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Encyclopedia > Granulocyte
Eosinophil granulocyte
Eosinophil granulocyte
Basophil granulocyte
Basophil granulocyte

Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm.[1] They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes,[2] the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins. Image File history File links PBEosinophil. ... Image File history File links PBBasophil. ... A scanning electron microscope image of normal circulating human blood. ... A granule is a small grain. ... It has been suggested that Cytoplast be merged into this article or section. ... HeLa cells stained for DNA with the Blue Hoechst dye. ... This article does not cite any references or sources. ... A complement protein attacking an invader. ...

Contents

Classification

There are three types of granulocytes, distinguished by their appearance under Wright's stain: Wrights stain is a technique in histology that is used to make the differences between cells visible under light microscopy. ...

Their names are derived from their staining characteristics; for example, the most abundant granulocyte is the neutrophil granulocyte, which has neutrally-staining cytoplasmic granules. This article does not cite any references or sources. ... Image of an eosinophil Eosinophil granulocytes, commonly referred to as eosinophils (or less commonly as acidophils), are white blood cells of the immune system that are responsible for combating infection by parasites in vertebrates. ... This article or section does not cite its references or sources. ... Staining is a biochemical technique of adding a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound. ... This article does not cite any references or sources. ... It has been suggested that Cytoplast be merged into this article or section. ...


Other white blood cells which are not granulocytes ("agranulocytes") are mainly lymphocytes and monocytes. Agranulocytes are a category of white blood cells characterised by the absence of granules in their cytoplasm. ... A scanning electron microscope (SEM) image of a single human lymphocyte. ... Monocyte A monocyte is a leukocyte, part of the human bodys immune system that protect against blood-borne pathogens and move quickly to sites of infection in the tissues. ...


Toxic materials produced or released

Examples of toxic materials produced or released by degranulation by granulocytes on the ingestion of microorganism includes: The degranulation process in a Mast cell. ...

This article or section is in need of attention from an expert on the subject. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ... Lewis electron configuration of superoxide. ... Hydrogen peroxide (H2O2) is a very pale blue liquid which appears colourless in a dilute solution, slightly more viscous than water. ... This prefix in chemical nomenclature indicates the presence of a hydroxyl functional group (-OH). ... The hypochlorite ion The hypochlorite ion is ClO−. A hypochlorite compound is a chemical compound containing this group, with chlorine in oxidation state +1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Standard atomic weight 14. ... R-phrases , , , , S-phrases , , , Supplementary data page Structure and properties n, εr, etc. ... An antimicrobial is a substance that kills or slows the growth of microbes like bacteria (antibacterial activity), fungi (antifungal activity), viruses (antiviral activity), or parasites (antiparasitic activity). ... Defensins are small (30-35 residue) cysteine rich cationic proteins found in vertebrate phagocytes (notably the azurophil granules of neutrophils) and active against bacteria, fungi and enveloped viruses. ... In chemistry, a cationic species is one that contains a full positive charge. ... Neuraminidase ribbon diagram An enzyme (in Greek en = in and zyme = blend) is a protein, or protein complex, that catalyzes a chemical reaction and also controls the 3D orientation of the catalyzed substrates. ... Lysozyme single crystal. ... Gram-positive bacteria are those that are stained dark blue or violet by gram staining, in contrast to gram-negative bacteria, which are not affected by the stain. ... An acid hydrolase (lysosomal acid lipase) is an enzyme that works best at acidic pHs. ...

Pathology

Granulocytopenia is an abnormally low concentration of granulocytes in the blood. This condition reduces the body's resistance to many infections. Closely-related terms include agranulocytosis and neutropenia. Neutropenia (or neutropaenia, adjective neutrop(a)enic) is a hematological disorder characterized by an abnormally low number of neutrophil granulocytes (a type of white blood cell). ...


A granuloma is a tumor containing granulocytes, and a "granulomatosis" is a necrotizing granuloma. H&E section of non-caseasting granuloma seen in the colon of a patient with Crohns disease In medicine (anatomical pathology), a granuloma is a group of epithelioid macrophages surrounded by a lymphocyte cuff. ... Tumor or tumour literally means swelling, and is sometimes still used with that meaning. ... Necrosis (in Greek Νεκρός = Dead) is the name given to unprogrammed death of cells/living tissue (compare with apoptosis - programmed cell death). ...


There is usually a granulocyte chemotactic defect in individuals who suffer from insulin dependent diabetes mellitus. Chemotaxis is a kind of taxis, in which bodily cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment. ... Diabetes mellitus type 1 (Type 1 diabetes, Type I diabetes, T1D, IDDM) is a form of diabetes mellitus. ...


Additional images

See also

A full blood count (FBC) or complete blood count (CBC) is a test requested by a doctor or other medical professional that gives information about the cells in a patients blood. ... A scanning electron microscope image of normal circulating human blood. ...

References

  1. ^ granulocyte at eMedicine Dictionary
  2. ^ polymorphonuclear+leukocyte at eMedicine Dictionary

eMedicine is an online clinical medical knowledge base that was founded in 1996. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ...

External links


  Results from FactBites:
 
Publications - Granulocyte Transfusions (1550 words)
Granulocyte function is normal or near normal.6 Granulocyte recovery and survival are adversely affected by as little as 8-24 hours storage.
Based on these trials, granulocyte transfusion can be considered for severely neutropenic patients with documented bacterial infection who have failed 24-48 hours of appropriate antibiotic therapy to which bacteria are susceptible.
Granulocytes obtained from these donors are functionally normal and may have improved phagocytic, bactericidal, and fungicidal activity.
  More results at FactBites »

 
 

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