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Encyclopedia > Gigantocellular nucleus
Brain: Gigantocellular nucleus
Latin nucleus reticularis gigantocellularis
NeuroNames hier-727
Dorlands/Elsevier n_11/12581282

The gigantocellular nucleus, as the name indicates, is mainly composed of the so called giant neuronal cells. Latin is an ancient Indo-European language originally spoken in Latium, the region immediately surrounding Rome. ... NeuroNames is a system of nomenclature for the brain and related structures. ... Elseviers logo. ...

This nucleus has been known to innervate the caudal hypoglossal nucleus, and responds to glutamateric stimuli. The hypoglossal nucleus extends the length of the medulla, and being a motor nucleus, is close to the midline. ...

The gigantocellular nucleus excites the hypoglossal nucleus, and can play a role in the actions of the said nerve [1].

This nucleus receives connections from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus. Periaqueductal Gray (PAG; also called the central gray) is the midbrain grey matter that is located around the cerebral aqueduct within the midbrain. ...

Retrograde studies have shown that the deep mesencephalic reticular formation and oral pontine reticular nucleus project to the nucleus gigantocellularis.

The dorsal rostral section of the nucleus reticularis gigantocellularis is also involved mediating in expiration (or out-breathing) along with the parvocellular nucleus. Exhalation is the movement of air out of the bronchial tubes, through the airways, to the external environment during breathing. ...


  1. ^ Yang, CC et al. Excitatory innervation of caudal hypoglossal nucleus from nucleus reticularis gigantocellularis in the rat. Neuroscience. 1995 Mar;65(2):365-74.



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