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Encyclopedia > Glycolipid

Glycolipids are carbohydrate-attached lipids. Their role is to provide energy and also serve as markers for cellular recognition. Carbohydrates are chemical compounds that contain oxygen, hydrogen, and carbon atoms. ... Figure 1: Basic lipid structure. ... A genetic marker is a specific discovered single nucleotide polymorphism or SNP (or simply mutation) of certain section of DNA of a specific genome. ... Cellular redirects here. ...


They occur where a carbohydrate chain is associated with phospholipids in the cell surface membrane. The carbohydrates are found on the outer surface of all eukaryotic cell membranes. Carbohydrates are chemical compounds that contain oxygen, hydrogen, and carbon atoms. ... Two schematic representations of a phospholipid. ... Cells in culture, stained for keratin (red) and DNA (green) The cell is the structural and functional unit of all living organisms, and are sometimes called the building blocks of life. ... A biological membrane or biomembrane is a membrane which acts as a barrier within or around a cell. ... Kingdoms Eukaryotes are organisms with complex cells, in which the genetic material is organized into membrane-bound nuclei. ...


They extend from the phospholipid bilayer into the aqueous environment outside the cell where it acts as a recognition site for specific chemicals as well as helping to maintain the stability of the membrane and attaching cells to one another to form tissues. Biological tissue is a substance made up of cells that perform a similar function. ...


Glycosphingolipids, which are found in whole milk, fight gastrointestinal infections.


Types of glycolipids

Following is an incomplete listing of glycolipid types.


  Results from FactBites:
 
Boehringer Ingelheim News - Heinrich Wieland Prize 2006 awarded for excellence in glycolipid chemistry (419 words)
Ingelheim and Munich/Germany, 03 November 2006 - Professor Alois Fuerstner from the Max-Planck-Institute for Coal Research in Muelheim/Ruhr received this yearÂ’s Heinrich Wieland Prize for exceptional achievements in the synthesis of glycolipids.
His work was awarded with the Heinrich Wieland Prize for its contribution to make synthetic approaches to this class of molecule possible.
These findings are noteworthy, since they open up the field of biological evaluation of glycolipids for potential therapeutic effects.
LIPID RAFTS IN GLYCOLIPID STORAGE DISEASES (770 words)
The consequences of glycolipid storage on the proteome of lysosomes and late endosomes.
Glycolipid storage diseases have varying degrees of central nervous system involvement and in Tay-Sachs and Sandhoff diseases the neuropathology is very severe and frequently lethal in early infancy.
However, since in the glycolipid storage diseases specific glycolipids accumulate in the lysosome it is speculated that these may form a raft which sequesters raft-associated proteins and they are degraded instead of performing their normal function.
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