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Encyclopedia > Hydrolases
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Hydrolase - Wikipedia, the free encyclopedia (153 words)
In biochemistry, a hydrolase is an enzyme that catalyzes the hydrolysis of a chemical bond.
Systematic names of hydrolases are formed as "substrate hydrolase." However, common names are common, using only "substratease." For example, a nuclease is a hydrolase that cleaves nucleic acids.
Hydrolases are classified as EC 3 in the EC number classification of enzymes.
FAAH - Fatty-acid amide hydrolase (5532 words)
The enzyme fatty acid amide hydrolase (FAAH) catalyses hydrolysis of oleamide, a sleep-inducing lipid whose concentration in the cerebrospinal fluid (CSF) is elevated in sleep-deprived mammals.
The distribution in the rat brain of fatty acid amide hydrolase (FAAH) an enzyme that catalyzes the hydrolysis of the endogenous cannabinoid anandamide was studied by immunohistochemistry.
Moreover, we observed a decreased activity of the anandamide membrane transporter (AMT) and of the anandamide hydrolase [ fatty acid amide hydrolase (FAAH)], whereas the binding of anandamide to cannabinoid receptors was unaffected.
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