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Encyclopedia > Gamete intrafallopian transfer

Gamete intrafallopian transfer (GIFT) is an infertility treatment in which eggs are removed from a woman's ovaries, and placed in one of the fallopian tubes, along with the man's sperm. This allows fertilization to take place inside the woman's body.


It takes, on average, four to six weeks to complete a cycle of GIFT. First, the woman must take a fertility drug to stimulate egg production in the ovaries. The doctor will monitor the growth of the ovarian follicles, and once they are mature, the woman will be injected with Human chorionic gonadotropin (hCG). The eggs will be harvested approximately 36 hours later, mixed with the man's sperm, and placed back into the woman's Fallopian tubes using a laparoscope.


A woman must have at least one normal fallopian tube in order for GIFT to be suitable. It is used in instances where the fertility problem relates to sperm dysfunction, and where the couple has idiopathic (unknown cause) infertility. Some patients may prefer the procedure to IVF for ethical reasons, since the fertilization takes place inside the body.


As with most fertility procedures, success depends on the couple's age and the woman's egg quality. It is estimated that approximately 25-30% of GIFT cycles result in pregnancy [1] (http://www.child.org.uk/html/malta.php/factsheets/79/), with a third of those being multiple pregnancies.


Many specialists in infertility would look at GIFT as a procedure that is outdated (2004) as pregnancy rates in IVF tend to be equal or better and do not require laparoscopy.


  Results from FactBites:
 
MEFS Journal: Volume 1, No 3, 1996 Abstracts (1599 words)
However, in prospective studies the results of gamete intrafallopian transfer in general were not superior to in vitro fertilization.
The discrepancy in the results of gamete intrafallopian transfer as compared to in vitro fertilization could be explained by the wide range of heterogeneous groups of patients treated by gamete intrafallopian transfer and in vitro fertilization and the higher number of gametes transferred in gamete intrafallopian transfer.
The superior results of gamete intrafallopian transfer as compared to intrauterine insemination in some reports is partially due to the difference in the stimulation protocols between the two groups.
Infertility - Wikipedia, the free encyclopedia (2049 words)
Zygote intrafallopian transfer (ZIFT) in which eggs are removed from the woman, fertilized and then placed in the woman's fallopian tubes rather than the uterus.
Gamete intrafallopian transfer (GIFT) in which eggs are removed from the woman, and placed in one of the fallopian tubes, along with the man's sperm.
Pro-life opposition to the destruction of embryos not transferred in vivo.
  More results at FactBites »

 
 

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