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Encyclopedia > Enrofloxacin

Enrofloxacin is a fluoroquinolone antibiotic sold by the Bayer Corporation under the trade name Baytril. Enrofloxacin is currently FDA-approved for treatment of individual pets and domestic animals in the United States. In September of 2005, the FDA withdrew approval of Baytril for use in water to treat flocks of poultry, as this practice was noted to promote the evolution of fluoroquinolone-resistant strains of the bacterium Campylobacter, a human pathogen.[1] Fluoroquinolones such as ciprofloxacin are widely used in the treatment of human disease. Quinolones and fluoroquinolones form a group of broad-spectrum antibiotics. ... Bayer AG (IPA pronunciation //) (ISIN: DE0005151005, NYSE: BAY, TYO: 4863 ) is a German chemical and pharmaceutical company founded in 1863. ... FDA logo The Food and Drug Administration (FDA) is an agency of the United States Department of Health and Human Services and is responsible for regulating food, dietary supplements, drugs, biological medical products, blood products, medical devices, radiation-emitting devices, veterinary products, and cosmetics in the United States. ... Species C. fetus C. jejuni Campylobacter is a genus of Gram-negative bacteria. ... Ciprofloxacin is the generic international name for the synthetic antibiotic manufactured and sold by Bayer Pharmaceutical under the brand names Cipro and Ciproxin (and other brand names in other markets, e. ...


References

  1. ^ http://www.fda.gov/cvm/FQWithdrawal.html FDA statement on withdrawal of Baytril for use in poultry

  Results from FactBites:
 
Enrofloxacin (Baytril┬«) - PetPlace.com (560 words)
Enrofloxacin is thought to inhibit the synthesis of DNA within the bacteria, resulting in bacterial death.
Enrofloxacin is used to treat a variety of infections, including skin infections, urinary tract infections, respiratory infections and wound infections caused by susceptible bacteria.
Enrofloxacin is not effective for treating infections caused by viruses, parasites or molds.
822. Enrofloxacin (WHO Food Additives Series 34) (8289 words)
Enrofloxacin is most effective against gram- negative bacteria and is indicated for infections of the respiratory, gastrointestinal and urinary tracts in cattle, pigs and poultry.
Enrofloxacin was rapidly absorbed and distributed to all tissues, with the highest concentration in the liver and kidney.
Enrofloxacin was not carcinogenic in mice orally dosed at levels equal to 323, 1100, or 3520 mg/kg bw/day in a 2-year long-term toxicity/carcinogenicity study.
  More results at FactBites »

 
 

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