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Encyclopedia > Framingham Heart Study

The Framingham Heart Study is a cardiovascular study based in Framingham, Massachusetts. The study began in 1948, and is on its third generation of participants at present. Most of the now common knowledge concerning heart disease, such as the effects of diet, exercise, and common medications such as aspirin, are based on this longitudinal study. It is based at Framingham State College, but involves health professionals from the hospitals and universities of nearby Boston, Massachusetts as well. The circulatory system or cardiovascular system is the organ system which circulates blood around the body of most animals. ... Framingham is the fourth most populous town located in Middlesex County, Massachusetts, USA. As of the 2000 census, the town had a total population of 66,910, making it the most populous town in Massachusetts, and at present, the largest town in North America. ... 1948 is a leap year starting on Thursday (link will take you to calendar). ... Diet can refer to several things: The nutritional diet of an organism or group. ... The word exercise can mean the following: A setting in action or practicing. ... A very old bottle of Aspirin Aspirin or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Longitudinal studies form a class of research methods that involve observations of the same items over a longer time. ... Framingham State College is a public college offering liberal arts and science programs. ... Nickname: Beantown, The Hub (of the Universe), Athens of America Location in Massachusetts Founded  -Incorporated  September 17, 1630  1820, as a city County  Suffolk County Mayor  Thomas Menino (Dem) Area  - Total  - Water  232. ...

One of the crucial questions in evidence-based medicine is how closely the people in a study resemble the patient you are dealing with. Recently the Framingham studies have become regarded as overestimating risk, particularly in the lower risk groups, for UK populations. Nevertheless, they are very useful. Evidence-based medicine is a medical movement based upon the application of the scientific method to medical practice, including long-established existing medical traditions not yet subjected to adequate scientific scrutiny. ...

Many studies and articles criticise the Framingham study. As evidence, the following quote is used: "In Framingham, Massachusetts, the more saturated fat one ate, the more cholesterol one ate, the more calories one ate, the lower people's serum cholesterol...we found that the people who ate the most cholesterol, ate the most saturated fat, ate the most calories weighed the least and were the most physically active." Dr William Castelli 1992 (Director of the Framingham study)

External links

  • Framingham Heart Study- official website
  • BMJ 2003;327:1238-1239 (29 November) - BMJ editorial; "Risk factor scoring for coronary heart disease. Prediction algorithms need regular updating"

  Results from FactBites:
The Framingham Heart Study: Background Information (1230 words)
For 50 years, the Framingham Heart Study and the residents of Framingham, Massachusetts, have been synonymous with the remarkable advances made in the prevention of heart disease in the United States and throughout the world.
Before Framingham, most physicians believed that atherosclerosis was an inevitable part of the aging process and were taught that blood pressure was supposed to increase with age enabling the heart to pump blood through an elderly person's narrowed arteries.
In 1971, the study recruited 5,124 children (and their spouses) of the original cohort for a second study, the "Offspring Study." With two generations worth of data, the Framingham Heart Study acquired an unmatched base of scientific riches.
Framingham Heart Study (225 words)
Directed by the National Heart Institute (now known as the National Heart, Lung, and Blood Institute), it followed 5,209 adults (ages 30–62) from Framingham, Massachusetts, who had not yet developed overt symptoms of cardiovascular disease and who had not suffered a heart attack or stroke.
The study's goal is to learn the circumstances in which cardiovascular diseases arise, evolve and end fatally in the general population.
In 1971 the study enrolled a second-generation group to participate in similar examinations.
  More results at FactBites »



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