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Encyclopedia > Interleukin 5

IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. Interleukins are a group of cytokines that are expressed by white blood cells (leukocytes, hence the -leukin) as a means of communication (inter-). The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune... A T helper cell (or TH cell), is a T cell (a type of white blood cell or leukocyte) that only plays a role in the adaptive immune system. ... A mast cell (or mastocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. ... B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response). ... Schematic of antibody binding to an antigen An antibody is a protein complex used by the immune system to identify and neutralize foreign objects like bacteria and viruses. ...


Reference

Coico, R., Sunshine, G., and Benjamin, E. (2003). “Immunology: A Short Course.” Pg. 151-153.

Interleukins edit

IL-1 | IL-2 | IL-3 | IL-4 | IL-5 | IL-6 | IL-7 | IL-8 | IL-9 | IL-10 | IL-11 | IL-12 | IL-13 | IL-14 | IL-15 | IL-16 | IL-17 | IL-18 | IL-19 | IL-20 | IL-21 | IL-22 | IL-23 | IL-24 | IL-25 Interleukins are a group of cytokines that are expressed by white blood cells (leukocytes, hence the -leukin) as a means of communication (inter-). The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune... Interleukin-1 (IL-1) is secreted by the macrophages, monocytes and dendritic cells. ... Interleukin-2 (IL-2) is an interleukin, a type of biological response modifier, a substance that can improve the bodys natural response to disease. ... Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the bodys natural response to disease as part of the immune system. ... Interleukin-4, abreviated IL-4, is a lymphokine that stimulates the proliferation of activated B-cells and T-cells, among other effects. ... Interleukin-6 (IL-6) is a pro-inflammatory cytokine secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. ... Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. ... Interleukin 9 (IL-9) is a cytokine produced by T-cells and specifically by CD4+ helper cells. ... Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine, capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFα and GM-CSF by cells such as macrophages and Th1 cells. ... Interleukin 12 (IL-12) is an interleukin that are naturally produced by macrophages and human B-lymphoblastoid cells (NC-37)in response to antigenic stimulation. ... Stimulates growth and differentiation of B-Cells, inhibits Th1 cells and the production of macrophage inflamatory cytokines, stimulates class switching to IgG1 and IgE. Categories: | | | ...

Interleukins, generally speaking make things more attractive to other immune cells. They are collectively termed cytokines and are found in a variety of different families


  Results from FactBites:
 
interleukins - multiple sclerosis encyclopaedia (393 words)
Interleukins (also called lymphokines) are a sub-group of small soluable proteins called cytokines which function as chemical messengers between cells.
The role of interleukins is to mediate and control the immunologic and inflamatory response.
Interleukins are largely secreted by white blood cells (leukocytes) and received by receptors in others.
IL5 - interleukin 5 (colony-stimulating factor, eosinophil) (4975 words)
Interleukin 5 (IL-5) has an enhancing effect on IL-4 induced immunoglobulin E (IgE) synthesis.
Soluble interleukin 5 (IL-5), but no interleukin 3 (IL-3) and granulocyte-macrophage colony- stimulating factor (GM-CSF), was detected in sera from all patients.
Interleukin 4 (IL 4)- induced IgE production by peripheral blood lymphocytes and tonsil cells from normal donors was enhanced in a dose-dependent fashion by IL 5.
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