In boys, testicular enlargement is the first physical sign of gonadarche, and usually of puberty.
In girls, ovarian growth cannot be directly seen, so thelarche and growth acceleration are usually the first evidence of gonadarche.
Gonadarche should be contrasted with adrenarche. Gonadarche indicates that true central puberty has begun, while adrenarche is an independent maturational process only loosely associated with complete puberty.
Categories: Developmental biology | Sexology | Pediatric medicine
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