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Encyclopedia > Meloxicam

Molecular structure of meloxicam
Meloxicam Structure of meloxicam File links The following pages link to this file: Meloxicam Categories: User-created public domain images ...

"4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide"

Metabolism no known metabolites
Half life 20 hours
Recommended dosage 7.5 mg qd
Excretion unknown
Pregnancy category unknown

Meloxicam is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. It is closely related to piroxicam. Main article: Exponential decay The half-life of a quantity subject to exponential decay is the time required for the quantity to fall to half of its initial value. ... Excretion is the biological process by which an organism chemically separates waste products from its body. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother. ... Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Arthritis (from Greek arthro-, joint + -itis, inflammation) is a group of conditions that affect the health of the bone joints in the body. ... Dysmenorrhea (or dysmenorrhoea), cramps or painful menstruation, involves menstrual periods that are accompanied by either sharp, intermittent pain or dull, aching pain, usually in the pelvis or lower abdomen. ... Fever is also the name of an album by Kylie Minogue. ... An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain and to achieve analgesia. ... Inflammation is the first response of the immune system to infection or irritation and may be referred to as the innate cascade. ... Piroxicam (US trade name Feldene) is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ...


In Europe it is marketed under the names of Movalis, Melox, and Recoxa.


Mechanism of action

Meloxicam is an NSAID, and as such is a cyclooxygenase (COX) inhibitor. It is generally marketed under the name MOBIC. Meloxicam has been shown, especially at its low therapeutic dose, to selectively inhibit COX-2 over COX-1. Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Cyclooxygenase (COX) is an enzyme (EC 1. ...


Main article: Non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ...


Adverse effects

Meloxicam use can result in gastrointestinal toxicity, tinnitus, headache, and rash. The risk of adverse side effects is lower than with piroxicam, diclofenac, or naproxen. Although it does inhibit thromboxane A, it does not appear to do so at levels that would interfere with platelet function. Piroxicam (US trade name Feldene) is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ... Diclofenac (marketed as Voltaren®, Voltarol®, Diclon® and Cataflam®) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation, such as in arthritis or acute injury. ... Naproxen (trade names: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the... Thromboxane is a member of the family of lipids known as eicosanoids. ... A 250 ml bag of newly collected platelets. ...


Approval status

Meloxicam is quite popular in Europe for treatment of rheumatoid arthritis. It has recently (as of 2004) been approved for use in treating osteoarthritis in the United States. Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. ... Osteoarthritis (OA, also known as degenerative arthritis or degenerative joint disease, and sometimes referred to as arthrosis or osteoarthrosis), is a condition in which low-grade inflammation results in pain in the joints, caused by wearing of the cartilage that covers and acts as a cushion inside joints. ...



Analgesics edit

Paracetamol (acetaminophen) | NSAIDs | Opiates | Tetrahydrocannabinol An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain and to achieve analgesia. ... Paracetamol (INN) (IPA: ) or acetaminophen (USAN) is a common analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Wikipedia does not yet have an article with this exact name. ... An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... Tetrahydrocannabinol, also known as THC, Δ9-THC, Δ9-tetrahydrocannabinol (delta-9-tetrahydrocannabinol), Δ¹-tetrahydrocannabinol (using an older numbering scheme), or dronabinol, is the main psychoactive substance found in the Cannabis plant. ...

NSAIDs edit

Aspirin | Celecoxib | Diclofenac | Diflunisal | Flurbiprofen | Ibuprofen | Indomethacin | Ketoprofen | Ketorolac | Mefenamic acid | Meloxicam | Naproxen | Piroxicam | Rofecoxib | Valdecoxib | Sulindac Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Aspirin or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum growths polyps in patients with familial adenomatous polyposis. ... Diclofenac (marketed as Voltaren®, Voltarol®, Diclon® and Cataflam®) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation, such as in arthritis or acute injury. ... Diflunisal is a generic NSAID (Non Steroidal Anti Inflammatory Drug). ... Flurbiprofen is an NSAID (non-steroidal anti-inflammatory drug) used to treat the inflammation and pain of arthritis. ... Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely marketed under various trademarks including Act-3, Advil, Brufen, Motrin, Nuprin, and Nurofen. ... Indomethacin (USAN) or indometacin (INN) is a non-steroidal anti-inflammatory drug commonly used to reduce fever, pain, stiffness, and swelling. ... Ketoprofen, (RS)2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. ... Ketorolac or ketorolac tromethamine (marketed as Toradol® - generics have been approved) is a non-steroidal anti-inflammatory drug (NSAID) in the family of propionic acids, often used as an analgesic, antipyretic (fever reducer), and anti-inflammatory. ... This article needs to be cleaned up to conform to a higher standard of quality. ... Naproxen (trade names: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the... Piroxicam (US trade name Feldene) is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ... Rofecoxib (IPA: ) is a nonsteroidal anti-inflammatory drug (NSAID) that was used in the treatment of osteoarthritis, acute pain conditions, and dysmenorrhoea. ... Valdecoxib is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. ... Sulindac is a non-steroidal anti-inflammatory drug of the arylalkanoic acid class that is marketed in the U.S. as Clinoril. ...

Opioids edit

Alfentanil | Buprenorphine | Butorphanol | Carfentanil | Codeine | Codeinone | Dextropropoxyphene | Diamorphine (Heroin) | Dihydrocodeine | Fentanyl | Hydrocodone | Hydromorphone | Methadone | Morphine | Morphinone | Nalbuphine | Oxycodone | Oxymorphone | Pentazocine | Pethidine (Meperidine) | Propoxyphene | Remifentanil | Sufentanil | Tramadol An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... Alfentanil (Alfenta) is a parenteral short-acting opioid painkiller, used for anaesthesia in surgery. ... Buprenorphine, also colloquially referred to as bupe, is an opioid drug with partial agonist and antagonist actions. ... Butorphanol (INN) is a morphinan-type synthetic opioid analgesic marketed in the US under the trade name Stadol. ... Carfentanil, also Carfentanyl, is an analogue of the popular opioid Fentanyl, and is currently the most potent opioid known [Actually Ohmefentanil is 13,000X morphine]. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl (activity in humans starting at about 1... Codeine (INN) or methylmorphine is an opioid used for its analgesic, antitussive and antidiarrheal properties. ... Codeinone is a strong Opiod. ... Dextropropoxyphene is an analgesic in the opioid category. ... Heroin or diacetylmorphine (INN) is a semi-synthetic opioid. ... Dihydrocodeine, also called DHC or DF-118, is a synthetic opioid analgesic prescribed for postoperative pain, severe dyspnea, or as an antitussive. ... Fentanyl is an opioid analgesic, first synthesized in Belgium in the late 1950s, with an analgesic potency of about 80 times that of morphine. ... Hydrocodone or dihydrocodeinone (marketed as Vicodin, Anexsia, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Hydroco, Tussionex, Vicoprofen) is an opioid derived from either of the naturally occurring opiates codeine or thebaine. ... // Overview Hydromorphone is a drug used to relieve moderate to severe pain. ... Methadone is a synthetic opioid, used medically as an analgesic and in the treatment of narcotic addiction. ... Morphine (INN), the principal active agent in opium, is a powerful opioid analgesic drug. ... Morphinone is a very strong Opiod. ... Nalbuphine (nalbuphine hydrochloride) is a synthetic opioid used commercially as an analgesic under a variety of trade names, including Nubain. ... Oxycodone is a very powerful and potentially addictive opioid analgesic medication synthesized from thebaine. ... Oxymorphone (Numorphan) is a powerful semi-synthetic narcotic analgesic that is derived from morphine, and is approximately 6-8 times more potent. ... Pentazocine is a synthetically-prepared narcotic drug used to treat mild to moderate pain. ... Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; operidine; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ... Dextropropoxyphene is an analgesic in the opioid category that is used to treat severe pain and severe coughs. ... Remifentanil is a potent ultra short-acting synthetic opioid analgesic drug. ... Sufentanil is a drug that belongs to the class of drugs known as the opioid analgesic drugs. ... Tramadol (INN) (IPA: ) is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. ...


  Results from FactBites:
 
Meloxicam - Wikipedia, the free encyclopedia (186 words)
Meloxicam is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component.
Meloxicam is an NSAID, and as such is a cyclooxygenase (COX) inhibitor.
Meloxicam is quite popular in Europe for treatment of rheumatoid arthritis.
meloxicam Information on Healthline (687 words)
celecoxib naproxen valdecoxib indomethacin ibuprofen and pseudoephedrine diclofenac ketoprofen ketorolac piroxicam flurbiprofen sulindac meloxicam etodolac nabumetone oxaprozin magnesium salicylate tolmetin fenoprofen
Meloxicam is used to reduce the pain, inflammation, and stiffness caused by osteoarthritis and rheumatoid arthritis..
Meloxicam should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart.
  More results at FactBites »

 
 

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