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Encyclopedia > Hypogonadism
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MedlinePlus Medical Encyclopedia: Hypogonadism (783 words)
The cause of hypogonadism may be "primary" or "central." In primary hypogonadism, the ovaries or testes themselves do not function properly.
The most common genetic disorders that cause primary hypogonadism are Turner syndrome (in women) and Klinefelter syndrome (in men).
A genetic cause of central hypogonadism that also produces an inability to smell is Kallmann syndrome (males).
Prevalence, Diagnosis and Treatment of Hypogonadism in Primary Care Practice (1755 words)
Hypogonadism is defined as deficient or absent male gonadal function that results in insufficient testosterone secretion.
Hypogonadism may be primary due to testicular failure, or secondary due to hypothalamic-pituitary axis dysfunction, resulting in the production or release of insufficient testosterone to maintain testosterone-dependent functions and systems.
Hypogonadism affects an estimated 4 to 5 million men in the United States, and although it may occur in men at any age, low testosterone levels are especially common in older males.
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