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Encyclopedia > John Lykoudis

John Lykoudis (born 1910 in Missolonghi, died 1980) was a general practitioner in Greece who treated patients from peptic ulcer disease with antibiotics long before it was commonly recognized that bacteria were a dominant cause for the disease. 1910 (MCMX) was a common year starting on Saturday (see link for calendar) of the Gregorian calendar or a common year starting on Sunday of the 13-day slower Julian calendar. ... Messolonghi, also Messolongi, Mesolongi (Greek, Modern: Μεσολόγγι, Ancient/Katharevousa: -on), older forms Messolongio, Mesolongio, Messolongion, Messolonghion is a town of about 12,000 people (as of 1991 census) in central Greece. ... 1980 (MCMLXXX) was a leap year starting on Tuesday. ... A general practitioner (GP) or family physician (FP) is a physician/medical doctor who provides primary care. ... Peptic ulcer is a non-malignant ulcer of the stomach (called gastric ulcer) or duodenum (called duodenal ulcer). ... An antibiotic is a drug that kills or slows the growth of bacteria. ... Phyla/Divisions Actinobacteria Aquificae Bacteroidetes/Chlorobi Chlamydiae/Verrucomicrobia Chloroflexi Chrysiogenetes Cyanobacteria Deferribacteres Deinococcus-Thermus Dictyoglomi Fibrobacteres/Acidobacteria Firmicutes Fusobacteria Gemmatimonadetes Nitrospirae Omnibacteria Planctomycetes Proteobacteria Spirochaetes Thermodesulfobacteria Thermomicrobia Thermotogae Bacteria (singular, bacterium) are a major group of living organisms. ...


After treating himself for peptic ulcer disease with antibiotics in 1958 and finding the treatment effective he began treating patients with antibiotics. After experimenting with several combinations of antibiotics he eventually arrived at a combination which he termed Elgaco and which he patented in 1961. It has been estimated that he treated more than 30,000 patients. 1958 (MCMLVIII) was a common year starting on Wednesday of the Gregorian calendar. ... 1961 (MCMLXI) was a common year starting on Sunday (the link is to a full 1961 calendar). ...


In his time he had great difficulties in persuading the Greek medical establishment about the effectiveness of the treatment. He was given a fine of 4000 drachmas by a disciplinary committee, and indicted in the Greek courts. He was unable to get an article published in the Journal of the American Medical Association and was not able to get the established phamaceutical companies sufficiently interested in the treatment. Drachma, pl. ... JAMA, published continuously since in 1883, is an international peer-reviewed general medical journal published 48 times per year. ...


John Lykoudis was the mayor of Missolonghi between 1952 and 1960. Messolonghi, also Messolongi, Mesolongi (Greek, Modern: Μεσολόγγι, Ancient/Katharevousa: -on), older forms Messolongio, Mesolongio, Messolongion, Messolonghion is a town of about 12,000 people (as of 1991 census) in central Greece. ... 1952 (MCMLII) was a Leap year starting on Tuesday (link will take you to calendar). ... 1960 (MCMLX) was a leap year starting on Friday (the link is to a full 1960 calendar). ...


See also

Reference

  • Basil Rigas, Efstathios D. Papavasassiliou, "John Lykoudis. The general parctitioner in Greece who in 1958 discovered the etiology of, and a treatment for, peptic ulcer disease", in Barry Marshall (editor), Helicobacter Pioneers. Firsthand accounts from the scientists who discovered helicobacters, 1892-1982, 2002, ISBN 0-86793-035-7.

  Results from FactBites:
 
Science Show - 15/2/2003: The Helicobacter Story (6348 words)
One is that we have the written testimony of scores of patients because Lykoudis was towards the end of his career with Elgaco, he was persecuted, and we have actually sworn testimony by several patients who said that his medication did work.
John Glidden: I was a little bit sceptical at the start but when he spoke to us about it and said he’d actually swallowed a mixture of the bacterium and was extremely sick himself I started to believe him.
John Glidden: We now treat the patients obviously with anti helicobacter therapy which is a one to two week course of antibiotics and proton pump inhibiters.
Review Article (4976 words)
Treatment of peptic ulcers specifically with antibiotics was first proposed by John Lykoudis.
Although Lykoudis presented his ideas to the drug companies and attempted publication in refereed journals, the concept of a bacterial cause of peptic ulcer was ignored and none of his work was ever published.
John Lykoudis: an unappreciated discoverer of the cause and treatment of peptic ulcer disease.
  More results at FactBites »

 
 

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