addition, Neugene drugs are being tested against a variety of hemorrhagic, infectious and toxin-producing agents in collaboration with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), the Walter Reed Army Institute of Research (WRAIR), and the Centers for Disease Control and Prevention (CDC).
Hepatitis C infection is an inflammation of the liver caused by the hepatitis C virus.
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