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Encyclopedia > George H. Hitchings

George H. Hitchings (April 18, 1905February 27, 1998) shared the 1988 Nobel Prize in Physiology or Medicine with Sir James Black and Gertrude Elion "for their discoveries of important principles for drug treatment," Hitchings specifically for his work on chemotherapy. April 18 is the 108th day of the year in the Gregorian calendar (109th in leap years). ... 1905 (MCMV) was a common year starting on Sunday (see link for calendar). ... February 27 is the 58th day of the year in the Gregorian Calendar. ... 1998 (MCMXCVIII) was a common year starting on Thursday of the Gregorian calendar, and was designated the International Year of the Ocean. ... 1988 (MCMLXXXVIII) was a leap year starting on Friday of the Gregorian calendar. ... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ... Sir James Whyte Black, OM (born 14 July 1924) received the Nobel Prize for Medicine in 1988. ... Gertrude B. Elion (January 23, 1918 - February 21, 1999) was an American biochemist and pharmacologist, and a 1988 recipient of the Nobel Prize in Physiology or Medicine. ... Chemotherapy is the use of chemical substances to treat disease. ...

Hitchings was born in Hoquiam, Washington, in 1905, and grew up there, in Berkeley, California, San Diego, Bellingham, Washington, and Seattle. He graduated from Seattle's Franklin High School, where he was salutatorian, in 1923, and from there went to the University of Washington, from which he graduated with a degree in chemistry cum laude in 1927, after having been elected to Phi Beta Kappa as a junior the year before. That summer, he worked at the university's Puget Sound Biological Station at Friday Harbor on San Juan Island [1], and received a master's degree the next year for his thesis based on that work. Hoquiam (pronounced ) is a city located in Grays Harbor County, Washington. ... Berkeley as seen from the Claremont Canyon Regional Preserve. ... San Diego County in the Southwest corner of California. ... Nickname: Motto: Official website: www. ... City nickname Emerald City City bird Great Blue Heron City flower Dahlia City mottos The City of Flowers The City of Goodwill City song Seattle, the Peerless City Mayor Greg Nickels County King County Area   - Total   - Land   - Water   - % water 369. ... Seattle Public Schools is the school district for the city of Seattle, Washington. ... In the United States and Canada, the title of salutatorian is given to the second highest graduate of the entire graduating class of an educational institution. ... 1923 (MCMXXIII) was a common year starting on Monday (link will take you to calendar). ... The University of Washington, founded in 1861, is a major public research university in Seattle, Washington. ... Chemistry (derived from the Arabic word kimia, alchemy, where al is Arabic for the) is the science that deals with the properties of organic and inorganic substances and their interactions with other organic and inorganic substances. ... 1927 (MCMXXVII) was a common year starting on Saturday (link will take you to calendar). ... The Phi Beta Kappa Society is an honor society which considers its mission to be fostering and recognizing excellence in undergraduate liberal arts and sciences. ... Puget Sound Puget Sound is an arm (sound) of the Pacific Ocean in the Pacific Northwest of the United States. ... Cars at the entrance to the ferry dock at Friday Harbor. ... A forest on San Juan Island San Juan Island is the second-largest and most populous of the San Juan Islands in northwestern Washington, USA. Washington State Ferries serves Friday Harbor, which is San Juan Islands major population center, the San Juan County seat, and the only incorporated town...

From the University of Washington, Hitchings went to Harvard University as a teaching fellow, ending up at Harvard Medical School. Before getting his Ph.D. in 1933, he joined Alpha Chi Sigma in 1929. During the next ten years, he would work at Harvard and Western Reserve University. In 1942, he went to work for Wellcome Research Laboratories, where he began working with Gertrude Elion in 1944. Drugs Hitchings' team worked on included 2,6-diaminopurine (a compound to treat leukemia) and p-chlorophenoxy-2,4-diaminopyrimidine (a folic acid antagonist). According to his Nobel Prize autobiography, Harvard University is a private university in Cambridge, Massachusetts, USA and a member of the Ivy League. ... Doctor of Philosophy, or Ph. ... 1933 (MCMXXXIII) was a common year starting on Sunday (link will take you to calendar). ... Founded December 11, 1902 at University of Wisconsin, Madison International Headquarters Indianapolis, IN Official Colors Prussian blue & Chrome Yellow Coat of Arms Collegiate Chapters 47 active, 6 pending Alpha Chi Sigma Website Alpha Chi Sigma (ΑΧΣ) is a professional college fraternity specializing in the field of chemistry. ... 1929 (MCMXXIX) was a common year starting on Tuesday (link will take you to calendar). ... Case Western Reserve University is a private research university located in Cleveland, Ohio, USA. It was formed in 1967 by the federation of Case Institute of Technology (founded in 1880 by philanthropist Leonard Case Jr. ... This article is about the year. ... GlaxoSmithKline plc (LSE: GSK NYSE: GSK) is a British based pharmaceutical, biologicals, and healthcare company. ... Gertrude B. Elion (January 23, 1918 - February 21, 1999) was an American biochemist and pharmacologist, and a 1988 recipient of the Nobel Prize in Physiology or Medicine. ... 1944 (MCMXLIV) was a leap year starting on Saturday (link will take you to calendar). ... Leukemia (leukaemia in Commonwealth English) is a cancer of the blood or bone marrow characterized by an abnormal proliferation of blood cells, usually white blood cells (leukocytes). ... Folic acid and folate (the anion form) are forms of a water-soluble B vitamin. ...

The line of inquiry we had begun in the 1940s [also] yielded new drug therapies for malaria (pyrimethamine), leukemia (6-mercaptopurine and thioguanine), gout (allopurinol), organ transplantation (azathioprine) and bacterial infections (co-trimoxazole (trimethoprimA)). The new knowledge contributed by our studies pointed the way for investigations that led to major antiviral drugs for herpes infections (acyclovir) and AIDS (zidovudine).

In 1967 Hitchings became Vice President in Charge of Research of Burroughs-Wellcome. He became Scientist Emeritus in 1976. He died in 1998 in Chapel Hill, North Carolina. // Events and trends World War II was a truly global conflict with many facets: immense human suffering, fierce indoctrination, and the use of new, extremely devastating weapons such as the atomic bomb. ... Red blood cell infected with Malaria, derived from male aria (Italian for bad air) and formerly called ague or marsh fever in English, is an infectious disease which causes about 350-500 million infections with humans and approximately 1. ... Pyrimethamine (Daraprim®) is a medication used for protozoal infections. ... Mercaptopurine (also called 6-MP or by its brand name Purinethol®) is an immunosuppressive drug used to treat leukemia. ... Allopurinol is a white, powdery drug used to treat gout. ... An organ transplant is the transplantation of an organ (or part of one) from one body to another, for the purpose of replacing the recipients damaged or failing organ with a working one from the donor. ... Azathioprine is a chemotherapy drug, now rarely used for chemotherapy but more for immunosuppression in organ transplantation and autoimmune disease such as rheumatoid arthritis or inflammatory bowel disease or Crohns disease. ... Phyla/Divisions Actinobacteria Aquificae Bacteroidetes/Chlorobi Chlamydiae/Verrucomicrobia Chloroflexi Chrysiogenetes Cyanobacteria Deferribacteres Deinococcus-Thermus Dictyoglomi Fibrobacteres/Acidobacteria Firmicutes Fusobacteria Gemmatimonadetes Nitrospirae Omnibacteria Planctomycetes Proteobacteria Spirochaetes Thermodesulfobacteria Thermomicrobia Thermotogae Bacteria (singular, bacterium) are a major group of living organisms. ... Infected (Radio Show) is also the name of an internet radio podcast hosted by Martin Sargent. ... Co-trimoxazole (abbreviated SXT) is a bacteriostatic antibiotic combination of trimethoprim and sulfamethoxazole, in the ratio of 1 to 5, used in the treatment of a variety of bacterial infections. ... Antiviral drugs are a class of medication used specifically for treating viral infections. ... Genera Subfamily Alphaherpesvirinae    Simplexvirus    Varicellovirus    Mardivirus    Iltovirus Subfamily Betaherpesvirinae    Cytomegalovirus    Muromegalovirus    Roseolovirus Subfamily Gammaherpesvirinae    Lymphocryptovirus    Rhadinovirus Unassigned    Ictalurivirus The Herpesviridae are a family of DNA viruses that cause diseases in humans and animals. ... Aciclovir (INN) or aciclovir (USAN), marketed as Zovirax®, is one of the main antiviral drugs. ... Acquired immunodeficiency syndrome, or acquired immune deficiency syndrome (or acronym AIDS or Aids), is a collection of symptoms and infections resulting from the specific damage to the immune system caused by infection with the human immunodeficiency virus (HIV). ... Zidovudine (INN) or azidothymidine (AZT) is an antiretroviral drug, the first one approved for treatment of HIV. It is also sold under the names Retrovir® and Retrovis®, and as an ingredient in Combivir® and Trizivir®. It is an analog of thymidine. ... 1967 (MCMLXVII) was a common year starting on Sunday of the Gregorian calendar. ... 1976 (MCMLXXVI) was a leap year starting on Thursday (the link is to a full 1976 calendar). ... 1998 (MCMXCVIII) was a common year starting on Thursday of the Gregorian calendar, and was designated the International Year of the Ocean. ... City nickname: The Southern Part of Heaven County Orange County Mayor Kevin C. Foy Term Expires: 12/2007 Town Council Laurin Easthom Term Expires: 12/2009 Sally Greene Term Expires: 12/2007 Ed Harrison Term Expires: 12/2009 Cam Hill Term Expires: 12/2007 Mark Kleinschmidt Term Expires: 12/2009...



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