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Encyclopedia > DsDNA

dsDNA is an abbreviation for double-stranded DNA Space-filling model of a section of DNA molecule Deoxyribose nucleic acid (DNA) is a nucleic acid that contains the genetic instructions specifying the biological development of all cellular forms of life (and many viruses). ...


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Investigation of dsDNA Stretching Meso-mechanics using Finite Element Metho... (265 words)
Moreover, the meso-mechanics of dsDNA molecules is then studied based on the proposed model, including the base-stacking interaction between DNA adjacent nucleotide base pairs, the Hydrogen bond of complementary base-pairs and electrostatic interactions along DNA backbones.
In this research, the finite element method based on the continuum mechanics is applied to describe the deformation of dsDNA backbone, and the novel equivalent theory is introduced to simulate the quantum mechanical characteristics of the Hydrogen bond force and stacking interaction between base pairs.
Furthermore, the numerical dsDNA stretching model would be used to study the DNA conformational change driven by the binding of proteins/enzyme to double helix, such as Rec A or Rec BCD protein.
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