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Encyclopedia > Granulocytes

Granulocytes are a category of white blood cells, characterised by the fact that all types have differently staining granules in their cytoplasm on light microscopy. They are also being referred to as polymorphnuclear leukocytes (PMN or PML), because of the varying shapes of the nucleus, which is usually lobed into three segments.

The most abundant granulocyte is the neutrophil (neutrally staining granules). Often, the words "granulocyte" and "neutrophil", as well as other related terms (such as granulocytosis), are used interchangeably.

The granulocytes are:

See also: white blood cell, blood count

Cardiovascular system - Blood
Red blood cells - White blood cells - Platelets - Blood plasma
White blood cells
Granulocytes (Neutrophil granulocytes, Eosinophil granulocytes, Basophil granulocytes) - Lymphocytes - Monocytes
Coagulation factors: - Fibrin - Thrombin - FVII - FVIII - FIX - FXII - FXIII - HMWK - vWF
Inhibitors: Antithrombin - Protein C - Protein S - TFPI
Fibrinolysis: Plasmin - tPA/uPA - PAI-1/2 - α2-AP

  Results from FactBites:
Publications - Granulocyte Transfusions (1550 words)
Granulocyte function is normal or near normal.6 Granulocyte recovery and survival are adversely affected by as little as 8-24 hours storage.
Based on these trials, granulocyte transfusion can be considered for severely neutropenic patients with documented bacterial infection who have failed 24-48 hours of appropriate antibiotic therapy to which bacteria are susceptible.
Granulocytes obtained from these donors are functionally normal and may have improved phagocytic, bactericidal, and fungicidal activity.
  More results at FactBites »



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