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Encyclopedia > G cell

In medicine, the G cell is a type of cell in the stomach that secrets gastrin.[1] It works in conjunction with gastric chief cells and parietal cells. Download high resolution version (987x1194, 199 KB)Diagram summarising control of stomach acid secretion. ... Download high resolution version (987x1194, 199 KB)Diagram summarising control of stomach acid secretion. ... Medicine is a branch of health science and the sector of public life concerned with maintaining or restoring human health through the study, diagnosis, treatment and possible prevention of disease and injury. ... In humans, gastrin is a hormone that stimulates secretion of gastric acid by the stomach. ... A gastric chief cell (or peptic cell, or gastric zymogenic cell) is a cell in the stomach that releases pepsinogen and rennin. ... Parietal cells (also called oxyntic cells) are cells located in the stomach epithelium. ...

G cells are found deep with the gastric glands of the stomach antrum, and occasionally in the pancreas.[2] The fundus glands (or fundic glands, or gastric glands) are found in the body and fundus of the stomach. ... In anatomy, the stomach (in ancient Greek στόμαχος) is an organ of the gastrointestinal tract involved in the second phase of digestion, following mastication. ... In Biology, Antrum is a general term for a cavity or chamber which may have specific meaning in reference to certain organs or sites in the body. ... The pancreas is an organ in the digestive and endocrine system that serves two major functions: exocrine (producing pancreatic juice containing digestive enzymes) and endocrine (producing several important hormones, including insulin). ...

The vagus nerve innervates the G cells. The vagus nerve (also called pneumogastric nerve or cranial nerve X) is the tenth of twelve paired cranial nerves, and is the only nerve that starts in the brainstem (within the medulla oblongata) and extends, through the jugular foramen, down below the head, to the abdomen. ...

Gastrin-releasing peptide is released by the post-ganglionic fibers of the vagus nerve onto G cells during parasympathetic stimulation. Gastrin releasing peptide (GRP) is released by the post-ganglionic fibres of the vagus nerve which innervate the G cells of the stomach and stimulate them to release gastrin. ... Anatomy and Physiology of the A.N.S. In contrast to the voluntary nervous system, the involuntary or autonomic nervous system is responsible for homeostasis, maintaining a relatively constant internal environment by controlling such involuntary functions as digestion, respiration, and metabolism, and by modulating blood pressure. ...

Gastrin-releasing peptide, as well as the presence of amino acids in the stomach, stimulate the release of gastrin from the G cells. Gastrin stimulates enterochromaffin cells to release histamine. In chemistry, an amino acid is any molecule that contains both amino and carboxylic acid functional groups. ... Enterochromaffin (EC) cells (or Kulchitsky cells) occur in the epithelia lining the lumen of the gastrointestinal tract (GIT; e. ... This article or section does not cite its references or sources. ...

Gastrin also targets parietal cells.

The increase and histamine and the direct stimulation by gastrin, cause parietal cells to increase HCl secretion in the stomach. The chemical compound hydrochloric acid is the aqueous (water-based) solution of hydrogen chloride (HCl). ...


  1. ^ Diagram at gerd.com
  2. ^ Medcyclopaedia at GE iv_1/g/G_cell

GE redirects here. ...

External links

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