The myometrium is the middle layer of the uterine wall consisting of smooth muscle cells and supporting stromal and vascular tissue. The inner layer of the uterine wall is the endometrium or uterine lining, and the outer layer the serosa or peritoneum. The myometrium stretches (the smooth muscle cells expand in size, rather than number) during pregnancy to allow for the harboring of the pregnancy, and contracts in a coordinated fashion during the process of labor. After delivery the myometrium contracts to expell the placenta and reduce blood loss. Lack of contraction at this stage is termed uterine atony. After pregnancy the uterus returns to its nonpregnant size by a process of myometrial involution. Female internal reproductive anatomy The uterus or womb is the major female reproductive organ of most mammals, including humans. ... The endometrium is the uterine membrane in mammals which is thickened in preparation for the implantation, of a fertilized egg upon its arrival into the uterus. ... In higher vertebrates, the peritoneum is the membrane that forms the lining of the abdominal cavity - it covers most of the intra-abdominal organs. ... A pregnant woman Pregnancy is the carrying of one or more embryos or feti by female mammals including humans inside their bodies. ... Childbirth in a hospital. ... Human placenta shown a few minutes after birth. ...
Neoplasms of the myometrium are very common, termed uterine leiomyomata or fibroids. Their malignant version, leiomyosarcoma, is rare. A leiomyoma (plural is leiomyomata) is a benign smooth muscle neoplasm that is not premalignant. ...
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