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Encyclopedia > James D. Watson
James Dewey Watson
James D. Watson
James D. Watson
Born April 6, 1928 (1928-04-06) (age 80)
Chicago, Illinois, U.S.
Residence U.S., UK
Nationality American
Fields molecular biologist
Doctoral advisor Salvador Luria
Known for DNA structure, Molecular biology
Notable awards Nobel Prize (1962)
Religious stance Atheist[1][2]

James Dewey Watson (born April 6, 1928) is an American molecular biologist, best known as one of the co-discoverers of the structure of DNA. Watson, Francis Crick, and Maurice Wilkins were awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material".[3] He studied at the University of Chicago and Indiana University and subsequently worked at the University of Cambridge's Cavendish Laboratory in England where he first met Francis Crick. Image File history File links Download high-resolution version (963x1200, 119 KB) James D. Watson, source: http://www. ... is the 96th day of the year (97th in leap years) in the Gregorian calendar. ... Year 1928 (MCMXXVIII) was a leap year starting on Sunday (link will display full calendar) of the Gregorian calendar. ... For other uses, see Chicago (disambiguation). ... This article is about the U.S. State. ... For other uses of terms redirecting here, see US (disambiguation), USA (disambiguation), and United States (disambiguation) Motto In God We Trust(since 1956) (From Many, One; Latin, traditional) Anthem The Star-Spangled Banner Capital Washington, D.C. Largest city New York City National language English (de facto)1 Demonym American... For other uses of terms redirecting here, see US (disambiguation), USA (disambiguation), and United States (disambiguation) Motto In God We Trust(since 1956) (From Many, One; Latin, traditional) Anthem The Star-Spangled Banner Capital Washington, D.C. Largest city New York City National language English (de facto)1 Demonym American... The United Kingdom of Great Britain and Northern Ireland is a country in western Europe, and member of the Commonwealth of Nations, the G8, the European Union, and NATO. Usually known simply as the United Kingdom, the UK, or (inaccurately) as Great Britain or Britain, the UK has four constituent... Molecular biology is the study of biology at a molecular level. ... Salvador Edward Luria (August 13, 1912 – February 6, 1991) was an Italian microbiologist whose pioneering work on phages helped open up molecular biology. ... Image File history File links Nobel_prize_medal. ... The structure of part of a DNA double helix Deoxyribonucleic acid, or DNA, is a nucleic acid molecule that contains the genetic instructions used in the development and functioning of all known living organisms. ... Molecular biology is the study of biology at a molecular level. ... Image File history File links Nobel_prize_medal. ... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ... For information about the band, see Atheist (band). ... is the 96th day of the year (97th in leap years) in the Gregorian calendar. ... Year 1928 (MCMXXVIII) was a leap year starting on Sunday (link will display full calendar) of the Gregorian calendar. ... Molecular biology is the study of biology at a molecular level. ... The structure of part of a DNA double helix Deoxyribonucleic acid, or DNA, is a nucleic acid molecule that contains the genetic instructions used in the development and functioning of all known living organisms. ... Francis Harry Compton Crick OM FRS (8 June 1916 – 28 July 2004), (Ph. ... Maurice Hugh Frederick Wilkins CBE FRS (15 December 1916 – 5 October 2004) was a New Zealand-born British molecular biologist, and Nobel Laureate who contributed research in the fields of phosphorescence, radar, isotope separation, and X-ray diffraction. ... Emil Adolf von Behring was the first person to receive the Nobel Prize in Physiology or Medicine, for his work on the treatment of diphtheria. ... Look up nucleic acid in Wiktionary, the free dictionary. ... The University of Chicago is a private co-educational university located in Chicago, Illinois. ... Indiana University, founded in 1820, is a nine-campus university system in the state of Indiana. ... The University of Cambridge is the second-oldest university in the English-speaking world (after Oxford). ... Plaque, at old site Entrance, old site, Free School Lane The Cavendish Laboratory is the University of Cambridges Department of Physics, and is part of the universitys School of Physical Sciences. ...


In 1956 he became a faculty member of Harvard University's Biological Laboratories until 1976, but in 1968 served as Director of Cold Spring Harbor Laboratory on Long Island, New York and shifted its research emphasis to the study of cancer. In 1994 he became its President for ten years, and then subsequently served as its Chancellor until 2007. Between 1988 and 1992 he was associated with the National Institutes of Health, helping to establish the Human Genome Project. He has written many science books, including the seminal textbook "The Molecular Biology of the Gene" (1965) and his bestselling book "The Double Helix" (1968) about the DNA Structure discovery. Harvard redirects here. ... The Cold Spring Harbor Laboratory (CSHL) is a research and educational institution, consisting of science laboratories located in Cold Spring Harbor, New York on Long Island, USA. The Laboratory has research programs focusing on cancer, neurobiology, plant genetics, genomics and bioinformatics, and has a broad educational mission, including the recently... National Institutes of Health Building 50 at NIH Clinical Center - Building 10 The National Institutes of Health (NIH) is an agency of the United States Ministry of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. ... The Human Genome Project (HGP) is an international scientific research project. ...

Contents

Biography

Watson was born in Chicago, Illinois, on April 6, 1928, the son of a businessman, also named James Dewey Watson, and Margaret Jean Mitchell [4]. His father was of midwestern English descent[5]. His mother's father Lauchlin Mitchell, a tailor, was from Glasgow, Scotland, and her mother, Lizzie Gleason, was the child of Irish parents from Tipperary[6]. Watson was fascinated with bird watching, a hobby he shared with his father.[7] Watson appeared on Quiz Kids, a popular radio show that challenged precocious youngsters to answer questions.[8] Thanks to the liberal policy of University president Robert Hutchins, he enrolled at the University of Chicago at the age of 15.[9] After reading Erwin Schrödinger's book What Is Life? in 1946, Watson changed his professional ambitions from the study of ornithology to genetics.[10] He earned his B.S. in Zoology from the University of Chicago in 1947. In his autobiography, Avoid Boring People, Watson describes the University of Chicago as an idyllic academic institution where he was instilled with the capacity for critical thought and an ethical compulsion not to suffer fools who impeded his search for truth, in contrast to his description of his later work at Harvard University.[11] Flag Seal Nickname: The Windy City Motto: Urbs In Horto (Latin: City in a Garden), I Will Location Location in Chicagoland and northern Illinois Coordinates , Government Country State Counties United States Illinois Cook, DuPage Mayor Richard M. Daley (D) Geographical characteristics Area     City 606. ... is the 96th day of the year (97th in leap years) in the Gregorian calendar. ... Year 1928 (MCMXXVIII) was a leap year starting on Sunday (link will display full calendar) of the Gregorian calendar. ... This article is about the Midwestern region in the United States. ... This article is about the English as an ethnic group and nation. ... A tailor attending to a customer in Hong Kong. ... For other uses, see Glasgow (disambiguation). ... This article is about the country. ... WGS-84 (GPS) Coordinates: , Irish grid reference R889358 Statistics Province: Munster County: Elevation: 166 m (544 ft) Population (2002)  - Town:  - Environs:   4,546  418 Tipperary (Irish: Tiobraid Árann) is the name of a county, and a town in the south-west of that county. ... Sam Bermans 1947 NBC promotional caricatures of the Quiz Kids and host Joe Kelly. ... Robert Maynard Hutchins (January 17, 1899, Brooklyn, New York – May 17, 1977, Santa Barbara, California) was an educational philosopher, a president (1929–1945) of the University of Chicago and its chancellor (1945–1951). ... For other uses, see University of Chicago (disambiguation). ... Schrödinger in 1933, when he was awarded the Nobel Prize in Physics Bust of Schrödinger, in the courtyard arcade of the main building, University of Vienna, Austria. ... What is Life? is a non-fiction book on science for the lay reader written by physicist Erwin Schrödinger (ISBN 0521427088). ... This article is about the field of zoology. ... This article is about the general scientific term. ... Zoology (from Greek: ζῴον, zoion, animal; and λόγος, logos, knowledge) is the biological discipline which involves the study of animals. ... For other uses, see University of Chicago (disambiguation). ... Harvard redirects here. ...


He was attracted to the work of Salvador Luria. Luria eventually shared a Nobel Prize for his work on the Luria-Delbrück experiment, which concerned the nature of genetic mutations. Luria was part of a distributed group of researchers who were making use of the viruses that infect bacteria, called bacteriophages. Luria and Max Delbrück were among the leaders of this new "Phage Group", an important movement of geneticists from experimental systems such as Drosophila towards microbial genetics. Early in 1948 Watson began his Ph.D. research in Luria's laboratory at Indiana University and that spring he got to meet Delbrück in Luria's apartment and again that summer during Watson's first trip to the Cold Spring Harbor Laboratory (CSHL).[12] The Phage Group was the intellectual medium within which Watson became a working scientist. Importantly, the members of the Phage Group had a sense that they were on the path to discovering the physical nature of the gene. In 1949 Watson took a course with Felix Haurowitz that included the conventional view of that time: that proteins were genes and able to replicate themselves.[13] The other major molecular component of chromosomes, DNA, was thought by many to be a "stupid tetranucleotide", serving only a structural role to support the proteins. However, even at this early time, Watson, under the influence of the Phage Group, was aware of the work of Oswald Avery which suggested that DNA was the genetic molecule. Watson's research project involved using X-rays to inactivate bacterial viruses ("phage").[14] He gained his Ph.D. in Zoology at Indiana University in 1950 (at age 22). Salvador Edward Luria (August 13, 1912 – February 6, 1991) was an Italian microbiologist whose pioneering work on phages helped open up molecular biology. ... The two possibilities tested by the Luria-Delbrück experiment. ... For linguistic mutation, see Apophony. ... This article is about biological infectious particles. ... Phyla Actinobacteria Aquificae Chlamydiae Bacteroidetes/Chlorobi Chloroflexi Chrysiogenetes Cyanobacteria Deferribacteres Deinococcus-Thermus Dictyoglomi Fibrobacteres/Acidobacteria Firmicutes Fusobacteria Gemmatimonadetes Lentisphaerae Nitrospirae Planctomycetes Proteobacteria Spirochaetes Thermodesulfobacteria Thermomicrobia Thermotogae Verrucomicrobia Bacteria (singular: bacterium) are unicellular microorganisms. ... ... Max Delbrück in the early 1940s at Vanderbilt University. ... The phage group (sometimes called the American Phage Group) was an informal network of biologists centered around Max Delbrück that contributed heavily to bacterial genetics and the origins of molecular biology in the mid-20th century. ... Type species Drosophila funebris (Fabricius, 1787) Drosophila is a genus of small flies, belonging to the family Drosophilidae, whose members are often called fruit flies, or more appropriately vinegar flies, wine flies, pomace flies, grape flies, and picked fruit-flies, a reference to the characteristic of many species to linger... The Cold Spring Harbor Laboratory (CSHL) is a research and educational institution, consisting of science laboratories located in Cold Spring Harbor, New York on Long Island, USA. The Laboratory has research programs focusing on cancer, neurobiology, plant genetics, genomics and bioinformatics, and has a broad educational mission, including the recently... For other uses, see Gene (disambiguation). ... A representation of the 3D structure of myoglobin showing coloured alpha helices. ... For information about chromosomes in genetic algorithms, see chromosome (genetic algorithm). ... Oswald Theodore Avery in 1937 Oswald Theodore Avery (October 21, 1877–2 February 1955) was a Canadian-born American physician and medical researcher. ... In the NATO phonetic alphabet, X-ray represents the letter X. An X-ray picture (radiograph) taken by Röntgen An X-ray is a form of electromagnetic radiation with a wavelength approximately in the range of 5 pm to 10 nanometers (corresponding to frequencies in the range 30 PHz... This article or section does not cite its references or sources. ...


Watson then went to Copenhagen in September 1950 for a year of postdoctoral research, first heading to the laboratory of biochemist Herman Kalckar.[7] Kalckar was interested in the enzymatic synthesis of nucleic acids, and wanted to use phage as an experimental system. Watson, however, wanted to explore the structure of DNA, and his interests did not coincide with Kalckar's.[15] After working part of the year with Kalcker, Watson spent the remainder of his time in Copenhagen conducting experiments with microbial physiologist Ole Maaloe, then a member of the Phage Group.[16] The experiments, which Watson had learned of during the previous summer's Cold Spring Harbor phage conference, included the use of radioactive phosphate as a tracer to determine which molecular components of phage particles actually infect the target bacteria during viral infection.[15] The intention was to determine whether protein or DNA was the genetic material, but upon consultation with Max Delbrück,[15] they determined that their results were inconclusive and could not specifically identify the newly labeled molecules as DNA.[17] Watson never developed a constructive interaction with Kalckar, but he did accompany Kalckar to a meeting in Italy where Watson saw Maurice Wilkins talk about his X-ray diffraction data for DNA.[7] Watson was now certain that DNA had a definite molecular structure that could be solved.[18] For other uses, see Copenhagen (disambiguation). ... Herman Moritz Kalckar (1908 -1991) was a Danish biochemist who pioneered the study of cellular respiration. ... Max Delbrück in the early 1940s at Vanderbilt University. ...


In 1951 the chemist Linus Pauling published his model of the protein alpha helix, a result that grew out of Pauling's relentless efforts in X-ray crystallography and molecular model building. After obtaining some results from his phage and other experimental research conducted at Indiana University, Statens seruminstitute (Denmark), Cold Spring Harbor Laboratory, and the California Institute of Technology, Watson now had the desire to learn to perform X-ray diffraction experiments so that he could work to determine the structure of DNA. That summer, Luria met John Kendrew and arranged for a new postdoctoral research project for Watson in England.[7] Linus Carl Pauling (February 28, 1901 – August 19, 1994) was an American scientist, peace activist, author and educator of German ancestry. ... Side view of an α-helix of alanine residues in atomic detail. ... This article or section does not cite its references or sources. ...


In 1968, Watson married Elizabeth Lewis and became the Director of Cold Spring Harbor Laboratory. Between 1970 and 1972 Watson's two sons were born and by 1974 the young family made CSHL their permanent residence. Watson served as the Laboratory's Director and President for 35 years, and later assumed the role of Chancellor. In October 2007 Watson resigned as a result of controversial remarks about race made to the press. The Cold Spring Harbor Laboratory (CSHL) is a research and educational institution, consisting of science laboratories located in Cold Spring Harbor, New York on Long Island, USA. The Laboratory has research programs focusing on cancer, neurobiology, plant genetics, genomics and bioinformatics, and has a broad educational mission, including the recently...


Structure of DNA

James D. Watson
Discovery of the DNA Double Helix

James Watson in the lab.
William Astbury Oswald Avery
Francis Crick Erwin Chargaff
Jerry Donohue Rosalind Franklin
Phoebus Levene Linus Pauling
Erwin Schrödinger Alec Stokes
James Watson Maurice Wilkins

In October 1951, James Watson moved to Clare College, Cambridge and started at the Cavendish Laboratory, the physics department of the University of Cambridge, with a fellowship from the National Foundation for Infantile Paralysis. Here he shared an office with Francis Crick where they found they had similar scientific interests and initiated a collaboration to discover the structure of DNA. Crick soon solved the mathematical equations that govern helical diffraction theory; Watson knew all of the key DNA results of the Phage Group.[19] The Molecular structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid was an article published by James D. Watson and Francis Crick in the scientific journal Nature in its 171st volume on page 737-738 (dated April 25, 1953). ... Image File history File links Download high-resolution version (963x1200, 119 KB) James D. Watson, source: http://www. ... William Astbury (1898-1961) was an English biochemist who made X-ray diffraction studies of nucleic acid in 1937. ... Oswald Theodore Avery in 1937 Oswald Theodore Avery (October 21, 1877–2 February 1955) was a Canadian-born American physician and medical researcher. ... Francis Harry Compton Crick OM FRS (8 June 1916 – 28 July 2004), (Ph. ... // Erwin Chargaff (Czernowitz, August 11, 1905 – New York City, USA, June 20, 2002) was an Austrian biochemist who emigrated to the United States during the Nazi era. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... Rosalind Elsie Franklin (25 July 1920 Kensington, London – 16 April 1958 Chelsea, London) was an English biophysicist and X-ray crystallographer who made important contributions to the understanding of the fine structures of DNA, viruses, coal and graphite. ... Molecular diagram of a hypothetical tetranucleotide, as proposed (incorrectly) by Phoebus Levene around 1910. ... Linus Carl Pauling (February 28, 1901 – August 19, 1994) was an American scientist, peace activist, author and educator of German ancestry. ... Schrödinger in 1933, when he was awarded the Nobel Prize in Physics Bust of Schrödinger, in the courtyard arcade of the main building, University of Vienna, Austria. ... Alec Stokes (Alexander Rawson Stokes, June 27, 1919–February 5, 2003) was one of the key contributors in the original DNA research team at Kings College London. ... Maurice Hugh Frederick Wilkins CBE FRS (15 December 1916 – 5 October 2004) was a New Zealand-born British molecular biologist, and Nobel Laureate who contributed research in the fields of phosphorescence, radar, isotope separation, and X-ray diffraction. ... College name Clare College Named after Elizabeth de Clare Established 1326 Previously named University Hall (1326-1338) Clare Hall (1338-1856) Location Trinity Lane Admittance Men and women Master Prof. ... Plaque, at old site Entrance, old site, Free School Lane The Cavendish Laboratory is the University of Cambridges Department of Physics, and is part of the universitys School of Physical Sciences. ... The University of Cambridge (often Cambridge University), located in Cambridge, England, is the second-oldest university in the English-speaking world and has a reputation as one of the most prestigious universities in the world. ... March of Dimes is the name of a United States health charity, whose mission is to improve the health of babies. ... Francis Harry Compton Crick OM FRS (8 June 1916 – 28 July 2004), (Ph. ...


In late 1951 Crick and Watson began a series of informal exchanges with Maurice Wilkins during which some of Rosalind Franklin's findings were given to Watson and Crick by Wilkins without Franklin's permission or knowledge. In November, Watson attended a seminar by Franklin. She spoke about the X-ray diffraction data she had collected with Raymond Gosling at King's College London. The data indicated that DNA was a helix of some sort. Soon after this seminar, Watson and Crick constructed an incorrect molecular model of DNA in which the phosphate backbones were on the inside of the structure. Franklin asserted that the phosphates almost certainly were on the outside, not the inside. Watson and Crick eventually came to see that she was right and used this information in their final determination of the helical structure. In 1952, the final details of the chemical structure of the DNA backbone were determined by biochemists like Alexander Todd. Rosalind Elsie Franklin (25 July 1920 Kensington, London – 16 April 1958 Chelsea, London) was an English biophysicist and X-ray crystallographer who made important contributions to the understanding of the fine structures of DNA, viruses, coal and graphite. ... The joke funeral card in the names of Rosalind Franklin and Raymond Gosling Raymond Gosling is a distinguished scientist who worked with both Maurice Wilkins and Rosalind Franklin at Kings College London in deducing the structure of DNA. He was born in 1926 and attended school in Wembley. ... For other uses, see Kings College. ... Alexander Robertus Todd, Baron Todd, PC , OM , FRS (2 October 1907 – 10 January 1997) was a Scottish biochemist whose research on the structure and synthesis of nucleotides, nucleosides, and nucleotide coenzymes gained him the 1957 Nobel Prize for Chemistry. ...


During 1952, Crick and Watson had been asked not to work on making molecular models of the structure of DNA.[20] Instead, Watson's official assignment was to perform X-ray diffraction experiments on tobacco mosaic virus. Tobacco mosaic virus was the first virus to be identified (1886) and purified (1935). Since electron microscopy revealed that virus crystals form inside infected plants, it made sense to isolate this virus for study by X-ray crystallography. Early X-ray diffraction images for tobacco mosaic virus had been collected before World War II. By 1954, Watson had deduced from his X-ray diffraction images that the tobacco mosaic virus had a helical structure.[21] Despite his official assignment, the lure of solving the puzzle of DNA structure continued to tantalize Watson; with his friend Crick, he continued to think about how to determine the structure of DNA. This article does not cite any references or sources. ... An electron microscope is a type of microscope that uses electrons as a way to illuminate and create an image of a specimen. ... X-ray crystallography, also known as single-crystal X-ray diffraction, is the oldest and most common crystallographic method for determining the structure of molecules. ...


In April 1952, Watson's PhD research adviser, Luria, was to speak at a meeting in England. However, Luria was not allowed to travel due to cold war fears over his Marxist leanings. Watson used Luria's speaking slot to talk about his own work with radioactive DNA and the results of others in the Phage Group that indicated the genetic material of phages was DNA. It has been recorded that during this meeting Watson was discussing with others prior discoveries by other researchers such as the calculated width of the B-form DNA molecule as determined by X-ray diffraction studies. By 1952 estimates from X-ray data and electron microscopy agreed that the diameter of DNA was about 2 nanometers. Doctor of Philosophy, abbreviated Ph. ... Marxism is the political practice and social theory based on the works of Karl Marx, a 19th century philosopher, economist, journalist, and revolutionary, along with Friedrich Engels. ... The structure of part of a DNA double helix Deoxyribonucleic acid, or DNA, is a nucleic acid molecule that contains the genetic instructions used in the development and functioning of all known living organisms. ...


Watson and Crick benefited from three travel-related strokes of luck in 1952. First, Erwin Chargaff visited England in 1952 and inspired Watson and Crick to learn more about nucleotide biochemistry. There are four nucleobases: guanine (G), cytosine (C), adenine (A) and thymine (T) in DNA. The so-called Chargaff ratios experimental results indicated that the amount of G is equal to C and the amount of A is equal to T. Jerry Donohue explained to Watson and Crick the correct structures of the four bases. The second travel-related event was that Linus Pauling's plans to visit England were disrupted. His planned visit was canceled for political reasons and he never gained access to the King's College X-ray diffraction data for DNA until it was published in 1953. The third was when Chargaff and Pauling crossed the Atlantic together, they did not get along and Pauling avoided Chargaff all across the ocean when they could have compared notes on DNA's base pairs! // Erwin Chargaff (Czernowitz, August 11, 1905 – New York City, USA, June 20, 2002) was an Austrian biochemist who emigrated to the United States during the Nazi era. ... A nucleotide is a chemical compound that consists of 3 portions: a heterocyclic base, a sugar, and one or more phosphate groups. ... Adenine Guanine Thymine Cytosine ... Guanine is one of the five main nucleobases found in the nucleic acids DNA and RNA; the others being adenine, cytosine, thymine, and uracil. ... Cytosine is one of the 5 main nucleobases used in storing and transporting genetic information within a cell in the nucleic acids DNA and RNA. It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at... For the programming language Adenine, see Adenine (programming language). ... For the similarly-spelled vitamin compound, see Thiamine Thymine, also known as 5-methyluracil, is a pyrimidine nucleobase. ... Chargaffs rules state that DNA from any cell of all organisms should have a 1:1 ratio of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. ... To meet Wikipedias quality standards, this article or section may require cleanup. ...


In 1953, Crick and Watson were given permission by their lab director and Wilkins to again try to make a structural model of DNA. At this time, Crick and Watson became aware of a research progress report containing some of Franklin's findings. This report contained the data that she had previously discussed in her research seminar of November 1951. Crick and Watson continued to make use of Franklin's results in their thinking about the structure of DNA.


Breakthrough

DNA double helix as envisioned by Watson and Crick.
DNA double helix as envisioned by Watson and Crick.

Watson's key contribution was in discovering the nucleotide base pairs, the key to the structure and function of DNA. This key discovery was made in the Pauling "tradition", by playing with molecular models. Image File history File links Download high resolution version (799x2000, 915 KB) Summary An overview of the structure of DNA. Created by Michael Ströck (mstroeck) on February 8, 2006. ... Image File history File links Download high resolution version (799x2000, 915 KB) Summary An overview of the structure of DNA. Created by Michael Ströck (mstroeck) on February 8, 2006. ... Base pairs, of a DNA molecule. ...

A GC base pair demonstrating three intermolecular hydrogen bonds
A GC base pair demonstrating three intermolecular hydrogen bonds
An AT base pair demonstrating two intermolecular hydrogen bonds
An AT base pair demonstrating two intermolecular hydrogen bonds

Since he would have to wait for the Cavendish machine shop to make tin models of the four nucleobases, Watson, on February 28, 1953 made a molecule model of each using a straight edge, an exacto knife, white cardboard and paste. These molecules are all flat in their ring structures, so Watson could slide the cardboard models around on a table and examine how they might interact and fit together. After looking at the possible arrangements of his cardboard molecule models, Watson soon realized that the larger two-ring A and G nucleobases (technically referred to as purines) could be paired with the smaller one-ring T and C nucleobases, known as pyrimidines. Watson examined the possibility of hydrogen bonds between the pairs of purines and pyrimidines. After moving the A and T molecules around on the table he sat at, he brought together the distal (relative to its five-member ring) nitrogen of the A and the correct nitrogen-based hydrogen of T. Fortunately, the A and T were lying on the table both "face up" in that they were in the orientation as they occur in DNA and Watson then noticed the possibility of the second hydrogen bond involving an oxygen atom. He quickly saw that the other pair, C's nitrogen and G's nitrogen-based hydrogen had a similar relationship and that those two molecules formed three such bonds. As the accompanying diagram indicates, all five hydrogens involved have a covalent bond to a nitrogen (which has no "double" bond) and form the weaker hydrogen bond with either a nitrogen or an oxygen that each have one double valence bond to a carbon atom. Image File history File links This is a lossless scalable vector image. ... Image File history File links This is a lossless scalable vector image. ... An example of a quadruple hydrogen bond between a self-assembled dimer complex reported by Meijer and coworkers. ... Image File history File links This is a lossless scalable vector image. ... Image File history File links This is a lossless scalable vector image. ... An example of a quadruple hydrogen bond between a self-assembled dimer complex reported by Meijer and coworkers. ... A lathe is a common tool used in machining. ... is the 59th day of the year in the Gregorian calendar. ... Year 1953 (MCMLIII) was a common year starting on Thursday (link will display full calendar) of the Gregorian calendar. ... Purine (1) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. ... Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring [1]. It is isomeric with two other forms of diazine. ... An example of a quadruple hydrogen bond between a self-assembled dimer complex reported by Meijer and coworkers. ... Covalent redirects here. ...


Watson then saw that the two pairs could be superimposed on each other with similar overall structure. In particular, the hexagonal rings were equidistant and the relative orientations of the five-member rings of the "big" molecules, A and G were the same. The nitrogens with the "squiggly" lines are the ones that attach, as "ladder rungs", to the helical backbone and that these nitrogen atoms are equidistant and also superimpose in the two pairs, allowing the helical structure to be smooth. Watson sensed that too many pieces were falling into place for this to be anything but the answer. He was correct. The base pairs discovered by Watson were consistent with the biochemical data Chargaff had already published.


Nobel Prize

Diagram showing the key structural components in the chemical structure of DNA. The actual 3D structure is shown at DNA.
Diagram showing the key structural components in the chemical structure of DNA. The actual 3D structure is shown at DNA.

Watson and Crick proceeded to deduce the double helix structure of DNA which they submitted to the journal Nature and was subsequently published on April 25, 1953.[22] Watson, Crick, and Wilkins were awarded the Nobel Prize in Physiology or Medicine in 1962 for their research on the structure of nucleic acids.[3] Some regret that Franklin did not live long enough to share in the Nobel Prize.[23] Watson mentions in his autobiography, Avoid Boring People, that he was refused a $1,000 raise in salary after winning the Nobel. [11] Image File history File links No higher resolution available. ... Image File history File links No higher resolution available. ... The structure of part of a DNA double helix Deoxyribonucleic acid, or DNA, is a nucleic acid molecule that contains the genetic instructions used in the development and functioning of all known living organisms. ... The Double-Helix are an alien race in the Wing Commander science fiction series. ... Nature is a prominent scientific journal, first published on 4 November 1869. ... is the 115th day of the year (116th in leap years) in the Gregorian calendar. ... Year 1953 (MCMLIII) was a common year starting on Thursday (link will display full calendar) of the Gregorian calendar. ...


The Double Helix

In 1968 Watson wrote The Double Helix, one of the Modern Library's 100 best non-fiction books. The account is the sometimes painful story of not only the discovery of the structure of DNA, but the personalities, conflicts and controversy surrounding their work. James Watson The Double Helix: A Personal Account of the Discovery of the Structure of DNA is an autobiographical account of the discovery of structure of DNA. It was written by James D. Watson and published in 1968. ... The Modern Library, a current division of Random House publishers, was founded in 1917 by Albert Boni and Horace Liveright. ...


Controversy attended the publication of the book. Harvard professor Richard Lewontin wrote that the book had "debased the currency of his [Watson's] own life", and molecular biologist Robert L. Sinsheimer described Watson's portrayal of science as a "clawing climb up a slippery slope, impeded by the authority of fools, to be made with cadged data ... with malice toward most, and charity toward none." [11] It was originally to be published by Harvard University Press, but after objections from both Francis Crick and Maurice Wilkins, among others, Watson's home university where he had been a member of the biology faculty since 1955, dropped the book and it was instead published by a commercial publisher, an incident which caused some scandal. Watson's original title was to have been "Honest Jim," in part to raise the ethical questions of bypassing Franklin to gain access to her X-ray diffraction data before they were published. If all that mattered was beating Pauling to the structure of DNA, then Franklin's cautious approach to analysis of the X-ray data was simply an obstacle that Watson needed to run around. Wilkins and others were there at the right time to help Watson and Crick do so. Richard Lewontin Richard Charles Dick Lewontin (born March 29, 1929) is an American evolutionary biologist, geneticist and social commentator. ... Molecular biology is the study of biology at a molecular level. ... The Harvard University Press is a publishing house, a division of Harvard University, that is highly respected in academic publishing. ... Francis Harry Compton Crick OM FRS (8 June 1916 – 28 July 2004), (Ph. ... Maurice Hugh Frederick Wilkins CBE FRS (15 December 1916 – 5 October 2004) was a New Zealand-born British molecular biologist, and Nobel Laureate who contributed research in the fields of phosphorescence, radar, isotope separation, and X-ray diffraction. ...


The Double Helix changed the way the public viewed scientists and the way they work.[24] In the same way, Watson's first textbook, The Molecular Biology of the Gene, set a new standard for textbooks, particularly through the use of concept heads—brief declarative subheadings. Its style has been emulated by almost all succeeding textbooks. His next great success was Molecular Biology of the Cell, although here his role was more that of coordinator of an outstanding group of scientist-writers. His third textbook was Recombinant DNA, which used the ways in which genetic engineering has brought us so much new information about how organisms function. the textbooks are still in print. Elements of genetic engineering Genetic engineering, recombinant DNA technology, genetic modification/manipulation (GM) and gene splicing are terms that are applied to the direct manipulation of an organisms genes. ...


Genome project

In 1989, Watson's achievement and success led to his appointment as the Head of the Human Genome Project at the National Institutes of Health, a position he held until April 10, 1992.[25] Watson left the Genome Project after conflicts with the new NIH Director, Bernadine Healy. Watson was opposed to Healy's attempts to acquire patents on gene sequences, and any ownership of the "laws of nature." Two years before stepping down from the Genome Project, he had stated his opinion on this long and ongoing controversy which he saw as an illogical barrier to research; he said, "The nations of the world must see that the human genome belongs to the world's people, as opposed to its nations." He left within weeks of the 1992 announcement that the NIH would be applying for patents on brain-specific cDNAs.[26] In 1994, Watson became President of CSHL. Francis Collins took over the role as Director of the Human Genome Project. He became the second person [27] to publish his fully sequenced genome online, after it was presented to him on May 31, 2007 by 454 Life Sciences Corporation in collaboration with scientists at the Human Genome Sequencing Center, Baylor College of Medicine. "'I am putting my genome sequence on line to encourage the development of an era of personalized medicine, in which information contained in our genomes can be used to identify and prevent disease and to create individualized medical therapies,' said CSHL Chancellor Watson."[28] The Human Genome Project (HGP) is an international scientific research project. ... National Institutes of Health Building 50 at NIH Clinical Center - Building 10 The National Institutes of Health (NIH) is an agency of the United States Ministry of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. ... National Institutes of Health Building 50 at NIH Clinical Center - Building 10 The National Institutes of Health (NIH) is an agency of the United States Ministry of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. ... Dr. Bernadine Patricia Healy (b. ... The Cold Spring Harbor Laboratory (CSHL) is a research and educational institution, consisting of science laboratories located in Cold Spring Harbor, New York on Long Island, USA. The Laboratory has research programs focusing on cancer, neurobiology, plant genetics, genomics and bioinformatics, and has a broad educational mission, including the recently... This article needs to be wikified. ...


Awards

  • Albert Lasker Award for Basic Medical Research[29]
  • Benjamin Franklin Medal for Distinguished Achievement in the Sciences[30]
  • Charles A. Dana Award
  • Copley Medal of the Royal Society
  • Eli Lilly Award in Biochemistry
  • Fellow of the New York Academy of Sciences
  • Gairdner Award
  • Heald Award
  • Honorary Knight of the British Empire
  • John Collins Warren Prize of the Massachusetts General Hospital
  • John J. Carty Gold Medal of the National Academy of Sciences
  • Kaul Foundation Award for Excellence
  • Liberty Medal[31]

The Albert Lasker Award for Basic Medical Research is awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease. ... The Philadelphia Liberty Medal is an annual award administered by the National Constitution Center of the United States to recognize leadership in the pursuit of freedom. ... National Medal of Science The National Medal of Science is an honor given by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social sciences, biology, chemistry, engineering, mathematics and physics. ... Emil Adolf von Behring was the first person to receive the Nobel Prize in Physiology or Medicine, for his work on the treatment of diphtheria. ... The Presidential Medal of Freedom The Presidential Medal of Freedom is one of the two highest civilian awards in the United States and is bestowed by the President of the United States (the other award which is considered its equivalent is the Congressional Gold Medal, which is bestowed by an...

Career

At Harvard University, starting in 1956, Watson achieved a series of academic promotions from Assistant Professor, to Associate Professor to full Professor of Biology. He championed a switch in focus for the school from classical biology to molecular biology, stating that disciplines such as ecology, developmental biology, taxonomy, physiology, etc. had stagnated and could only progress once the underlying disciplines of molecular biology and biochemistry had elucidated their underpinnings, going so far as to discourage their study by students. He left the school in 1976.[11] The history of biology dates as far back as the rise of various civilization as classic philosophers did their own ways of biology as a system of understanding life. ... Molecular biology is the study of biology at a molecular level. ... For the journal, see Ecology (journal). ... Views of a Foetus in the Womb, Leonardo da Vinci, ca. ... For the science of classifying living things, see alpha taxonomy. ... This article or section does not cite any references or sources. ... Wöhler observes the synthesis of urea. ...


Watson joined the staff of Cold Spring Harbor Laboratory in 1968. In a retrospective summary of his accomplishments there, Bruce Stillman, the laboratory's president said, "Jim Watson created a research environment that is unparalleled in the world of science." It was "under his direction [that the Lab has] made major contributions to understanding the genetic basis of cancer." Generally in his roles as Director, President, and Chancellor, Watson led CSHL to its present day mission, which is "dedicat[ion] to exploring molecular biology and genetics in order to advance the understanding and ability to diagnose and treat cancers, neurological diseases, and other causes of human suffering." In October, 2007, Watson was suspended following criticism of views on race and intelligence attributed to him, and a week later, on the 25th, he retired at the age of 79 from Cold Spring Harbor Laboratory from what the lab called "nearly 40 years of distinguished service", [35] In a statement, Watson attributed his retirement to his age, and circumstances that he could never have anticipated or desired.[36] is the 291st day of the year (292nd in leap years) in the Gregorian calendar. ... is the 298th day of the year (299th in leap years) in the Gregorian calendar. ...


In January 2007, Watson accepted the invitation of Leonor Beleza, president of the Champalimaud Foundation, to become the head of the foundation's scientific council, an advisory organ. He will be in charge of selecting the remaining council members.[37] Maria Leonor Couceiro Pizarro Beleza de Mendonça Tavares, is a Portuguese politican, member of the Social Democratic Party. ... The Champalimaud Foundation is a private Portuguese biomedical research foundation. ...


As of 2008, Watson is the Institute advisor for the newly-formed Allen Institute for Brain Science [38]. The Institute, located in Seattle, Washington, was founded in 2003 by Philanthropists Paul G. Allen and Jody Allen Patton as a 501(c)(3) nonprofit corporation and medical research organization. A multidisciplinary group of neuroscientists, molecular biologists, informaticists, engineers, mathematicians, statisticians, and computational biologists have been brought together to form the scientific core of the Allen Institute. Utilizing the mouse model system, these fields have joined together to investigate expression of 20,000 genes in the adult mouse brain and to map gene expression to a cellular level beyond neuroanatomic boundaries. The data generated from this joint effort is contained in the publicly available Allen Brain Atlas application located at www.brain-map.org. Upon completion of the Allen Brain Atlas, this consortium of scientists will pursue additional questions to further our understanding of neuronal circuitry and the neuroanatomic framework that defines the functionality of the brain. Seattle redirects here. ... For the capital city of the United States, see Washington, D.C.. For other uses, see Washington (disambiguation). ... For other persons named Paul Allen, see Paul Allen (disambiguation). ... 501(c) is a provision of the United States Internal Revenue Code (), listing 27 types of non-profit organizations exempt from some federal income taxes. ... It has been suggested that this article or section be merged into Nonprofit. ...


Honorary degrees received

For other uses, see University of Chicago (disambiguation). ... Indiana University, founded in 1820, is a nine-campus university system in the state of Indiana. ... Not to be confused with the University of Notre Dame Australia University of Notre Dame du Lac The University of Notre Dame (standard name; full legal name University of Notre Dame du Lac) is a Roman Catholic institution of higher learning located in Notre Dame, Indiana, USA adjacent to the... Long Island University (LIU) is a private university located on Long Island in the U.S. state of New York. ... Adelphi University is a private, nonsectarian university located in Garden City, in Nassau County, New York. ... Brandeis University is a private university located in Waltham, Massachusetts, United States. ... Albert Einstein College of Medicine logo For the engineering company, see AECOM The Albert Einstein College of Medicine (AECOM) is a graduate school of Yeshiva University. ... Hofstra University is a private, nonsectarian, coeducational institution of higher learning located in Hempstead, Long Island, New York (USA) founded in 1935 on the basis of the estate of wealthy lumber magnate William S. Hofstra (1861-1932) and his (second) wife Kate Mason (1854-1933). ... Harvard redirects here. ... Founders Hall Rockefeller University is a private university focusing primarily on graduate and postgraduate education research in the biomedical fields, located between 63rd and 68th Streets along York Avenue, on the Upper East Side of Manhattan island in New York City, New York. ... Clarkson College is a private college located in Omaha, Nebraska that offers undergraduate and graduate degrees in the health sciences. ... “Rutgers” redirects here. ... For other meanings of the word Bard, see Bard (disambiguation). ... Stellenbosch University is an internationally recognised university which is situated in the town of Stellenbosch, South Africa. ... Main Entrance Fairfield University is a private, co-educational undergraduate and masters level university located in Fairfield, Connecticut, in the New England region of the United States. ... The University of Cambridge (often Cambridge University), located in Cambridge, England, is the second-oldest university in the English-speaking world and has a reputation as one of the most prestigious universities in the world. ...

Professional & honorary affiliations

  • American Academy of Arts and Sciences
  • American Association for Cancer Research
  • American Philosophical Society
  • American Society of Biological Chemists
  • Atheneum (London)
  • Cambridge University (Honorary Fellow, Clare College)
  • Danish Academy of Arts and Sciences
  • National Academy of Sciences
  • Oxford University (Newton-Abraham Visiting Professor)
  • Presidential Medal of Freedom[34]
  • Royal Society (London)
  • Russian Academy of Sciences

Political activism

During his tenure as a professor at Harvard, Watson participated in several political protests:

  • Vietnam War: While a professor at Harvard University, Watson, along with "12 Faculty members of the department of Biochemistry and Molecular Biology" including one other Nobel prize winner, spearheaded a resolution for "the immediate withdrawal of U.S. forces' from Vietnam."[39]
  • Nuclear proliferation and environmentalism: In 1975, on the "thirtieth anniversary of the bombing of Hiroshima," Watson along with "over 2000 scientists and engineers" spoke out against nuclear proliferation to President Ford in part because of the "lack of a proven method for the ultimate disposal of radioactive waste" and because "The writers of the declaration see the proliferation of nuclear plants as a major threat to American liberties and international safety because they say safeguard procedures are inadequate to prevent terrorist theft of commercial reactor-produced plutonium."[40]

Combatants Republic of Vietnam United States Republic of Korea Thailand Australia New Zealand The Philippines National Front for the Liberation of South Vietnam Democratic Republic of Vietnam People’s Republic of China Democratic Peoples Republic of Korea Strength US 1,000,000 South Korea 300,000 Australia 48,000... World map with nuclear weapons development status represented by color. ... The historic Blue Marble photograph, which helped bring environmentalism to the public eye. ...

Controversies

James Watson (February, 2003)
James Watson (February, 2003)

Watson's sometimes abrasive and aggressive personality (once described by E. O. Wilson as "the most unpleasant human being I had ever met"[11]) has made him the subject of several controversies; the controversy over his book The Double Helix was merely one such example. In his autobiography, Avoid boring People, he describes his academic colleagues as "dinosaurs", "deadbeats", "fossils", "has-beens", "mediocre", and "vapid".[11] Image File history File linksMetadata James_Watson. ... Image File history File linksMetadata James_Watson. ... Edward Osborne Wilson (born June 10, 1929) is an American biologist (Myrmecology, a branch of entomology), researcher (sociobiology, biodiversity), theorist (consilience, biophilia), and naturalist (conservationism). ...


Use of King's College results

An enduring controversy has been generated by Watson and Crick's use of DNA X-ray diffraction data collected by Rosalind Franklin and Raymond Gosling. The controversy arose from the fact that some of Franklin's unpublished data was used by Watson and Crick in their construction of the double helix model of DNA.[20] Franklin's experimental results provided estimates of the water content of DNA crystals and these results were consistent with the two sugar-phosphate backbones being on the outside of the molecule. Franklin personally told Crick and Watson that the backbones had to be on the outside. Her identification of the space group for DNA crystals revealed to Crick that the two DNA strands were antiparallel. The X-ray diffraction images collected by Gosling and Franklin provided the best evidence for the helical nature of DNA. Franklin's experimental work thus proved crucial in Watson and Crick's discovery. Watson and Crick had three sources for Franklin's unpublished data: 1) her 1951 seminar, attended by Watson, 2) discussions with Wilkins, who worked in the same laboratory with Franklin, 3) a research progress report that was intended to promote coordination of Medical Research Council-supported laboratories. Watson, Crick, Wilkins and Franklin all worked in MRC laboratories. Photo 51, an X-ray diffraction image of sodium salt of DNA. B configuration Photo 51 is the name given to an X-ray diffraction image of DNA taken by Rosalind Franklin in 1952[1] that was critical evidence[2] in identifying the structure of DNA.[3] The photo was... Rosalind Elsie Franklin (25 July 1920 Kensington, London – 16 April 1958 Chelsea, London) was an English biophysicist and X-ray crystallographer who made important contributions to the understanding of the fine structures of DNA, viruses, coal and graphite. ... The joke funeral card in the names of Rosalind Franklin and Raymond Gosling Raymond Gosling is a distinguished scientist who worked with both Maurice Wilkins and Rosalind Franklin at Kings College London in deducing the structure of DNA. He was born in 1926 and attended school in Wembley. ... The space group of a crystal is a mathematical description of the symmetry inherent in the structure. ... Two antiparallel molecules run side-by-side in opposite directions. ... Current MRC logo The Medical Research Council (MRC) is a UK organisation dedicated to promot[ing] the balanced development of medical and related biological research in the UK. // The MRC is one of seven Research Councils and is answerable to, although politically independent from, the Office of Science and Innovation...


Prior to publication of the double helix structure, Watson and Crick had little interaction with Franklin. Crick and Watson felt that they had benefited from collaborating with Wilkins. They offered him a co-authorship on the article that first described the double helix structure of DNA. Wilkins turned down the offer, a fact that may have led to the terse character of the acknowledgment of experimental work done at King's College in the eventual published paper. Rather than make any of the DNA researchers at King's College co-authors on the Watson and Crick double helix article, the solution that was arrived at was to publish two additional papers from King's College along with the helix paper. Biographer Brenda Maddox suggested that because of the importance of her work to Watson and Crick's model building, Franklin should have had her name on the original Watson and Crick manuscript.[41] Franklin may have never known the extent to which her unpublished data had helped in the double helix discovery. According to one critic, unprotected by libel laws, Watson's portrayal of Franklin in The Double Helix was negative, giving the appearance that she was Wilkins' assistant and was unable to interpret her own DNA data.[42] The biographer Brenda Maddox is a Harvard graduate who has lived for many years in the UK. Her biographies of Elizabeth Taylor, D.H. Lawrence, Nora Joyce, W.B. Yeats and Rosalind Franklin have been widely acclaimed. ... In English and American law, and systems based on them, libel and slander are two forms of defamation (or defamation of character), which is the tort or delict of making a false statement of fact that injures someones reputation. ...


In his book The Double Helix, Watson described being intimidated by Franklin and that they were unable to establish constructive scientific interactions during the time period when Franklin was doing DNA research. In the book's epilogue, written after Franklin's death, Watson acknowledges his early impressions of Franklin were often wrong, that she faced enormous barriers as a woman in the field of science even though her work was superb, and that it took years to overcome their bickering before appreciating Franklin's generosity and integrity. James Watson The Double Helix: A Personal Account of the Discovery of the Structure of DNA is an autobiographical account of the discovery of structure of DNA. It was written by James D. Watson and published in 1968. ...


A review of the handwritten correspondence from Franklin to Watson, located in the archives at Cold Spring Harbor Laboratory, reveals that the two scientists later had exchanges of constructive scientific correspondence. In fact, Franklin consulted with Watson on her Tobacco Mosaic Virus RNA research. Franklin's letters begin on friendly terms with "Dear Jim", and conclude with equally benevolent and respectful sentiments like "Best Wishes, Yours, Rosalind". As is typical with scientific research, each of the scientists published their own unique contributions to the discovery of the structure of DNA in separate articles, and all of the contributors published their findings in the same volume of Nature. These classic molecular biology papers are identified as: Watson J.D. and Crick F.H.C. "A Structure for Deoxyribose Nucleic Acid" Nature 171, 737-738 (1953),[22] Wilkins M.H.F., Stokes A.R. & Wilson, H.R. "Molecular Structure of Deoxypentose Nucleic Acids" Nature 171, 738-740 (1953),[43] Franklin R. and Gosling R.G. "Molecular Configuration in Sodium Thymonucleate" Nature 171, 740-741 (1953).[44] Franklin did not receive a Nobel Prize for her important contribution because the Nobel Prize is not awarded posthumously.[45]


The wording on the DNA sculpture (which was donated by James Watson) outside Clare College's Thirkill Court, Cambridge, England is:


On the base:

  • "These strands unravel during cell reproduction. Genes are encoded in the sequence of bases."
  • "The double helix model was supported by the work of Rosalind Franklin and Maurice Wilkins."

On the helices:

  • "The structure of DNA was discovered in 1953 by Francis Crick and James Watson while Watson lived here at Clare."
  • "The molecule of DNA has two helical strands that are linked by base pairs Adenine - Thymine or Guanine - Cytosine."

The aluminium sculpture stands fifteen feet high. It took a pair of technicians 1 fortnight (2 weeks) to build it. For the artist responsible it was an opportunity to create a monument that brings together the themes of science and nature; Charles Jencks, Sculptor said "It embraces the trees, you can sit on it and the ground grows up and it twists out of the ground. So it's truly interacting with living things like the turf, and that idea was behind it and I think it does celebrate life and DNA". Tony Badger, Master of Clare, said: "It is wonderful to have this lasting reminder of his achievements while he* was at Clare and the enormous contribution he* and Francis Crick have made to our understanding of life on earth." * James Watson.


Statement claiming links between race and intelligence

Watson signing autographs after a speech at Cold Spring Harbor Laboratory on April 30, 2007.
Watson signing autographs after a speech at Cold Spring Harbor Laboratory on April 30, 2007.
See also: Race and intelligence

On October 14, 2007, a biographical article written by one of Watson's former assistants[46], Charlotte Hunt-Grubbe, appeared in the Sunday Times Magazine in anticipation of his soon to be released, in the UK, memoir Avoid Boring People: Lessons from a Life in Science.[46] Image File history File linksMetadata No higher resolution available. ... Image File history File linksMetadata No higher resolution available. ... The Cold Spring Harbor Laboratory (CSHL) is a research and educational institution, consisting of science laboratories located in Cold Spring Harbor, New York on Long Island, USA. The Laboratory has research programs focusing on cancer, neurobiology, plant genetics, genomics and bioinformatics, and has a broad educational mission, including the recently... is the 120th day of the year (121st in leap years) in the Gregorian calendar. ... Year 2007 (MMVII) was a common year starting on Monday of the Gregorian calendar in the 21st century. ... The study of race and intelligence is the controversial study of how human intellectual capacities may vary among the different population groups commonly known as races. ... We dont have an article called Sunday Times Magazine Start this article Search for Sunday Times Magazine in. ...


Watson was quoted as saying he was "inherently gloomy about the prospect of Africa" as

all our social policies are based on the fact that their intelligence is the same as ours — whereas all the testing says not really.[46]

Hunt-Grubbe stated that Watson's "hope" was "everyone is equal" but quoted him as having said "people who have to deal with black employees find this not true." Furthermore, she suggested that Watson believed "you should not discriminate on the basis of colour" by quoting him as having said Affirmative action (US English), or positive discrimination (British English), is a policy or a program providing advantages for people of a minority group who are seen to have traditionally been discriminated against. ...

there are many people of colour who are very talented, but don’t promote them when they haven’t succeeded at the lower level.[46]

Watson was then attributed as having written

there is no firm reason to anticipate that the intellectual capacities of peoples geographically separated in their evolution should prove to have evolved identically. Our wanting to reserve equal powers of reason as some universal heritage of humanity will not be enough to make it so.[46]

The quotes attributed to him drew attention and criticism from press in several countries and was widely discussed on CNN[47], the BBC[48], several papers[49], peers[50] and by civil rights advocates.[51] The common perception was that of Watson claiming a link between race and intelligence with the BBC stating that "[Watson] claimed black people were less intelligent than white people".[48] In his book, the origin of the final written quote, Watson does not directly mention race as a factor in his hypothesized divergence of intellect between geographically isolated populations.[52] The study of race and intelligence is the controversial study of how human intellectual capacities may vary among the different population groups commonly known as races. ... For other uses, see BBC (disambiguation). ...


On October 18th, The London Science Museum canceled a talk that Watson was scheduled to give the following day,[48] stating that they believed Watson's comments had "gone beyond the point of acceptable debate." On the same day the Board of Trustees at Cold Spring Harbor Laboratory suspended Watson's administrative responsibilities, stating that

this action follows the Board’s public statement yesterday disagreeing with the comments attributed to Dr. Watson in the October 14, 2007 edition of The Sunday Times U.K.[53]

that they "vehemently disagree with...and are bewildered and saddened" by.[49]
Francis Collins, director of the National Human Genome Research Institute, a position inherited from Watson[50], said

I am deeply saddened by the events of the last week...in the aftermath of a racist statement...that was both profoundly offensive and utterly unsupported by scientific evidence.[49][50]

On October 19th, Watson issued an apology, stating that he was "mortified" and "cannot understand how I could have said what I am quoted as having said."[54][55] He also claimed to

understand why people, reading those words, have reacted in the ways they have ... To all those who have drawn the inference from my words that Africa, as a continent, is somehow genetically inferior, I can only apologize unreservedly. That is not what I meant. More importantly from my point of view, there is no scientific basis for such a belief.[56]

Saying he wanted to clarify his position, Watson said

... we do not yet adequately understand the way in which the different environments in the world have selected over time the genes which determine our capacity to do different things,...
... the overwhelming desire of society today is to assume that equal powers of reason are a universal heritage of humanity....
... it may well be. But simply wanting this to be the case is not enough. This is not science. To question this is not to give in to racism. This is not a discussion about superiority or inferiority, it is about seeking to understand differences, about why some of us are great musicians and others great engineers.[55][56]

Despite the apology and subsequent attempt to clarify his position the controversy continued. He returned to the US and Cold Harbor on the 19th October putting his further engagements in doubt. The University of Edinburgh's formally retracted an invitation to the "DNA, Dolly and Other Dangerous Ideas: The Destiny of 21st Century Science" Enlightenment Lecture on October 22nd.[57] The University of Edinburgh (Scottish Gaelic: ), founded in 1582,[4] is a renowned centre for teaching and research in Edinburgh, Scotland. ...


Watson resigned from Cold Spring Harbor Laboratory on October 25th.[58][47] Watson cited reasons for his retirement other than the controversy, though did refer to it.

Closer now to 80 than 79, the passing on of my remaining vestiges of leadership is more than overdue. The circumstances in which this transfer is occurring, however, are not those which I could ever have anticipated or desired.[59]

On December 9, 2007, a Sunday Times article[60] reported a claim by deCODE Genetics that 16% of Watson's DNA is of African origin and 9% is of Asian origin. deCODE's methods were not reported and details of the analysis were not published. According to deCODE's Kari Stefansson, the analysis relied on an error-ridden version of Watson's full genome sequence, and Stefansson "doubts [. . .] whether the 16 percent figure will hold up"[61] Making for a faulty jab at his ability to stand on a high horse of reason, ironically if this were a valid test his reasoning would only be strengthened The Sunday Times is the name of several Sunday newspapers. ...


Some believe that this might have been the true side of Mr. Watson, and that he had simply been waiting to publish such work until the end of his career. Mr. Watson has proven that our culture might not be quite ready for such discussion on this topic whether or not his scientific reasoning is justified.


Other statements

  • Watson has repeatedly supported genetic screening and genetic engineering in public lectures and interviews, arguing that stupidity is a disease and the "really stupid" bottom 10% of people should be cured.[62] He has also suggested that beauty could be genetically engineered, saying "People say it would be terrible if we made all girls pretty. I think it would be great."[62]
  • He has been quoted in The Sunday Telegraph as stating: "If you could find the gene which determines sexuality and a woman decides she doesn't want a homosexual child, well, let her."[63] The biologist Richard Dawkins wrote a letter to The Independent claiming that Watson's position was misrepresented by The Sunday Telegraph article, and that Watson would equally consider the possibility of having a heterosexual child to be just as valid as any other reason for abortion, to emphasise that Watson is in favor of allowing choice.[64]
  • On the issue of obesity, Watson has also been quoted as saying: "Whenever you interview fat people, you feel bad, because you know you're not going to hire them."[65]
  • Watson also had quite a few disagreements with Craig Venter regarding his use of EST fragments while Venter worked at NIH. Venter went on to found Celera genomics and continued his feud with Watson through the privately funded venture. Watson was even quoted as calling Venter "Hitler."[66]
  • While speaking at a conference in 2000, Watson had suggested a link between skin color and sex drive, hypothesizing that dark-skinned people have stronger libidos.[65][67] His lecture, complete with slides of bikini-clad women, argued that extracts of melanin — which give skin its color — had been found to boost subjects' sex drive. "That's why you have Latin lovers," he said, according to people who attended the lecture. "You've never heard of an English lover. Only an English patient."

Genetic testing allows the genetic diagnosis of vulnerabilities to inherited diseases, and can also be used to determine a persons ancestry. ... Elements of genetic engineering Genetic engineering, recombinant DNA technology, genetic modification/manipulation (GM) and gene splicing are terms that are applied to the direct manipulation of an organisms genes. ... This article deals with The Daily Telegraph in Britain, see The Daily Telegraph (Australia) for the Australian publication The Daily Telegraph is a British broadsheet newspaper founded in 1855. ... Clinton Richard Dawkins, FRS (born March 26, 1941) is a British ethologist, evolutionary biologist and popular science writer who holds the Charles Simonyi Chair for the Public Understanding of Science at the University of Oxford. ... Craig Venter, 2007 J. Craig Venter (born John Craig Venter October 14, 1946, Salt Lake City) is an American biologist and businessman. ... An expressed sequence tag or EST is a short sub-sequence of a transcribed spliced nucleotide sequence (either protein-coding or not). ... NIH can refer to: National Institutes of Health Norwegian School of Sports Sciences: (Norges idrettshøgskole - NIH) Not Invented Here This is a disambiguation page — a navigational aid which lists other pages that might otherwise share the same title. ... Celera Genomics was established in May 1998 by the Perkin-Elmer Corporation (now Applera Corporation), with Dr. J. Craig Venter from The Institute for Genomic Research (TIGR) as its first president. ... Hitler redirects here. ... For other uses, see Libido (disambiguation). ... Broadly, melanin is any of the polyacetylene, polyaniline, and polypyrrole blacks and browns or their mixed copolymers. ...

References

  1. ^ Watson is identified as an atheist by his acquaintance, Rabbi Marc Gellman. Trying to Understand Angry Atheists: Why do nonbelievers seem to be threatened by the idea of God?, by Rabbi Marc Gellman, Newsweek, 28 April 2006. Retrieved 11 November 2006.
  2. ^ When asked by a student if he believed in God, Watson replied "Oh, no. Absolutely not... The biggest advantage to believing in God is you don't have to understand anything, no physics, no biology. I wanted to understand." JoAnne Viviano. "Nobel Prize-winning scientist wows some, worries others", The Vindicator, 19 October 2007. Retrieved on 2007-10-19. 
  3. ^ a b The Nobel Prize in Physiology or Medicine 1962. Nobel Prize Site for Nobel Prize in Physiology or Medicine 1962.
  4. ^ James D. Watson (2007). "Avoid Boring People". Knopf. ISBN 0375412840. 
  5. ^ James Watson, The Nobel Prize in Physiology or Medicine 1962. NobelPrize.org (1964). Retrieved on 2007-12-12.
  6. ^ Watson retires. The Guardian (2007-10-25). Retrieved on 2007-12-12.
  7. ^ a b c d Anonymous (1999). Biography J.D. Watson, Nobel Lectures, Physiology or Medicine 1942-1962. Hackensack, NJ: World Scientific, 809-810. ISBN 9-810-23411-2.  Excerpt from nobelprize.org
  8. ^ Samuels, Rich. The Quiz Kids. Broadcasting in Chicago, 1921-1989. Retrieved on 2007-11-20.
  9. ^ a b Nobel laureate, Chicago native James Watson to receive University of Chicago. Alumni Medal June 2. The University of Chicago News Office (2007-06-01). Retrieved on 2007-11-20.
  10. ^ Friedberg, Errol C. (2005). The Writing Life of James D. Watson. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. ISBN 978-087969700-6.  Reviewed by Lewis Wolpert, Nature, (2005) 433:686-687.
  11. ^ a b c d e f "Chairman of the Bored", Steven Shapin, Harvard Magazine, January-February 2008
  12. ^ James D. Watson (biographical information). Cold Spring Harbor Laboratory. Retrieved on 2007-11-20.
  13. ^ Putnum, Frank W. (1994). Biographical Memoirs - Felix Haurowitz, volume 64, Washington, D.C.: The National Academies Press, 134-163. ISBN 0-309-06978-5. “Among [Haurowitz's] students was Jim Watson, then a graduate student of Luria.” 
  14. ^ Watson, J.D. 1950. The properties of x-ray inactivated bacteriophage. I. Inactivation by direct effect (.pdf). Journal of Bacteriology 60:697-718
  15. ^ a b c McElheny, Victor K. (2004). Watson and DNA: Making a Scientific Revolution. Basic Books, p. 28. ISBN 0-738-20866-3. 
  16. ^ Putmum, F.W. (1993). "Growing up in the golden age of protein science". Protein Science 2: pp. 1536-1542. 
  17. ^ Maaløe, O.; J.D. Watson (1951). "The transfer of radioactive phosphorus from parental to progeny phage". PNAS 37: pp. 507-513. PMID 16578386. 
  18. ^ Judson, H. F. (1979) The Eighth Day of Creation. Makers of the Revolution in Biology. New York: Simon and Schuster. ISBN 0-6712-2540-5. See chapter 2.
  19. ^ Most of the biographical account comes from Watson's 1968 autobiographical account, The Double Helix: A Personal Account of the Discovery of the Structure of DNA. The book was very controversial when it came out, though, as many of the participants still living disputed its account, especially of the role and personality of Franklin. In fact, the originally intended publisher, Harvard University Press, turned the manuscript down. For an edition which contains critical responses, book reviews, and copies of the original scientific papers, see James D. Watson, The Double Helix: A Personal Account of the Discovery of the Structure of DNA, Norton Critical Edition, Gunther Stent, ed. (New York: Norton, 1980).
  20. ^ a b Bragg's decision near the end of 1951 that Watson and Crick should not work on DNA structure is described on page 128 of The Eighth Day of Creation: Makers of the Revolution in Biology by Horace Freeland Judson published by Cold Spring Harbor Laboratory Press (1996) ISBN 0-87969-478-5. Bragg gave Watson permission to start DNA model work again in January 1953 (see page 162).
  21. ^ Watson, J.D. 1954. The structure of tobacco mosaic virus. I. X-ray evidence of a helical arrangement of sub-units around the longitudinal axis. Biochim Biophys Acta. 13:10-19. Entrez PubMed 13140277
  22. ^ a b Watson, J.D. and F.H. Crick. 1953. A structure for deoxyribose nucleic acids. Nature 171:737-738. doi:10.1038/171737a0
  23. ^ Judson, H.F.. "No Nobel Prize for Whining", New York Times, 2003-10-20. Retrieved on 2007-08-03. 
  24. ^ Watson, J.D. and G. Stent (preface). 1980. "The double helix : a personal account of the discovery of the structure of DNA." Norton: New York. ISBN 0-393-95075-1.
  25. ^ The NIH Almanac
  26. ^ Pollack, R.. 1994. Signs of Life: The Language and Meanings of DNA. Houghton Mifflin Company, p. 95. ISBN 0-395-73530-0.
  27. ^ Genome of DNA Discoverer Is Deciphered NYT, June 1, 2007.
  28. ^ Cold Spring Harbor Laboratory, June 28, 2003. Watson Genotype Viewer Now On Line. Press release. Retrieved on September 16, 2007.
  29. ^ The Lasker Foundation.[1]. Retrieved on November 4, 2007.
  30. ^ American Philosophical Society.[2]. Retrieved on November 4, 2007.
  31. ^ National Constitution Center.[3]. Retrieved on November 4, 2007.
  32. ^ The National Science Foundation.[4]. February 14, 2006. Retrieved on November 4, 2007.
  33. ^ The Nobel Foundation, 1962.[5]. Retrieved on November 4, 2007.
  34. ^ a b The Official Site of the Presidential Medal of Freedom, 2007.[6]. Retrieved on November 4, 2007.
  35. ^ "["Dr. James D. Watson Retires as Chancellor of Cold Spring Harbor Laboratory", CSHL, October 25, 2007. Retrieved on November 4, 2007.
  36. ^ Controversial DNA Scientist James Watson Retires http://www.sci-tech-today.com/story.xhtml?story_id=030001P1XOL0 © 2007 Associated Press/AP Online. © 2007 Sci-Tech Today. October 25, 2007 11:29AM
  37. ^ Teresa Firmino. "Nobel James Watson vai presidir ao conselho científico da Fundação Champalimaud", Público, 2007-03-20. Retrieved on 2007-03-22. (Portuguese) 
  38. ^ Allen Institute for Brain Science Web page
  39. ^ "Faculty Support Grows For Anti-War Proposal", The Harvard Crimson, October 3, 1969. November 4, 2007.
  40. ^ "Three Harvard Scientists Lead Call to Stop Nuclear Reactors", The Harvard Crimson, August 5, 1975. November 4, 2007.
  41. ^ Maddox, B. 2003. Rosalind Franklin: The Dark Lady of DNA. Harper Perennial. ISBN 0-060-98508-9.
  42. ^ Elkin, L.O. 2003. "Rosalind Franklin and the Double Helix". Physics Today 56(3):42.
  43. ^ Wilkins, M.H.F., Stokes A.R. and H.R. Wilson. Molecular Structure of Deoxypentose Nucleic Acids. Nature 171:738-740 doi:10.1038/171738a0
  44. ^ Franklin R. and R.G. Gosling. 1953. Molecular Configuration in Sodium Thymonucleate. Nature 171:740-741 doi:10.1038/171740a0
  45. ^ Statutes of the Nobel Foundation, § 4
  46. ^ a b c d e Hunt-Grubbe, C. "The elementary DNA of dear Dr. Watson", Times Online, October 14, 2007. Retrieved October 24, 2007.
  47. ^ a b ""Nobel prize-winning biologist resigns."", CNN, October 25, 2007. Retrieved on October 25, 2007.
  48. ^ a b c "Museum drops race row scientist", BBC, October 18, 2007. Retrieved October 24, 2007.
  49. ^ a b c Wigglesworth, K.DNA pioneer quits after race comments, L.A. Times, October 26th, 2007. Retrieved December 5th, 2007
  50. ^ a b c Malloy, J. James Watson tells the inconvenient truth: Faces the consequences, Gene Expression, October 31st, 2007. Retried December 5th, 2007
  51. ^ Race remarks get Nobel winner in trouble, MSNBC and AP, October 18, 2007. Retrieved October 18, 2007.
  52. ^ Watson, James (September/October 2007). "Blinded by Science. An exclusive excerpt from Watson's new memoir, Avoid Boring People: Lessons from a Life in Science.". 02138 Magazine: p. 102. Retrieved on 2007-11-28. “As we find the human genes whose malfunctioning gives rise to such devastating developmental failures, we may well discover that sequence differences within many of them also lead to much of the observable variation in human IQs. A priori, there is no firm reason to anticipate that the intellectual capacities of peoples geographically separated in their evolution should prove to have evolved identically. Our desire to reserve equal powers of reason as some universal heritage of humanity will not be enough to make it so.” 
  53. ^ Cold Springs Harbor Laboratory. October 18, 2007. Statement by Cold Spring Harbor Laboratory Board of Trustees and President Bruce Stillman, Ph.D. Regarding Dr. Watson’s Comments in The Sunday Times on October 14, 2007. Press release. Retrieved October 24, 2007.
  54. ^ van Marsh, A. "Nobel-winning biologist apologizes for remarks about blacks", CNN, October 19, 2007. Retrieved October 24, 2007.
  55. ^ a b Watson, J.D. "James Watson: To question genetic intelligence is not racism", Independent, October 19, 2007. Retrieved October 24, 2007
  56. ^ a b Syal, R. "Nobel scientist who sparked race row says sorry - I didn't mean it", Times Online, October 19, 2007. Retrieved October 24, 2007.
  57. ^ ""Watson Returns to USA after race row"", International Herald Tribune, October 19, 2007. Retrieved on November 10, 2007
  58. ^ http://www.technewsworld.com/story/60001.html DNA Pioneer Watson Resigns Amid Cloud of Scandal By Malcolm Ritter AP 10/25/07 11:29 AM PT
  59. ^ Watson, J.Statement by James D. Watson "Retirement", "N Y Times", 25th October, 2007. Retrieved 5th December, 2007.
  60. ^ Jonathan Leake DNA pioneer James Watson is blacker than he thought, "Sunday Times", 9 December, 2007. Retrieved 9 December, 2007.
  61. ^ Chris Wilson What does it mean to say James Watson is 16 percent African?, "Slate", 14 December, 2007. Retrieved 29 February, 2008.
  62. ^ a b Bhattacharya, S. "Stupidity should be cured, says DNA discoverer", New Scientist News Service, February 28, 2003. Retrieved June 24, 2007.
  63. ^ Macdonald, V. "Abort babies with gay genes, says Nobel winner", The Telegraph, February 16, 1997. Retrieved on October 24, 2007.
  64. ^ Dawkins, R. "Letter: Women to decide on gay abortion", The Independent via findarticles.com, February 19, 2007. Retrieved October 24, 2007.
  65. ^ a b Abate, T. "Nobel Winner's Theories Raise Uproar in Berkeley Geneticist's views strike many as racist, sexist", San Francisco Chronicle, November 13, 2000. Retrieved on October 24, 2007.
  66. ^ Shreeve. J. 2005. The Genome War: How Craig Venter Tried to Capture the Code of Life and Save the World. Ballantine Books, p. 48. ISBN 0-345-43374-2.
  67. ^ Thompson C. and A. Berger. 2000. Agent provocateur pursues happiness. British Medical Journal 321:12.

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Further reading

  • Chadarevian, S. (2002) Designs For Life: Molecular Biology After World War II. Cambridge University Press ISBN 0-521-57078-6
  • Chargaff, E. (1978) Heraclitean Fire. New York: Rockefeller Press.
  • Chomet, S., ed., (1994) D.N.A.: Genesis of a Discovery London: Newman-Hemisphere Press.
  • Crick, F.H.C. (1988) What Mad Pursuit: A Personal View of Scientific Discovery (Basic Books reprint edition, 1990) ISBN 0-465-09138-5
  • Friedburg, E. C. 2005) "The Writing Life of James D. Watson". "Cold Spring Harbor Laboratory Press" ISBN 0879697008
  • Hunter, G. (2004) Light Is A Messenger: the life and science of William Lawrence Bragg. Oxford University Press. ISBN 0-19-852921-X
  • Inglis, J., Sambrook, J. & Witkowski, J. A. (eds.) Inspiring Science: Jim Watson and the Age of DNA. Cold Spring Harbor Laboratory Press. 2003. ISBN 978-087969698-6.
  • Judson, H. F. (1996). The Eighth Day of Creation: Makers of the Revolution in Biology, Expanded edition. Cold Spring Harbor Laboratory Press. ISBN 0879694785
  • Maddox, B. (2003). Rosalind Franklin: The Dark Lady of DNA. Harper Perennial. ISBN 0060985089
  • Robert Olby; 1974) The Path to The Double Helix: Discovery of DNA. London: MacMillan. ISBN 0-486-68117-3; Definitive DNA textbook, with foreword by Francis Crick, revised in 1994 with a 9 page postscript.
  • Robert Olby; (2003) "Quiet debut for the double helix" Nature 421 (January 23): 402-405.
  • Robert Olby; "Francis Crick: A Biography", Cold Spring Harbor Laboratory Press, ISBN 9780879697983, to be published in late 2008.
  • Ridley, M. (2006) Francis Crick: Discoverer of the Genetic Code (Eminent Lives) New York: Harper Collins. ISBN 0-06-082333-X.
  • Watson, J. D. (1968) The Double Helix: A Personal Account of the Discovery of the Structure of DNA. New York: Atheneum.
  • Watson, J. D. (1968). The Double Helix: A Personal Account of the Discovery of the Structure of DNA. (Norton Critical Editions, 1981). Edited by Gunther S. Stent. W. W. Norton & Company. ISBN 0-393-95075-1
  • Watson, J. D., T. A. Baker, S. P. Bell, A. Gann, M. Levine, and R. Losick, eds., (2003) Molecular Biology of the Gene. (5th edition) New York: Benjamin Cummings ISBN 0-8053-4635-X
  • Watson, J. D. (2002) Genes, Girls, and Gamow: After the Double Helix. New York: Random House. ISBN 0-375-41283-2
  • Watson, J. D. with A. Berry (2003) DNA: The Secret of Life New York: Random House. ISBN 0-375-41546-7
  • Watson, J.D. (2007) Avoid Boring People and Other Lessons from a Life in Science, New York, Random House, ISBN 978-0-375-41284-4, 366 pp.
  • Wilkins, M. (2003) The Third Man of the Double Helix: The Autobiography of Maurice Wilkins. Oxford: Oxford University Press. ISBN 0-19-860665-6.
  • The History of the University of Cambridge: Volume 4 (1870 to 1990), Cambridge University Press, 1992.

// Erwin Chargaff (Czernowitz, August 11, 1905 – New York City, USA, June 20, 2002) was an Austrian biochemist who emigrated to the United States during the Nazi era. ... Robert Olby is a professor in the Department of History and Philosophy of Science at the University of Pittsburgh. ... Robert Olby is a professor in the Department of History and Philosophy of Science at the University of Pittsburgh. ... Robert Olby is a professor in the Department of History and Philosophy of Science at the University of Pittsburgh. ... Matthew (Matt) Ridley (born February 7, 1958 at Newcastle upon Tyne) (not to be confused with Mark Ridley) is an English science writer. ... James Watson The Double Helix: A Personal Account of the Discovery of the Structure of DNA is an autobiographical account of the discovery of structure of DNA. It was written by James D. Watson and published in 1968. ... Maurice Hugh Frederick Wilkins CBE FRS (15 December 1916 – 5 October 2004) was a New Zealand-born British molecular biologist, and Nobel Laureate who contributed research in the fields of phosphorescence, radar, isotope separation, and X-ray diffraction. ...

Multimedia

  • BBC Four Interviews - Watson and Crick speaking on the BBC in 1962, 1972, and 1974.
  • Charlie Rose "DNA: The Secret of Life" - video interview with James D. Watson.
  • Charlie Rose "Charles Darwin" - Charlie Rose interviews Watson and Edward O. Wilson on biology, and the importance of Darwin.
  • NPR Science Friday: "A Conversation with Genetics Pioneer James Watson" - Ira Flatow interviews Watson on the history of DNA and his recent book A Passion for DNA: Genes, Genomes, and Society.
  • NPR Science Friday "DNA: The Secret of Life" - Ira Flatow interviews Watson on his new book.
  • On Point "James Watson on how to climb the slippery double helix of life" - Tom Ashbrook talks to James Watson about his new memoir, "Avoid Boring People: Lessons from a Life in Science."

E.O. Wilson with Dynastes hercules E. O. Wilson, or Edward Osborne Wilson, (born June 10, 1929) is an entomologist and biologist known for his work on ecology, evolution, and sociobiology. ... For other people of the same surname, and places and things named after Charles Darwin, see Darwin. ...

External links

  • James Watson's Personal Genome Sequence
  • Watson's personal DNA sequence archive at the National Institutes of Health
  • Double Helix: 50 Years of DNA - Nature celebrates the 50th anniversary.
  • "The complex James Watson": an article in the TLS by Jerry A. Coyne, December 12 2007
  • DNA Interactive - This site from the Dolan DNA Learning Center commemorates the discovery of the structure of DNA and includes dozens of animations, as well as interviews with James Watson and others.
  • DNA from the Beginning - another DNA Learning Center site on the basics of DNA, genes, and heredity, from Mendel to the human genome project.
  • Presentation speech at the Nobel Prize ceremony in 1962
  • Nobel Foundation biography
    • DNA - The Double Helix
  • Cold Spring Harbor Laboratory biography
  • MSN Encarta biography
  • The King's College London team
  • Discover "Reversing Bad Truths" - David Duncan interviews Watson.
  • Remembering Francis Crick - with first press stories on DNA.
  • The New York Times story - facsimile reproduction of the original text in June 1953.
  • The New York Times 50th anniversary series of articles
  • Linus Pauling and the Race for DNA - quotes from Robert Olby on who may have discovered the structure of DNA.
  • Base pairing in DNA Double Helix - shows the hydrogen bonds
  • TED Talk- James Watson on how he discovered DNA, a TED Talk
  • Controversial interview October 14, 2007. The Sunday Times
Persondata
NAME Watson, James Dewey
ALTERNATIVE NAMES
SHORT DESCRIPTION molecular biologist,
DATE OF BIRTH 1928-04-06
PLACE OF BIRTH Chicago, Illinois, U.S.
DATE OF DEATH
PLACE OF DEATH
Molecular biology is the study of biology at a molecular level. ... For other uses, see Chicago (disambiguation). ... This article is about the U.S. State. ... For other uses of terms redirecting here, see US (disambiguation), USA (disambiguation), and United States (disambiguation) Motto In God We Trust(since 1956) (From Many, One; Latin, traditional) Anthem The Star-Spangled Banner Capital Washington, D.C. Largest city New York City National language English (de facto)1 Demonym American...

 
 

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