FACTOID # 6: Michigan is ranked 22nd in land area, but since 41.27% of the state is composed of water, it jumps to 11th place in total area.
 
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Encyclopedia > Multipotent

Multipotent stem cells can give rise to several other cell types, but those types are limited in number. An example of multipotent cells is hematopoietic cells—blood stem cells that can develop into several types of blood cells but cannot develop into brain cells. At the end of the long chain of cell divisions that make up the embryo are terminally differentiated cells—cells that are considered to be permanently committed to a specific function.



Scientists have long held the opinion that differentiated cells cannot be altered or caused to behave in any way other than the way in which they have been naturally committed. New research, however, has even called that assumption into question. In recent stem cell experiments, scientists have been able to persuade blood stem cells to behave like neurons, or brain cells. Scientists now believe that stem cell research could reveal far more vital information about our bodies than was previously known. There is also continuing research to see if it is possible to make multipotent cells into pluripotent drugs.


  Results from FactBites:
 
Multipotency - Wikipedia, the free encyclopedia (217 words)
Multipotent progenitor cells can give rise to several other cell types, but those types are limited in number.
An example of a multipotent stem cell is a hematopoietic cell — a blood stem cell that can develop into several types of blood cells, but cannot develop into brain cells or other types of cells.
At the end of the long series of cell divisions that form the embryo are cells that are terminally differentiated, or that are considered to be permanently committed to a specific function.
Stem cells: Harnessing stem cell potential - Cell Signaling Update - Signaling Gateway (454 words)
To exploit the full potential of neural stem cells, it is essential to identify not only the factors that promote their differentiation, but also the factors that preserve the stem-cell state.
However, Sox10 also acts as a brake to delay or prevent the terminal differentiation of neurons, an activity that is reflected in its ability to repress Phox2a, a close relative of Phox2b.
Multipotent cell lineages in early mouse development depend on SOX2 function.
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