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Encyclopedia > Hassall's corpuscles
Hassall's corpuscles
Minute structure of thymus. Follicle of injected thymus from calf, four days old, slightly diagrammatic, magnified about 50 diameters. The large vessels are disposed in two rings, one of which surrounds the follicle, the other lies just within the margin of the medulla.

A and B. From thymus of camel, examined without addition of any reagent. Magnified about 400 diameters.
A. Large colorless cell, containing small oval masses of hemoglobin. Similar cells are found in the lymph glands, spleen, and medulla of bone.
B. Colored blood corpuscles.
Gray's subject #274 1274
Dorlands/Elsevier c_56/12261097

Hassall's corpuscles (or thymic corpuscles) are structures in the thymus gland, composed of epithelial reticular cells. In human anatomy, the thymus is an organ located in the upper anterior portion of the chest cavity. ... Cattle calf A Calf (plural calves) is the young of an animal. ... Medulla in general means the inner part, and derives from the Latin word for marrow. In medicine it is contrasted to the cortex. ... Species Camelus bactrianus Camelus dromedarius Camels are even-toed ungulates in the genus Camelus. ... 3-dimensional structure of hemoglobin. ... Elseviers logo Elsevier, the worlds largest publisher of medical and scientific literature, forms part of the Reed Elsevier group. ... Thymus, see Thyme. ... In zootomy, epithelium is a tissue composed of a layer of cells. ...

They are named for Arthur Hill Hassall, who discovered them in 1849.

They function in dendritic cells signaling.[1][2] Dendritic cells (DC) are immune cells and form part of the mammal immune system. ...


  1. ^ * Watanabe N, Wang Y, Lee H, Ito T, Wang Y, Cao W, Liu Y (2005). "Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus.". Nature 436 (7054): 1181-5. PMID 16121185.
  2. ^ "Old mystery solved, revealing origin of regulatory T cells that 'police' and protect the body"

Dendritic cells (DC) are immune cells and form part of the mammal immune system. ... CD4 (cluster of differentiation 4) is a molecule that is expressed on the surface of T helper cells (as well as regulatory T cells and dendritic cells). ... T cells are a subset of lymphocytes that play a large role in the immune response. ...

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Lymphatic system
Bone marrow | Thymus (Hassall's corpuscles) | Spleen (White pulp, Periarteriolar lymphoid sheaths, Marginal zone, Red pulp) | Tonsils (Palatine, Lingual, Adenoid)

Mucosa-associated lymphoid tissue: Gut-associated lymphoid tissue | Peyer's patches Who Named It is a Norwegian database of several thousand eponymous medical signs and the doctors associated with their identification. ... The College of Medicine at Urbana-Champaign is a graduate school at the University of Illinois at Urbana-Champaign. ... The University of Kansas (often referred to as KU or Kansas) is an institution of higher learning located in Lawrence, Kansas. ... The University of Southern California (commonly referred to as USC, SC, Southern California, and Southern Cal[1]), located in the downtown district of Los Angeles, California, USA, was founded in 1880, making it Californias oldest private research university. ... The University of Oklahoma, often called OU or Oklahoma, is a coeducational public research university located in the U.S. state of Oklahoma. ... For the unrelated Jesuit university in Chestnut Hill, see Boston College. ... The human lymphatic system The lymphatic system is a complex network of lymphoid organs, lymph nodes, lymph ducts, and lymph vessels that produce and transport lymph fluid from tissues to the circulatory system. ... Grays Anatomy illustration of cells in bone marrow. ... In human anatomy, the thymus is an organ located in the upper anterior portion of the chest cavity. ... The spleen is a ductless, vertebrate gland that is closely associated with the circulatory system, where it functions in the destruction of old red blood cells in holding a reservoir of blood. ... The marginal zone is a portion of the spleen. ... The Palatine tonsils with the soft palate, uvula, and tongue visible. ... Most commonly, the term tonsils refers to the palatine tonsils that can be seen in the back of the throat. ... The lingual tonsils are rounded masses of lymphatic tissue that cover the posterior region of the tongue. ... Adenoids, or pharyngeal tonsils, are folds of lymphatic tissue covered by ciliated epithelium. ... The mucosa-associated lymphoid tissue (MALT) is the diffuse system of small concentrations of lymphoid tissue found in various sites of the body such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin. ... Overview About 70% of the bodys immune system is found in the digestive tract. ... Peyers patches are secondary lymphoid organs named after the 17th-century Swiss anatomist Hans Conrad Peyer. ...

Lymph nodes: Cervical lymph nodes | Common iliac lymph nodes Deep inguinal lymph nodes | External iliac lymph nodes | Inferior mesenteric lymph nodes | Internal iliac lymph nodes | Lateral aortic lymph nodes | Paraaortic lymph node | Preaortic lymph nodes | Paratracheal chain | Retroaortic lymph nodes | Sentinel lymph node | Superficial inguinal lymph nodes | Virchow's node Structure of the lymph node. ... Cervical lymph nodes are lymph nodes found in the neck. ... The common iliac lymph nodes, four to six in number, are grouped behind and on the sides of the common iliac artery, one or two being placed below the bifurcation of the aorta, in front of the fifth lumbar vertebra. ... The deep inguinal lymph nodes are located medial to the femoral vein and under the cribriform fascia. ... The external iliac lymph nodes, from eight to ten in number, lie along the external iliac vessels. ... The internal iliac lymph nodes (or hypogastric) surround the hypogastric vessels, and receive the lymphatics corresponding to the distribution of the branches of the hypogastric artery, i. ... The paraaortic lymph nodes (also para-aortic, periaortic, and peri-aortic) are a group of lymph nodes that lie in front of the lumbar vertebral bodies near the aorta. ... The sentinel lymph node is the hypothetical first lymph node reached by metastasizing cancer cells from a tumor. ... The superficial inguinal lymph nodes form a chain immediately below the inguinal ligament. ... In medicine (oncology), Virchows node is an enlarged, hard, left supraclavicular lymph node which can contain metastasis of visceral malignancy. ...

Lymph vessels: Thoracic duct | Right lymphatic duct | Cisterna chyli  | Lumbar trunk | Intestinal trunk In anatomy, lymph vessels are thin walled, valved structures that carry lymph away from the tissues, through the lymph nodes and thoracic duct back to the general circulation. ... In human anatomy, the thoracic duct is an important part of the lymphatic system — it is the largest lymphatic vessel in the body. ... The cisterna chyli (or receptaculum chyli) is a dilated sac at the lower end of the thoracic duct into which the intestinal trunk and two lumbar lymphatic trunks flow. ...

Lymph | Lymphocytes | Immune system In mammals including humans, the lymphatic vessels (or lymphatics) are a network of thin tubes that branch, like blood vessels, into tissues throughout the body. ... A lymphocyte is a type of white blood cell involved in the human bodys immune system. ... ...



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