The macule is the simplest dermatological lesion. It is flat and can only be seen and not felt. The macule is noted by a change in color of the skin. It may be brown, blue, red or exhibit a lesser pigment or an absence of pigment. The color of the lesion is one way in which a diagnosis may be focused.
Acquired bilateral nevus of Ota-like macules were first described in 1984 as blue-brown or slate-gray, small patches that occurred on the lateral sites of the forehead, temples, upper eyelids, malar areas, root of the nose, and ala nasi, without ocular or mucosal pigmentation .
The macules are most often seen in women of Asian descent and usually appear in the fourth or fifth decade .
Acquired bilateral nevus of Ota-like macules are differentiated from bilateral nevus of Ota by the later age of onset and the lack of conjunctival, mucosal, and tympanic membrane involvement .
Numerous tan-to-medium-brown macules and patches that measured 2 mm to 6 cm in diameter were present on the face, trunk, and extremities, with an increased density of smaller macules in the axillae and groin.
Although blue-red macules are characterized by their color and pseudoatrophic macules by their anetoderma-like appearance, there is considerable overlap between the two entities.
Blue-red macules have been observed in patients as young as five years of age, and pseudoatrophic macules may be present at birth.
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