FACTOID # 21: 15% of Army recruits from South Dakota are Native American, which is roughly the same percentage for female Army recruits in the state.
 
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Encyclopedia > Malignant

In medicine, malignant is a clinical term that means to be severe and become progressively worse, as in malignant hypertension. In the context of cancer, a malignant tumor can invade and destroy nearby tissue and may also spread (metastasize) to other parts of the body. medicines, see medication and pharmacology. ... For other forms of hypertension, see Hypertension (disambiguation). ... Cancer is a class of diseases or disorders characterized by uncontrolled division of cells and the ability of these to spread, either by direct growth into adjacent tissue through invasion, or by implantation into distant sites by metastasis (where cancer cells are transported through the bloodstream or lymphatic system). ... Tumor or tumour literally means swelling, and is sometimes still used with that meaning. ... Metastasis (Greek: change of the state) is the spread of cancer from its primary site to other places in the body. ...


The word malignant comes the Latin combination of "mal" meaning "bad" and "nascor" meaning "to be born"; malignant literally means "born to be bad." Strictly speaking, a malignant tumor is one that possesses the ability to invade adjacent tissues and spread distantly. Just because a tumor is diagnosed as malignant by a pathologist does not mean that the patient will progress rapidly to death. More and more, patients with malignant tumors are living for many years after diagnosis and treatment. The actual prognosis depends of the type of tumor, its differentiation, and the stage (extent) of disease. The term malignant is typically applied to neoplasms that show aggressive behavior characterised by local invasion or distant metastasis. Prognosis (older Greek πρόγνωσις, modern Greek πρόγνωση - literally fore-knowing, foreseeing) is a medical term denoting the doctors prediction of how a patients disease will progress, and whether there is chance of recovery. ... Neoplasia (literally: new growth) is sudden and abnormal growth in a tissue or organ. ... Metastasis (Greek: change of the state) is the spread of cancer from its primary site to other places in the body. ...


The change of cells from benign to malignant behavior is called malignant transformation. This diagnosis is made by pathologic examination of tissues. Often the clincial signs and symptoms are suggestive of a malignant tumor. The physician, during the medical history examination, can find that there have been changes in size or patient sensation and, upon direct examination, that there has been a change in the lesion itself. Benign can refer to any medical condition which, untreated or with symptomatic therapy, will not become life-threatening. ... Pathology (from Greek pathos, feeling, pain, suffering; and logos, study of; see also -ology) is the study of the processes underlying disease and other forms of illness, harmful abnormality, or dysfunction. ... The medical history of a patient (sometimes called anamnesis [1][2] ) is information gained by a physician by asking specific questions, either of the patient or of other people who know the person and can give suitable information (in this case, it is sometimes called heteroanamnesis). ... A lesion is a non-specific term referring to abnormal tissue in the body. ...


Malignant transformation is a synonym for progression to malignancy. Transformation may take place as a primary or a secondary process.


There are many causes of malignant transformation. The underlying commonality is genetic mutation either by inheritance or more commonly by acquiring mutations in one's DNA over time. Although malignant transformation may occur because of changes within the cell, it can be induced by inorganic toxic substances such as cadmium or arsenite and organics such as tobacco-specific nitrosamines. It is also thought that some malignant transformations are due to viruses such as the Epstein-Barr virus, although this is currently restricted to just a few cancer types. A more common cancer associated with viral infection is cervical cancer, which has been linked to the human papilloma virus. The structure of part of a DNA double helix Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions for the development and function of living organisms. ... Toxic redirects here, but this is also the name of a song by Britney Spears; see Toxic (song) Look up toxic and toxicity in Wiktionary, the free dictionary. ... General Name, Symbol, Number cadmium, Cd, 48 Chemical series transition metals Group, Period, Block 12, 5, d Appearance silvery gray metallic Atomic mass 112. ... The arsenite ion is H2AsO3−, or similar. ... Nitrosamines are carcinogenous chemical compounds of the chemical structure R2N-N=O. Nitrosamines are produced from nitrites and amines. ... The Epstein-Barr virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalovirus), and one of the most common viruses in humans. ... Cervical cancer is a malignancy of the cervix. ... Human papillomavirus (HPV) is a virus which affects humans. ...


Malignant qualities in cancer may be due to still multiplying cells, or cells that break off from the main tumour and enter the blood stream, being transported elsewhere where the cells that broke off are able to reproduce further, thus spreading the cancer.


Risk assessments can be done and are known for certain populations. One of the better known of these progression and risks is the progression of a nevus to melanoma. Risk assessment is a step in the risk management process. ... Nevus (or naevus) is a general term that refers to a number of different, usually benign, pigmented lesions of the skin. ... Melanoma is a malignant tumor of melanocytes. ...


  Results from FactBites:
 
Malignant - Wikipedia, the free encyclopedia (226 words)
In medicine, malignant is a clinical term that is used to describe a clinical course that progresses rapidly to death.
Malignant transformation is a synonym for progression to malignancy.
Although malignant transformation may occur because of changes within the cell, it can be induced by inorganic toxic substances such as cadmium or arsenite and organics such as tobacco-specific nitrosamines.
s000522e - Myositis and Malignancy (2840 words)
Dermatomyositis and polymyositis: preceded the ovarian malignancy in nine patients, were concomitant with it in four, and succeeded the ovarian disease in: one.
The frequencies of malignant: neoplasms occurring prior to or concurrent with initial RDU admission were compared, using case-control methods, with: age- and sex-matched control groups with a diagnosis of any non-PM/DM rheumatic disease (rheumatic disease: controls) or osteoarthritis, fibrositis, or fracture (noninflammatory musculoskeletal controls).
In a cohort analysis, the: incidence of malignant neoplasm subsequent to initial RDU admission in patients with PM/DM was compared with the: expected incidence in the Canadian population.
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