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Encyclopedia > Growth factors

Growth factor is any of about twenty small proteins that attach to specific receptors on the surface of stem cells in bone marrow and promote differentiation and maturation of these cells into morphotic constituents of blood.


The most important growth factors are :

For the last two decades growth factors have been increasingly used in treatment of hematologic and oncologic diseases like :


  Results from FactBites:
 
ScienceDaily: Growth Factor Stimulates Rapid Extension Of Key Motor Neurons In Brain (746 words)
Science Daily — A growth factor known to be important for the survival of many types of cells stimulates rapid extension of corticospinal motor neurons -- critical brain cells that connect the cerebral cortex with the spinal cord and that die in motor neuron diseases like amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).
In order to study growth factor controls over these cells, Macklis and Hande Ozdinler, PhD, a postdoctoral fellow in his laboratory, developed a new way of isolating pure populations of CSMN in culture and found that IGF-1 was a prime candidate for control over CSMN development.
Studies suggest that psoriatic arthritis is caused by genetic, immunological and environmental factors.
Growth factor - Wikipedia, the free encyclopedia (618 words)
Growth factor is a protein that acts as a signaling molecule between cells (like cytokines and hormones) that attaches to specific receptors on the surface of a target cell and promotes differentiation and maturation of these cells.
The term growth factor is sometimes used interchangeably among scientitsts with the term cytokine.
Growth factor signifies a positive effect on cell growth and cellular differentiation, but cytokine is a neutral term in regards to what it is being signalled.
  More results at FactBites »

 
 

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