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Encyclopedia > Fluoroquinolones

Quinolones and fluoroquinolones form a group of broad-spectrum antibiotics.


Fluoroquinolone antibiotics are highly potent and considered relatively safe. However, they can have potentially troublesome side effects. For example, case reports have implicated their use in rare instances of tendon damage, especially when administered with a systemic corticosteroid.


Mechanism

Quinolones act by inhibiting the bacterial DNA gyrase enzyme.


Examples

External links


  Results from FactBites:
 
Fluoroquinolones: Encyclopedia of Medicine (1085 words)
Fluoroquinolones are medicines that kill bacteria or prevent their growth.
Fluoroquinolones are antibiotics, medicines used to treat infections caused by microorganisms.
Fluoroquinolones are available only with a physician's prescription and are sold in tablet and injectable forms.
Pharmacy Times: Fluoroquinolones: Focus on Safety (1205 words)
Fluoroquinolones are bactericidal agents that exhibit concentration-dependent killing against a broad spectrum of pathogens.
Although seizures are infrequent, fluoroquinolones should be avoided in patients with a history of convulsion, cerebral trauma, or anoxia.
A recent study found that the use of fluoroquinolones was associated with tendon or join disorders in <1% of children—similar to the incidence with the comparator azithromycin.
  More results at FactBites »

 
 

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