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Encyclopedia > Myotome

In vertebrate embryonic development, a group of tissues formed from somites that develop into the body wall muscle. In the developing vertebrate embryo, somites are masses of mesoderm distributed along the two sides of the neural tube and that will eventually become dermis, skeletal muscle and vertebrae. ...


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Myotome meanderings. Cellular morphogenesis and the making of muscle (4596 words)
Myotome precursor cells are known to translocate from the dermomyotome to form the underlying myotome layer.
Some pioneering studies suggested that the cells of the early myotome all originate from one specific position within the dermomyotome, the dorsal medial lip (DML), which is the most axial region of the dermomyotome and is juxtaposed to the dorsal aspect of the neural tube (Williams, 1910; Hamilton, 1952; Boyd, 1960).
This mechanism of myotomal growth resembles the amniote model of myotome formation described by Ordahl and colleagues (2001), in which both the dorsomedial and ventrolateral lips of the chick dermomyotome contribute to myotome formation.
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